Submitted by Red on Sun, 2011-01-09 13:04

 Studies suggest that Vitamin D and the it's downstream Antimicrobial Peptides (AMPS) products may have beneficial effects in Inflammatory Bowel Disease (IBD):

Don't miss this excellent summary table in the above article:
Table 1Table 1-Antimicrobials in the gastrointestinal tract.

 And while epidemiological studies do not necessarily point to a root cause, the studies below are interesting in that they seem to find that Inflammatory Bowel Disease occurs at higher rates in northern latitudes and also increases with affluence (whereby you might assume with greater affluence, people may spend more time indoors, etc):

 Lastly, below is an article on a recent study that discusses just how complicated the whole disease process for Inflammatory Bowel Disease may really be, namely that it may take genetic susceptibility (and potentially low Vitamin D levels) and then potentially even something like a virus (in this case Norovirus) that can alter the gut microbe balance before disease occurs:

Here's a link to the actual study referenced above:

Additional articles on Vitamin D in Inflammatory Bowel Disease can be found on the Vitamin D Council page on Vitamin D and Inflammatory Bowel Disease: