29 Nov 2019

1 Year on Protocol - what next?


Hi there,

Firstly, thank you so much for all the helpful information on this website, which has guided my path of treatment.

I have Chronic Fatigue Syndrome along with the Cpn. (No MS).


I started the combined antibiotic protocol about a year ago (Doxycyline, Azithromycin and gradually introduced the Metronidazole pulses).  Progress has been very slow, but I felt a more significant improvement a couple of months ago - I am now no longer getting sick from viral infections all the time and my battery seems to have a bit more charge in it/I have more vitality about me.  For the first time I felt it was possible the Cpn may have gone.

Recent blood test results show it is still there.   My question is now - should I stay on full time antibiotics a while longer or drop to the intermittent treatment?  The decision will be taken with my integrative medicine Dr, but he hasn't treated anyone on this protocol before.  Whilst on the intermittent treatment, will the bacteria still be killed off?

I'd be grateful for anyone's advice/experience at this stage.

Thanks and regards,


Sara, if you are still carrying C pn, you ought to still be on full time treatment, because even if you have just one cryptic body left which becomes active, you will restart the whole lifecycle again.

Completed Stratton/Wheldon regime for aggressive secondary progressive MS in June 2007, after four years, three of which intermittent.   Still improving bit by bit and no relapses since finishing treatment.


ELISA tests for chlamydial IgA and IgG can remain positive long after the bacteria have been eradicated. In fact you can get a rise in IgA during treatment as dead bacterial fragments stimulate the host production of antibodies.

D W - [Myalgia and hypertension (typically 155/95.) Began (2003) taking doxycycline and macrolide and later adding metronidazole. No medication now. Morning BP typically 110/75]

I am voting for continuing full time abx. I stayed on them for several years and, though my biggest recovery was during the first year, I did not feel confident the disease was eliminated at that point. Since treatment was relatively uneventful, it was easy to simply continue with the meds. (At the beginning, I'd said I would be happy to stay on the abx forever, if it meant getting my life back.)

It makes no sense to try to minimize one's use of antibiotics while fighting the infection that could - literally - end one.

The difference between what we do and what we are capable of doing would suffice to solve most of the world’s problems. Mohandas Gandhi