Cpn endotoxin is about 100 times less powerful than Neisserial endotoxin, but there must be a lot of it released, particularly with the active killing by metronidazole. Hence the need for caution at this stage of treatment. The long-term damaging effect of far more potent endotoxins on the CNS is vividly illustrated by this story: http://www.endotoxin.gmxhome.de/ which resulted in a letter in the BMJ: http://oem.bmjjournals.com/cgi/content/full/60/5/378
One quite common side effect of Cpn treatment is vestibular disturbance. A number of other medics who treat CFS with antibiotics have noticed this. It can go on for months, tends to have a diurnal rhythm and can be quite incapacitating. Its severity seems to be linked to bacterial load. The diurnal pattern suggests that it may be of host origin, perhaps cytokine. Here's a link to a webpage which notes the association between vestibular disturbance and cognitive deficits. http://www.backgroundfacts.com/menieres/COGDIS.htm
9 May 2008 08:38 am
Welcome Ashanty, Recently
Welcome Ashanty,Recently there has been some other discussion about treating children. If you click on the search box & type in children treatment and press Search they should come up. Perhaps you could set yourself up on a blog & then add a signature where you may describe your illness & treatments you are taking. This helps people to answer any questions you may have.Blessings for your journeyCFIDS/ME 26yrs, FMS, IBS, EBV, CMV, Cpn, chronic insomnia, Lymes, HME, Natural HRT peri-M, NAC 2.5 gm, 6-07 Doxy 200 mg day pm, Azith 375 mg M/W/Fday, Pulse#9 750mg 5.5 day, 4-25-8
CFIDS/ME, FMS, MCS, IBS, EBV, CMV, Cpn, H1, chronic insomnia, Chronic Lyme, HME, Babesia, Natural HRT-menopause, NAC 2.4 gm,Full CAP 6-2-07, all supplements+Iodorol, Inositol-depression, ultra Chitosan, L lysine Pulse#27 04-19-10 1gm Flagyl/day-5 days<
Sorry, my English is
Sorry, my English is psobably not too good ...I m going trough these pages and agree with most of the things written here. I also experienced the diurnal rhythm and to my impression it is linked to the cortisol level of the blood. I got high fever in the morning (around 10 o clock) and at night at 2-3 am.My child which I breastfed up to this breakdown is also infected and has difficulties in speaking and motor skills. Is there anyone who has experience in treating children (6 years)???