29 Dec 2019
Author
Spidey
Title

Tinidazole questions

Body

1. Is tini as effective as flagyl?

2. Why are there generally fewer side effects of tini? My assumption is that is isn't killing bacteria as well as flagyl.

Comments

boadicea

30 Dec 2019 05:59 am

I found tinidazole far tougher to tolerate than metronidazole, so it’s not necessarily the case that everyone finds it easier. And I don’t think ‘side effects’ of a drug necessarily correlates with its effectiveness at killing bacteria. 
 

Neuro symptoms & many health problems from 1989. NAC+all supps(04/11) CAP(05/11-10/17)

Sarah

30 Dec 2019 06:47 am

Quite: both are equally effective but most people find metronidazole tougher but not everyone. Until I read that tinidazole was usually preferred, I thought I wouldn't notice a difference, but when I took some, I did and straight away.

Sarah

Completed Stratton/Wheldon regime for aggressive secondary progressive MS in June 2007, after four years, three of which intermittent.   Still improving bit by bit and no relapses since finishing treatment.

Kiki

30 Dec 2019 07:18 am

Hi Sarah and Boadicea

In what way did you find Tini harder on you Boadicea and how did you find Metro better for you? Also Sarah do you think it's worth me changing tactics with Metro rather than the Tini I have taken so far? Bearing in mind I now also seem to have a life time of supply in the house due to unforseen shipping haha!

Kiki

boadicea

30 Dec 2019 01:49 pm

It sounds to me as though you are doing fine with tolerating tinidazole, Kiki, so, personally, I would stick with that if I were you.  As you feel you have been getting worse, though, I just think you need to go slower with pulses and see how you get on - perhaps try 3 days pulses for while.  One of the things I learnt along the way is that 'more' isn't necessarily 'better'. We have to learn to be tortoise, not hare.

I've always struggled with all the abx - herx effect of flu-like symptoms and sickness and also secondary porphyria. When I started pulses, a tablet of tinidazole was unbearably debilitating, to the point of being unable to get out of bed and look after myself and the effects lasted too long, but I then found a tablet of metronidazole was slightly more tolerable.  I did eventually move to tinidazole again, after a few years, and was OK with that - but still never more than 2 or 3 day pulses or the die-off was intolerable again. I think that's just the way it was for me.

Neuro symptoms & many health problems from 1989. NAC+all supps(04/11) CAP(05/11-10/17)

Sarah

30 Dec 2019 01:42 pm

Kiki and Spidey, there seems to be a common misapprehension about the nitraimidizoles that if they don't hurt, they won't work. Since I started with metronidazole and only changed to tinidazole later on in the treatment, I can't say that this is the case, but many people have taken nothing but tinidazole and got better.

You could both of you, take one and then try the other, but beware of the tears with metronidazole!

Sarah

Completed Stratton/Wheldon regime for aggressive secondary progressive MS in June 2007, after four years, three of which intermittent.   Still improving bit by bit and no relapses since finishing treatment.

ElizabethAnne

31 Dec 2019 04:23 am

Hi everyone,

Happy New Year to you all! Start of the extra decade, eh? Let’s all pray for a good year.  I’ve just about reached the end of the 12 month cycle, soon to move to the intermittent phase. 
I’ve had no attacks or new episodes since I started the Doxycycline, and I feel I am slowly getting better.
Also, something I noticed in its absence.  When the weather is cooler, even if I’m wrapped up and comfortable, my first finger, pointing finger, on my left hand would go completely white and bloodless. It would be totally numb. The only way I could make it better was to suck on it, hard, like a child. And the blood would move into the finger again.

This would happen even if it wasn’t really that cold, so even though this winter has not been very cold yet, I would’ve had it.

Now my hands are pink and warm. Ta da!!
My fingers are pain-free, warm, normal! I don’t need to wear gloves any more. I used to have to all the time because my fingers would ache with pain at the coldness all the time. 
😊

The light I glimpsed at the end of the tunnel turned out to be real. 

Best wishes to you all,

xx Lizzie

Elizabeth Anne

neenavyas

1 Jan 2020 12:23 am

wonderful you dont have to suck your finger like a child. As a child I used to suck so hard that one of my fingers became slightly crooked!

It is so wonderful to hear you are so much better and are thinking of miving to intermittent. But do ask Sarah/ David and may be you should continue with the current plan for at least a few more months.

Best for New Year. Have you moved to Spain, to warmer climes?

Neena

I am 76 years old. My daughter-in-law was diagnosed with MS and we are all very keen for her to start this new antibiotic treatment. We hope to be able to do this in the next couple of weeks by finding a doctor willing to deal with any issues like reactions that may crop up. My daughter-in-law is 43 years old.

I have been an active poilitical journalist most of my life and have felt for a long time that there must be a cure out there for MS which the medical community has largely ignored. I am very excited by the Wheldon protocol.

ElizabethAnne

1 Jan 2020 05:51 am

Hi Neena, we're still here in England. We have to sell our flat first before we move. We hope that now after the election just had, things will start to sell again.

I'll keep you updated.
xx

Lizzie

Elizabeth Anne

boadicea

1 Jan 2020 04:05 am

Lizzie - it sounds as though you have made brilliant progress. Well done you. I think it’s the improvement of small things, especially ones which I hadn’t necessarily had in mind, which always amazed me the most.

You mention possibly moving to intermittent soon. Is that because you are now completely symptom free, with no reaction at all to the pulses, or is it because you always had 12 months in mind?  Unless you are symptom free and have been for a while, I would, personally, stick with it for a bit longer before moving to intermittent. One thing which you could perhaps consider, if you are tolerating the pulses easily, is gradually extending the pulses, to do more than the usual 5 days, before moving to intermittent. I was never able to do that, as I always struggled with the pulses, but I recall some doing that in the past. 
 

Hoping the new decade brings you good things.

Neuro symptoms & many health problems from 1989. NAC+all supps(04/11) CAP(05/11-10/17)

ElizabethAnne

1 Jan 2020 05:59 am

Hi Boadicea, thanks for your comments.

Well, I've had no symptoms at all since I started the protocol a year ago. I also had no adverse reaction to Metronodizole, apart from feeling a bit achy for the first pulse. Since then the pulses have been quite fine. 

What do you think? I was looking at my charts the other day  -- a record of what pills to take when - and realised it had been a full year. I just decided to stop the anti biotics, but will continue with the supplements. I've felt for ages and ages that CPn was dead and gone and I need to heal. Which I am, slowly.

I was planning on a two-week course (including pulse) at the end of Feb. 

Any comments? Thanks again. I really welcome the input.

 

Cheers,
Lizzie xx

 

Elizabeth Anne

boadicea

1 Jan 2020 07:29 am

Hmm, from what you are saying, it does sound like time to go to intermittent and see how you get on.  My experience was very different to yours, but I have a friend who followed a similar path to yours, a very long time ago now, and she did 12 months full time and then went to intermittent for a couple of year and that did seem to serve her well. Personally, I wouldn't stop completely without doing some intermittent - by which I mean two weeks including a pulse.  The bacteria can be a very sneaky one and now that you've come this far, it's seems better to go that bit extra than to stop outright and then regret it. xx

Neuro symptoms & many health problems from 1989. NAC+all supps(04/11) CAP(05/11-10/17)

neenavyas

2 Jan 2020 03:26 am

Better to overdo the abx slightly than deal with the bug showing its strength to destroy once again and then begin all over again. Cheers.

Neena

I am 76 years old. My daughter-in-law was diagnosed with MS and we are all very keen for her to start this new antibiotic treatment. We hope to be able to do this in the next couple of weeks by finding a doctor willing to deal with any issues like reactions that may crop up. My daughter-in-law is 43 years old.

I have been an active poilitical journalist most of my life and have felt for a long time that there must be a cure out there for MS which the medical community has largely ignored. I am very excited by the Wheldon protocol.

Jan Figtree2019

2 Jan 2020 03:56 pm

Congrats on finishing one year of the CAP!  

I'm interested in how you will schedule your intermittent CAP.     I am going to stick with the full protocol for a few more months.   

I can't find the general information about how to transition from full-time protocol to intermittent protocol.  If you have the link/page in the general information could you post it?

 

Happy New Year!

Jan

 

56 y.o. with possible dual diagnoses that I am working to confirm this year: Ankylosing Spondylitis and Scleroderma, and minor Psoriasis.

Jan Figtree2019

4 Jan 2020 07:17 pm

I printed it off and stuck it on my kitchen cabinet.

Lizzie, I am going to count my year starting from the date I started with the Tinidazole (the full Combined Antibiotic Protocol).   Is this in line with your thinking?  

 

Thanks much for the link!

Jan

 

56 y.o. with possible dual diagnoses that I am working to confirm this year: Ankylosing Spondylitis and Scleroderma, and minor Psoriasis.

Astrodiana

17 May 2020 09:52 am

The pamphlet says "this medication may affect your abilty to father a child"!!  of course we wonder what this is about?  Thinking we need to go to Flagyl for him.  Any thoughts on this?

 

Astrodiana

29 Dec 2019
Spidey