A number of articles and studies suggest that Vitamin Di provides benefit in the prevention and treatment of Multiple Sclerosis:
Vitamin D and calcium deficits predispose for multiple chronic diseases
Clinical implications of a possible role of vitamin D in multiple sclerosis
- Vitamin D status is associated with relapse rate in pediatric-onset MS
While most studies that suggest Vit D3 is beneficial in Multiple Sclerosis are epidemiological in nature, a recent open study of 12 patients by Kimball, et al found that the number of lesions per patient (assessed with a nuclear magnetic brain scan) decreased in a high-dose Vitamin D3 treatment group from the initial mean of 1.75 to the end-of-study mean of 0.83:
Studies suggest that Vitamin D may provide benefit in Multiple Sclerosis through several different mechanisms. First Vit D provides antimicrobial benefits, again through several mechanisms:
Vitamin D also downregulates inflammationi and many of the downstream tissue-destroying products that have been shown via studies to play such an important role in Multiple Sclerosis:
And importantly, studies also suggest that Vitamin D plays an important role in nervous system function and repair:
Numerous other studies on the beneficial effects of Vitamin D in Multiple Sclerosis can be found on the Vitamin D Council page on Vitamin D and Multiple Sclerosis: