Submitted by Red on Sat, 2009-06-06 15:03


Studies seem to suggest that Vitamin D3 plays an important role in production of  Defensins, just is it apparently does with the more widely discussed antimicrobial peptides, Cathelicidins (LL-37):

 While less discussed than their antimicrobial "cousins", cathelicidins, studies suggest that Alpha and Beta Defensins also play an important role in host defense.   Here are a few such studies: Alpha Defensins (also knowns as Neutrophil Defensins):

 Beta Defensins:

  Here's an excellent article on the various currently identified defensins and their molecular mechanisms of action:

   Studies suggest that in addition to their antimicrobial effects, defensins may also play an important role in regulating immune responses and inflammation, as well as in wound repair: