Serology

Tissue testing for bacterial signs.

Results, and Clinical Performance of Five PCR Assays for Detecting Chlamydia pneumoniae DNA in Peripheral Blood Mononuclear Cell

Submitted by Jim K on Sun, 2005-09-04 10:45

J. B. Mahony,1,2,* S. Chong,1 B. K. Coombes,1 M. Smieja,1 and A. Petrich1,2
Hamilton Regional Laboratory Medicine Program, St. Joseph's Hospital,1 and Department of Pathology and Molecular Medicine, McMaster University,2 Hamilton, Ontario, Canada
Link here

Received 18 January 2000/Returned for modification 31 March 2000/Accepted 4 May 2000

Chlamydia pneumoniae has been associated with atherosclerosis and coronary artery disease (CAD), and its DNA has been detected in atheromatous lesions of the aorta, carotid, and coronary arteries by a variety of PCR assays. The objective of this study was to compare the performances of five published PCR assays in the detection of C. pneumoniae in peripheral blood mononuclear cells (PBMCs) from patients with coronary artery disease.

Serological evidence of Chlamydia pneumoniae in asthma.

Submitted by Jim K on Wed, 2005-08-24 20:34

Serological evidence of infection with Chlamydia pneumoniae is related to the severity of asthma.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=retrieve&db=pubmed&list_uids=10706488&dopt=Abstract

  • Chlamydia pneumoniae as an Emerging Risk Factor in Cardiovascular Disease
  • Murat V. Kalayoglu, MD, PhD; Peter Libby, MD; Gerald I. Byrne, PhD , JAMA. 2002;288:2724-2731 http://jama.ama-assn.org/cgi/content/abstract/288/21/2724