Interstitial cystitis

Chronic irritation of bladder

Jim’s Story- Chlamydia Pneumoniae and Chronic Fatigue/Fibromyalgia

Submitted by Jim K on Sat, 2005-09-17 20:56

The Tunnel of Illness

I want to update my story on the front end so readers know even before reading the "agony post" how much benefit I've gotten from the treatment. It is August 26th, 2006. Coming up on two years I've been on the Combined Antibiotic Protocol (CAP) for Chlamydia pneumoniae (Cpn). A recent forum poster asked if anyone with CFS has improved on the CAP. My response:

Damned right I'm getting better!When I started the CAP I was in a 2 year slide after 25 years of CFS, then added FMS. For many years I'd struggled and somehow maintained a semblance of a life. Then over 2 years my pain, brain fog, restricted functioning, etc. slid to a point where I had to stop traveling and could for the first time see the possibility that I would become bedridden eventually.

Essential Observations by Dr. Charles Stratton on Chlamydia Pneumoniae Infection and Disease

Submitted by Jim K on Tue, 2006-09-12 16:57

I am very excited to present the following article that summarizes Dr. Stratton's recent observations on Chlamydia pneumoniae infection. Putting it together has contributed greatly to my own understanding of Cpn as well as to my appreciation of Dr. Stratton's generosity with his time, and his great depth of knowledge of this area. Thanks to him for his contribution.

Jim K

Recent observations by Dr

Recent observations by Dr. Charles Stratton on Chlamydia Pneumoniae (Cpn) Infection

Prostatitis, Prostate Cancer and Chlamydia Pneumoniae

Submitted by Jim K on Wed, 2006-09-06 16:31

Stratton et al found evidence of Cpn in interstitial cystitis (IC) in a study which is listed in our research pages. In a recent web excursion I found this researcher's page which describes a number of studies finding quite high rates of Cpn in prostatitis, BHP, and even prostate cancer:

http://home.swipnet.se/isop/mazzoli.htm

The research looks solid to me. Worth taking a look. 

Diseases associated with Cpn: the exhaustive list

Submitted by Jim K on Sun, 2006-01-22 08:41

I have culled from Mitchell & Stratton patent #6,884,784 an exhaustive list of diseases where Cpn has been implicated as a possible cause or co-factor (reference: Mitchell & Stratton patent #6,884,784):

Diseases where an association has been discovered between chronic Chlamydia infection of body fluids and/or tissues with several disease syndromes of previously unknown etiology in humans which respond to unique antichlamydial regimens include:

Editorial comment: Strong findings from their research. If you have any of these it suggests to me that at least an empirical course of the combination antibiotic therapy is strongly indicated, with or without serology.


Multiple Sclerosis (MS)
Rheumatoid Arthritis (RA)
Inflammatory Bowel Disease (IBD)
Interstitial Cystitis (IC)
Fibromyalgia (FM)
Autonomic nervous dysfunction (AND neural-mediated hypotension);
Pyoderma Gangrenosum (PG)
Chronic Fatigue (CF) and Chronic Fatigue Syndrome (CFS).

Stratton/Mitchell & Siram Case Reports

Submitted by Jim K on Sat, 2006-01-21 20:33

Does it work?

It has been noted that most users of the combination antibiotic protocols commenting here have not been on the treatment long enough to give a big enough pool of reports to feel assured of the efficacy of this approach. I had asked Drs. Stratton, Wheldon, and Powell to perhaps tally up at least some basic numbers from their case experience to help us out with this problem, but this would involve problems of confidentiality and use of private data, etc.  

Then, I suddenly realized that we already have a good list of anecdotal reports of response to treatment reported data available to us... right in the Stratton/Mitchell patent materials! (Sheepish, embarrassed grin). So I took it as a project to summarize this data by disease treated. Occasionally I have used the exact wording from the patent materials as they were brief and descriptive. We have the full text referenced in our treatment and links if you want to see more detail.

All reported had with positive serology for Cpn using the highly sensitive tests developed by Stratton/Mitchell. I left out a few whose diagnosis was not clear to me, you can see them in the patent materials #6,884,784
All on some form of the combination antibiotic therapy protocol.

Chlamydia Pneumoniae in Interstitial Cystitus

Submitted by Jim K on Wed, 2005-08-31 20:44

POTENTIAL ROLE OF CHLAMYDIA PNEUMONIAE IN THE PATHOGENESIS OF INTERSTITIAL CYSTITIS. Gregory L. Alberts, Charles W. Stratton, William M. Mitchell, Jenny J. Franke. Vanderbilt University School of Medicine, Nashville, TN

INTRODUCTION: Chlamydia pneumoniae is now recognized as an important human pathogen. As an obligate intracellular parasite, it is difficult to detect by routine cultures, can cause chronic infections, and may not elicit an acute inflammatory response. C. pneumoniae is commonly associated with respiratory tract infection, but has also been implicated in the development of coronary artery plaques and chronic inflammatory conditions such as multiple sclerosis. Our recent data using polymerase chain reaction (PCR) analysis of urine revealed that 71% of patients with interstitial cystitis (IC) were positive for C. pneumoniae. These data suggest a potential role for this organism in the development of IC. We present our data using tissue culture detection of C. pneumoniae in both control patients and patients with interstitial cystitis to further investigate this association.