Rifampicin/Rifampin Question - Need help!

Hit to all group members!

I have 2 questions regarding Rifampin which I started today.

1. can I take ursodiol together with rifampin?

 

2. Can I take moppers together with rifampin (Charcoal or cholestyramine)

 

Thanks a lot

Rifampin must always be taken with no food - on an empty stomach. The literature says this unequivocally. And moppers, by their nature, will negate the action of Rifampin, when taken within 2 hours of it. For the first 16 months, I waited 2 hours after pills or food to take it, then 2 hours after. This was, in retrospect, probably overkill (not a funny joke!).

This time - the final 4 months of abx - I waited the usual 2 hours  before, but waited only a (full) hour after. It worked. For some of the middle abx time (a year of so in the middle) I took Doxy and Azith all together at the same time. The last 4 months, when I was doing all abx at the same time - the final test - I split Rifampin and Doxy into am and pm, taking Doxy 1 hour after Rifampin - with some food, because after 4 years of Doxy on an empty stomach, I got nauseated.

Rica

3/9 Symptoms returning. Began 5 abx protocol 5/9 Rifampin 600, Amox 1000, Doxy 200, MWF Azith 250, flagyl 1000 daily. Began Sept 04 PPMS EDSS 6.7 Now good days EDSS 1 Mind, like parachute, work only when open. Charlie Chan  In for the duration.&am

@katman: For the first 16 months, I waited 2 hours after pills or food to take it, then 2 hours after. This was, in retrospect, probably overkill (not a funny joke!).

Thanks katman! But what was an overkill?  Did you took charcoal or colestyramine?

Cesare

Male 38 years (Germany),CFIDS, IBS, Enterovirus, Cpn and Bartonella, Dientamoeba fragilis positive. Started Cap on 02/19/08, Currently taking Bactrim, Flagyl, soon adding Malarone and Clindamycin for suspected protozooa. 

The instruction leaflet says Rifampin once per day. Since I started today my plan is beginning for the first weeks with 2x150 and then going up to 600 once a day.

Is it ok to take the whole dose once a day?

Male 38 years (Germany),CFIDS, IBS, Enterovirus, Cpn and Bartonella, Dientamoeba fragilis positive. Started Cap on 02/19/08, Currently taking Bactrim, Flagyl, soon adding Malarone and Clindamycin for suspected protozooa. 

Just began rifmapin less than one week ago. I am taking it on an empty stomach, but it's only getting 30 minutes afterward; the instructions don't say how long the stomach has to stay empty, and I have to get to work!

I don't think charcoal is a good idea within 2 hours either way of rifampin; it might absorb too much of the rifampin and keep it from entering the circulation.

Ron

On CAP for CFS starting 01/06 (NE Ohio, USA)

Began rifampin trial 1/14/09

Currently: on intermittent

Have a look at my post here for some more detail on rifampin and food. Giving it only a 30-minute lead really shouldn't be a problem. By the way, since making that post, I think I have noticed a difference between taking it at the same time as food, and giving it a 30-minute lead; it's more potent if you give it the half-hour of head start, and that's what I'm doing now. But even taking it at the same time doesn't entirely destroy its efficacy.

Norman,katman and paron and everyone who takes rifampicin.

Do you take the whole dose once a day? or divided in 2 doses?

Male 38 years (Germany),CFIDS, IBS, Enterovirus, Cpn and Bartonella, Dientamoeba fragilis positive. Started Cap on 02/19/08, Currently taking Bactrim, Flagyl, soon adding Malarone and Clindamycin for suspected protozooa. 

I took it twice a day - wanted to get everything I could from it. Rica

3/9 Symptoms returning. Began 5 abx protocol 5/9 Rifampin 600, Amox 1000, Doxy 200, MWF Azith 250, flagyl 1000 daily. Began Sept 04 PPMS EDSS 6.7 Now good days EDSS 1 Mind, like parachute, work only when open. Charlie Chan  In for the duration.&am

Twice a day, here, too!

Ron

On CAP for CFS starting 01/06 (NE Ohio, USA)

Began rifampin trial 1/14/09

Currently: on intermittent

Cesare, by "overkill" I just meant that I was being harder on myself than I really needed. At the time, I was just beginning, had very little guidance, only the brochure that came with it, and wanted all I could get from it. I got what I was after. Rica

3/9 Symptoms returning. Began 5 abx protocol 5/9 Rifampin 600, Amox 1000, Doxy 200, MWF Azith 250, flagyl 1000 daily. Began Sept 04 PPMS EDSS 6.7 Now good days EDSS 1 Mind, like parachute, work only when open. Charlie Chan  In for the duration.&am

@katman: Oh I thought the overkill had something to do with the time you spaced the moppers from rifampicin...
Male 38 years (Germany),CFIDS, IBS, Enterovirus, Cpn and Bartonella, Dientamoeba fragilis positive. Started Cap on 02/19/08, Currently taking Bactrim, Flagyl, soon adding Malarone and Clindamycin for suspected protozooa.