Supplements currently recommended as of 2/8/06. Those in yellow are considered priority for protection from treatment toxicity.

Everything else is recommended or has been found useful in treatment.

Individual sensitivities to supplements and medications may vary.

Be sure to find a good quality source of supplements and look for the most absorbable formulations.

Check with your doctor before taking these or any other medications or supplements as they may interact with your particular health condition, or with other medications.

Supplements to Protect Cells and Foster Regeneration Specific to Cpn Infection

Name

Dosage

Mode of Action

Comments

References

Folic acid

400 mcg twice per day

Needed for cell rebuilding

 

Vitamin C

At least1 gram twice per day

Antioxidant, anti-endotoxin

 

N-acetyl-Cysteiine (NAC)

600mg 2x per day

Supports and protects liver against toxicity.

Kills Cpn Elementary Bodies. (EB’s)

Two week course essential before starting any antibiotics and continuous throughout protocol.

 

Vitamin D

4000iu is recommend-ed: cholecalciferol

Immune system support.

Less may be needed in infections other than MS and CFS

Blood tests may be useful

Selenium

200 mcg once per day) should be taken with the vitamin E

Antioxidant

 

Acetyl L-Carnitine

500 mg twice per day

Supports mitochondrial energy.

Liver protectant. Cell and muscle energyizer.

Ubiquinone (coenzyme Q10)

30-200 mg twice per day

Supports mitochondrial energy.

 

Alpha-lipoic acid

150-400 mg twice per day

Antioxidant, protective.

 

Magnesium (may be combined with calcium)

300mg 2-3x per day

Both taken remote from antibiotics as interfere with antibiotics absorbtion

Seen to be significantl;y depleted in Chronic Fatigue and Fibromyalgia

Biotin

5 mg twice per day

   

Vitamin E(alpha tocopherol)

400 units twice per day

Antioxidant

 

Quercetin

400 - 500 mg twice per day

Antichlamydial, anti-inflammatory, antioxidant., anti-endotoxin

 

Evening Primrose Oil

1 G daily

Lipids form large portion of nerve cells.

Nerve repair

Omega 3 fish oil

1000mg 1-3x daily

Lipids form large portion of nerve cells.

Nerve repair

Melatonin

1.5-9mg either at dinnertime or just before bed

Antioxidant, antichlamydial, restores hypothalamic pituitary imbalance caused by chronic Cpn

Normalizing sleep.

May increase or interfere with certain antidepressants

Glucosamine

750 - 1000 mg two or three times per day

Aids in connective tissue regeneration.

Particularly when arthritic symptoms are being treated

Chondroitin sulfate

250 - 500 mg twice per day) should also be included

Aids in connective tissue regeneration.

Particularly when arthritic symptoms are being treated in protocol

L-Glutamine

2 - 4 grams twice per day

   

Supplements recommended in Stratton/Mitchell information on Secondary Porphyria caused by Chlamydia pnemoniae infections. http://www.cpnhelp.org/?q=stratton

Testing for porphyrias and pre-treatment with agents below is recommended before beginning a Combination Antibiotic Protocol (CAP) if porphyria is suspected or found, otherwise initiation of CAP can worsen it.

Individual sensitivities to supplements and medications may vary.

Check with your doctor before taking these or any other medications or supplements as they may interact with your particular health condition, or with other medications.

Supplements/Medications to Counter Porphyric Reactions

Name

Suggested Dosage

Mode of Action

Comments

References

B12 injections

3mg w 1mg lidocaine twice a day for first three days, then twice per day 2-3x/week for next three weeks, then 3mg 1x per week during treatment

Hugely depleted by heme byproducts.

Supports detoxification by methylization. Injection discomfort.

Sublingual B12

5000mcg 3x/day

Hugely depleted by heme byproducts.

Supports detoxification by methylization.

Glucose

 

Needed by host cells to counter reduced cellular energy from Cpn

Not for diabetic patients

Vitamin B-1 (thiamin)

100 mg twice per day

Needed to help cells utilize glucose

 

Vitamin B-2 (riboflavin)

100 mg twice per day

Needed to help cells utilize glucose

 

Vitamin B-5 (panto-thenate),

100 mg twice per day

Needed to help cells utilize glucose

 

Vitamin B-6

pyridoxine 100 mg twice per day or pyridoxal-5 phosphate 25 mg twice per day

Needed to help cells utilize glucose

Counters peripheral neuropathy symptoms., neuro-protective.

 

Activated Charcoal

2-4-grams 2 or 3 times per day at least 2 hrs before and 2hrs after meals or meds.

Absorbs porphyrins and endotoxins in gut.

Eases stomach discomfort and gas.

Absorbs a variety of toxic substances.

Can be constipating.

Must be taken away from meals, meds, supplements or absorbs them too.

Supplements currently recommended as of 2/8/06. These have been found pragmatically useful in treatment to counter Cpn endotoxin. Individual sensitivities to supplements and medications may vary. Be sure to find a good quality source of supplements and look for the most absorbable formulations.

Check with your doctor before taking these or any other medications or supplements as they may interact with your particular health condition, or with other medications.

Supplements Supportive to Counter Endotoxic Reactions

Name

Dosage

Mode of Action

Comments

References

Niacin

500- 2000mg (with liver monitoring) spread over day or via time release.

Counters niacin depletion by Cpn. Assists in production of anti-Cpn bioagents. Counters endotoxin reactions.. Helps with chronic headaches.

Counters coldness reaction from endotoxin.

Lowers cholesterol (espec. LDL).

Causes flush reaction. Must work up slowly.

Can be liver toxic if other compromises to liver especially in time release. Should have liver monitoring at high doses.

Garlic,

Horny Goat Weed,

Ginseng, & Ashwa-gandha

2 capsules each, 2 – 3 times per day.

All increase the activity of NOS and may be synergistic in combination with niacin. Increasing nitric oxide usually decreases FM related muscle pain and anxiety.

No cautions unless specific sensitivity.

Charcoal

As described under anti-porphyria supplement

   

Vitamin C Flush

1-2 grams (1-2 tsp) powdered buffered Vit C. every 15 minutes in 8oz H2O until bowel evacuation occurs.

Endotoxin soaks up Vitamin C in large amounts. This is a strategy for more acute effects, e.g. third day of Flagyl pulse.

Since it causes bowel evacuation and clearance, should be used before medications and eating.

Buffered C contains minerals which interfere with antibiotic absorption, so wait two hours

Supplements currently suggested as of 2/8/06. Those in yellow are considered essential for protection from CAP treatment antibiotics.

Individual sensitivities to supplements and medications may vary. Be sure to find a good quality source of supplements and look for the most absorbable formulations.

Check with your doctor before taking these or any other medications or supplements as they may interact with your particular health condition, or with other medications.

Anticandidal and Other Supplements

Name

Dosage

Mode of Action

Comments

References

Acidophilus and other “good” intestinal flora

See recommended dosage by manufacturer.

Replaces intestinal flora killed by antibiotics and/or imbalanced by Cpn, Candida, etc.

Helps prevents C. Difficile infection from antibiotics.

Helps intestinal symptoms.

Best is a multi-flora formulation.

Enteric coated may help better survive stomach acids.

Essential for using CAP’s

 

Olive leaf extract

1-2 caps twice a day

Anti-viral, anti-candidal, antibacterial.

.

Stimulates NK cell production, so is immune boosting

 

Oregano oil

As directed

Antifungal, anticandidal

Can be used as preventative or treatment of intestinal candida.

 

Diflucan

200mg 2-3 times per week

 

Prescription.

Uses p450 liver enzymes for metabolism, so caution if liver is effected.