Not just ATP, but cholesterol too!
Has anyone tried desipramine in combination with antibiotics? Desipramine is a functional inhibitor of acid sphingomyelinase (FIASMA), an enzyme which facilitates cholesterol trafficking. The sinister nature of Cpn extends beyond the parasitism of ATP stores to include LDL cholesterol as well! Professor Jason Carlyon in the Department of Microbiology and Immunology at the Virginia Commonwealth University Medical Center has been researching the inhibition of ASM as an alternate/adjunct therapy to antibiotics for the treatment of infections by intracellular bacteria. He has shown that de