MediTest
3 Jul 2019
Author
jean2
Title

Interesting Background - TWAR- A Human C Psittaci Strain

Body

N Engl J Med. 1986 Jul 17;315(3):161-8.

A new Chlamydia psittaci strain, TWAR, isolated in acute respiratory tract infections.

Comments

N Engl J Med. 1986 Jul 17;315(3):161-8.

A new Chlamydia psittaci strain, TWAR, isolated in acute respiratory tract infections.

Grayston JT, Kuo CC, Wang SP, Altman J.

Abstract

During a 2 1/2-year period, we studied 386 University of Washington students with acute respiratory disease, to determine whether a Chlamydia psittaci strain, here designated TWAR, is an important respiratory pathogen. Serologic evidence of recent TWAR infection was found in 13 students, and the organism was isolated from 8 of these. TWAR infection occurred in 12 percent of the students who had pneumonia (9 of 76), 5 percent of those with bronchitis (3 of 63), and 1 percent of those with pharyngitis (1 of 150). The TWAR infections occurred throughout the study period. Pharyngitis, often accompanied by laryngitis, was a common first symptom. Clinically, the infections resembled those with Myco-plasma pneumoniae; therefore, the patients were given courses of erythromycin used for the treatment of M. pneumoniae infections. This therapy proved to be inadequate. The limited data available suggest that the TWAR strain is a "human" C. psittaci that is spread from human to human, without a bird or animal host.

PMID:
3724806
DOI:
10.1056/NEJM198607173150305

I think I have a severe case of cpn,in the brain which I got about 8 months ago (Oct. 2018).  

I have a lot of issues with depression, balance, eyesight, ear and teeth problems.  Most important, I have brain shrinkage, and some strange symptoms of that. Does anyone share these issues?

Gosh, this is an old paper: it's good that all the old papers can be stored digitally now.

Completed Stratton/Wheldon regime for aggressive secondary progressive MS in June 2007, after four years, three of which intermittent.   Still improving bit by bit and no relapses since finishing treatment.

but I think it gives interesting information about the two different strains and how connected they are. Cpn was once considered a new strain of c psittaci.

I think I have a severe case of cpn,in the brain which I got about 8 months ago (Oct. 2018).  

I have a lot of issues with depression, balance, eyesight, ear and teeth problems.  Most important, I have brain shrinkage, and some strange symptoms of that. Does anyone share these issues?

Yes, but not now: things have moved on. Stratton hadn't started his work n the pathogen then: in fact, he might still have been in the army!

Completed Stratton/Wheldon regime for aggressive secondary progressive MS in June 2007, after four years, three of which intermittent.   Still improving bit by bit and no relapses since finishing treatment.