Herx reactions and Biological rhythm

Hi,

1rst question :

Can you tell me what are Herxeimer reactions normally when treating Cpn ?

If you don't have any Herxeimer reactions, does it mean that treatment is not good and that it must be changed ?

2nd question :

Do you have any cocktail of meds to restablish biological rhythm ? Melatonin or others meds ?

Thanks.