Niacin vs. INH

I was reading recently that INH is a compound of Niacin.  If that is the case, might that explain the reason why INH is useful in that it may have the same sort of activity against CPn as Niacin?  Further, I'm wondering whether Niacin has the same sort of affect as INH.  I know many take mega doeses of Niacin and get a reaction out of it.  I have before, though I didn't keep it up. 

I guess I wonder if I should think about Niacin in the same way I think about NAC.  NAC is a substitute for amoxicillin/penicillin basically, could not Niacin substitute for INH in the same manner?  It certainly would be safer from a liver standpoint...

John,  Niacin in high doses is also a liver threat.

Joyce~caregiver-advocate in Dallas for Steve J (SPMS).  CAP since August 06, antivirals, heavy metals chelation, LDN, Metanx, Lunesta, GF/CF diet, Lauricidin, oral IgG/lactoferrin/IGF-1 booster, gamma oryzanol, astaxanthin.

Joyce~caregiver-advocate in Dallas for Steve J (SPMS).  CAP since August 06, antivirals, heavy metals chelation, LDN, Metanx, Lunesta, GF/CF diet, Lauricidin, oral IgG/lactoferrin/IGF-1 booster, gamma oryzanol, astaxanthin.

 I don't think you can assume that something in the same chemical family has the same effect or potency. Niacin does have antichlamydial effects, but I can tell you from experience that INH is a much more potent antichlamydial.

CAP for Chlamydia pneumonia since 11/04. 25yrs CFS & FMS- Currently: 300mg INH, 200 Doxycycline, 500mg MWF Azithromycin, 1000mg Tini daily (Taking a break from continuous protocol)

 

CAP for Cpn 11/04. Dx: 25+yrs CFS & FMS. Currently: 250 aithromycin mwf, doxycycline 100mg BID, restarted Tini pulses; Vit D2000 units, T4 & T3, 6mg Iodoral

John, I agree with Jim and Steve. We use vitamin B3 and INH together to fight cpn. http://www.cpnhelp.org/clearing_immune_cells INH is not a compound of niacin. Both are single ring chemicals. Isoniazid can cause vitamin B3 (niacin) deficiency through its impaired production from tryptophan. It interferes with cell-repair enzymes that use niacin. Barbara. Multiple sclerosis, on Wheldon protocol since February 2004, EDSS 0 for over 4 years

Cured of multiple sclerosis, stopped the Wheldon's protocol in Nov,2008. Use only LDN.

Barbara     

You're right, I mispoke/mistook that INH was a compound based off of Niacin.  More correctly and accurately, it's a compound that is very similar to Niacin in chemical composition.

The chemical formula for INH:  C6H7N3O 

The chemical formula for Niacin:  C6H5NO2

They're really not too different from a molecular composition standpoint but obviously very different in terms of their characteristics.  My only point was to point out their similarities and pose the question of whether or not one could substitute for the other, which it's clear to me now is not possible.   

all my best

John

RRMS/EDSS was 4.5, now 4.??? on Wheldon Protocol (nac, doxycycline, azithromycin, metronidazole) since 04/12/2006. Added Rifampin 2x150mg/daily on 08/19/2007

best, John

RRMS/EDSS was 4.5, 5, 6, 6.5, 6.9999, 6.5 on Wheldon/Stratton Protocol beginning 04/12/2006
nac 4x600 mg/day
doxycycline 2x100mg/day
azithromycin 3x250mg/day MWF
metronidazole 3x400mg/day then 3x500mg/day

John, We love ya, but will you knock it off!?!?! The instant you get semi-used to any change you've made to the protocol, you're already looking for something else to load up on and tinker with!!! Step away from the medicine cabinet... back up.... don't touch the drugs. Now, don't you feel better? Image removed.

The difference between what we do and what we are capable of doing would suffice to solve most of the world’s problems.  Mohandas Gandhi

The difference between what we do and what we are capable of doing would suffice to solve most of the world’s problems. Mohandas Gandhi

Actually Mac, I already have a prescription to INH that I'm intentionally not using.  I'm only asking out of curiosity.  I have already settled on a plan not to start taking INH until 3 months on Rifampin have passed.   So quell your fears, I'm not going to change anything right now. 

all my best

John

RRMS/EDSS was 4.5, now 4.??? on Wheldon Protocol (nac, doxycycline, azithromycin, metronidazole) since 04/12/2006. Added Rifampin 2x150mg/daily on 08/19/2007

best, John

RRMS/EDSS was 4.5, 5, 6, 6.5, 6.9999, 6.5 on Wheldon/Stratton Protocol beginning 04/12/2006
nac 4x600 mg/day
doxycycline 2x100mg/day
azithromycin 3x250mg/day MWF
metronidazole 3x400mg/day then 3x500mg/day

I have been unable to tolerate Niacin in high doses due to flashing.  I can only take 250 mg a day total, split in 2.

Peace

Ruth

CFIDS/ME 25yrs, FMS, IBS, EBV, Cpn, (insomnia - melatonin, GABA, tarazadone, temazepam, novocyclopine, allergy formula, 2 gm tryptophan), Natural HRT peri-M, NAC 2.5 gm, 6-07 Doxy 200 mg day pm, Azith 250 mg M/W/Fday, 8-21-07 1st pulse 1 X 250 mg Metro

CFIDS/ME, FMS, MCS, IBS, EBV, CMV, Cpn, H1, chronic insomnia, Chronic Lyme, HME, Babesia, Natural HRT-menopause, NAC 2.4 gm,Full CAP 6-2-07, all supplements+Iodorol, Inositol-depression, ultra Chitosan, L lysine Pulse#27 04-19-10 1gm Flagyl/day-5 days<