NAC versus Amoxicillin

In describing the work done at Vanderbilt, the CPN Handbook observes that Dr. Stratton used Amoxicillin.  Dr. Wheldon's protocol uses NAC.  I understand that both work on the CPn Elementary Bodies and that NAC is easier on intestinal flora as well as being protective of the liver.  That aside, are there co-infections that would be vulnerable to Amoxicillin but not to NAC?  Could the CAP be done with Amoxicillin rather than NAC?  Or with Amoxicillin in addition to NAC?  

hdwhit        

Wikipedia has information on amoxicillin and the micro-organisms that it targets or those that are resistant.  I don't know that this is necessarily a complete list but it probably covers the majority of known organisms involved.

http://en.wikipedia.org/wiki/Amoxillin

The same source when consulted on NaC doesn't expressly list any organisms although it makes mention of influenza and also free radicals.

http://en.wikipedia.org/wiki/N-acetyl_cysteine

best, John

RRMS/EDSS was 4.5, 5, 6, 6.5, 6.9999, 6.5 on Wheldon/Stratton Protocol beginning 04/12/2006
nac 4x600 mg/day
doxycycline 2x100mg/day
azithromycin 3x250mg/day MWF
metronidazole 3x400mg/day then 3x500mg/day

HD to these 2 questions, Could the CAP be done with Amoxicillin rather than NAC?  Or with Amoxicillin in addition to NAC?   My understanding would be to say yes to both.

Then I would say that the adverse reactions to Amoxicillin (taken over long term) might be something that I would want to avoid. Diarrhea is most common, Google the drug and find all the others that are listed here in my Drug Guide 2005 hard copy. 

Louise

  • CAP(TiniOnly): 06/07-02/09 for CFS
  • MethylationProtocolSupplements: Started08/08
  • Intermtnt CAP: 02/09-02/10
  • Full MethylProtocol & LDN 02/09
  • Off CAP: 02/10, cont LDN & MethlyProtocol support

Adding amoxicillin might make it more affective against lyme. Amoxicillin also targets lyme with a different mechanism than doxy, zithro and metro.  Maybe not worth the risk  since it could cause as mentioned above but maybe some could tolerate it ok, I dont honestly know.

 

 

 

 

 

&nbs

It certainly has been done with amoxi, as that was what Dr. Stratton used originally, along with a drug to keep it in the blood stream longer. I initially used it prioe to following Dr's Wheldon and Powell when they came up with their recommendation for using NAC instead. It truly did upset bowel flora for me, already problematic with my candida tendencies. I've also heard it used in Lyme's so it might be a useful combo in co-infections with Cpn. Dr. Stratton has recently recommended that, prior to going on intermittent therapy at the end of one's protocol, using amoxi for a month or so to assure "clean up" (my words) of EB's.

 

CAP for Cpn 11/04. Dx: 25+yrs CFS & FMS. Currently: 250 aithromycin mwf, doxycycline 100mg BID, restarted Tini pulses; Vit D2000 units, T4 & T3, 6mg Iodoral

Yes Jim, using it for one month prior to moving to the intermittent phase of therapy would be a good option to take advantage of the benefits without the disadvantages in bowel disturbance that is all to common with extended use of this medication.  I'll keep this possibility to discuss with my MD when the time comes for me to make that switch.

  • CAP(TiniOnly): 06/07-02/09 for CFS
  • MethylationProtocolSupplements: Started08/08
  • Intermtnt CAP: 02/09-02/10
  • Full MethylProtocol & LDN 02/09
  • Off CAP: 02/10, cont LDN & MethlyProtocol support