NAC for Cpn - literature ?

Does someone know if the recommendation to take NAC against Cpn is backed up by scientific literature (e.g. journal papers). Could you point me to some sources? Or is the recommendation just based on empirical observation?

Hi Markus,

I don't think there is any literature. And I am not completely in agreement with some here on why it is beneficial. I belive that NAC does exactly what it is well known to do, replenishes cellular glutathione. It is believed that glutathione breaks down disulphide bonds that hold elementary bodies together so they can begin replication. So in the event that glutathione were depleted in host cells (I would guess this could happen in chronically infected cells as glutathione is used up in breaking down disulphide bonds.), you might have a larger than normal population of EB's in the host cell. This would be undesireable in the event a cell undergoes apoptosis or necrosis as there would be more EB's available to infect nearby cells.

- Paul

D W

Markus

As far as I am aware there is no published literature on the activity of NAC against the elementary bodies of C. pneumoniae. However, Dr Stratton, an acknowledged expert on C pneumoniae infection, commented in a 2009 statement concerning the treatment of chronic infections with this organism:

 

“I would add NAC to the supplements. We used amoxicillin, which is degraded in the body to penicillamine (a reducing agent) in our regimen as an anti-elementary body agent, but NAC seems to work equally well and may offer additional benefits in boosting the immune system as well as protecting the liver.”

D W - [Myalgia and hypertension (typically 155/95.) Began (2003) taking doxycycline and macrolide and later adding metronidazole. No medication now. Morning BP typically 110/75]

i wonder if some of the nourishing traditions seen across various cultures have been protecting populations against CPn. If the sulfur content of NAC breaks disulphide bonds in EB forms of cpn, could cruciferous food stuffs be having a similar effect! Im thinking sauerkraut which is consumed daily across much of europe, and kimchi in korea...

---------------------------------------------------------------------------------------------------------------

Doing Thibault protocol (NAC/mino/roxi/tini/nattokinase)...but considering morphing to Stratton protocol

Terry Wahls is definitely aware of the link between cpn and MS. If you read her latest book, you'll notice she recommends using a prolonged antibiotic protocol if your MS is not brought under control using diet alone

---------------------------------------------------------------------------------------------------------------

Doing Thibault protocol (NAC/mino/roxi/tini/nattokinase)...but considering morphing to Stratton protocol