Mycoplasmas as Important Infections in Chronic Illnesses

I found this article online. I am not questioning any of the doctors protocols but why is this doctors protocol a little different. I tested positive for cpn but what is I have a combination of mycoplasma infections such as Mycoplasma genitalium do I need to change to the protocol below (in bold) or will Dr. Wheldons protocol work for all Mycoplasma infections?

 

 

Mycoplasmas as Important Infections in Chronic Illnesses

Although most mycoplasmas are not considered important human pathogens, some species, such as M. fermentans, M. penetrans, M. pneumoniae, M. genitalium, M. pirum and M. hominis, among others, have been closely associated with various human diseases [7]. This does not necessarily mean that these diseases are entirely caused by mycoplasmal infections but this type of infection is important in causing much of the morbidity or illness seen in patients with chronic illnesses.

Do FMS, CFS, RA or GWI patients show evidence of mycoplasmal infections? In a majority of FMS, CFS, RA and GWI patients examined we and others, principally Dr. Daryl See of the University of California College of Medicine, Irvine, CA, are finding strong evidence for mycoplasmal blood infections that can explain much if not most of their chronic signs and symptoms. In our studies on GWI, a CFS/FMS-like condition [1], we have found mycoplasmal infections in about one-half of approximately 400 patients, and these patients were found to have principally one infectious species, M. fermentans [8, 9]. Moreover, in over one-half of the 500 civilians with CFS, FMS or RA that we have examined we are finding a variety of pathogenic mycoplasma species, such as those listed above, in the leukocyte fractions of blood samples. The tests that we use to identify mycoplasmal infections, polymerase chain reaction and nucleoprotein gene tracking [10], are very sensitive and highly specific. These tests are a dramatic improvement over the relatively insensitive serum antibody tests that are routinely used to assay for systemic mycoplasmal infections. In fact, we have received a Department of Defense contract to train scientists and physicians to conduct these tests, and in the second week of January 1988 a group, including staff from the Armed Forces Institute of Pathology and Walter Reed Army Medical Center, the University of Texas Medical School at San Antonio and the University of California, Irvine School of Medicine, will be arriving at the Institute for Molecular Medicine for advanced training in mycoplasma detection in blood and other body fluids.

New Treatments for Chronic Infections Found in FMS, CFS, RA and GWI

The identification of mycoplasmal infections in the leukocyte blood fractions of a rather large subset of CFS, FMS and RA patients suggests that mycoplasmas, and probably other chronic infections as well, may be an important source of morbidity in these patients. If such infections are important in these disorders, then appropriate treatment with antibiotics should result in improvement and even recovery. This is exactly what has been found [11]. The recommended treatments for mycoplasmal blood infections require long-term antibiotic therapy, usually multiple 6-week cycles of doxycycline (200-300 mg/d), ciprofloxacin or Cipro (1,500 mg/d), azithromycin or Zithromax (500 mg/d) and clarithromycin or Biaxin (750-1,000 mg/d). Multiple cycles are required, because few patients recover after only a few cycles [9], possibly because of the intracellular locations of mycoplasmas like M. fermentans and M. penetrans, and the slow-growing nature of these microorganisms. These responses are not due to placebo effects, because administration of some antibiotics, such as penicillins, resulted in patients becoming more not less symptomatic.

Treatment recommendations for mycoplasmal infections are similar to those used to treat Lyme Disease, caused by other slow-growing intracellular bacteria that are difficult to identify and treat. Interestingly, FMS, CFS, RA and GWI patients that recover after several cycles of antibiotics are generally less environmentally sensitive, suggesting that their immune systems may be returning to pre-illness states. If such patients had illnesses that were caused by psychological or psychiatric problems or by environmental or chemical exposures, they should not respond to the recommended antibiotics and recover their health.

I have tested positive for cpn as well as myco. my doc said that the protocol (NAC, doxy or mino, azith or biaxin, and flagyl or tini) will reach cpn as well as myco.  

Mphs, TN. CFS, hypoT (Hashi), adrenal fatigue, 37 w/hormones of 80,. right arm neuropathy. + cpn, myco, EBV, CMV. NAC 4000mg, doxy 100-2xday, azith 250 m/w/f/sun, progesterone, estriol, synthroid, pulse flagyl, tini<

Mphs, TN. CFS, hypoT (Hashi), adrenal fatigue, hormonal inbalance. right arm neuropathy-getting better. cpn, myco, EBV, CMV, HHV-6. Cap began in 6/07. NAC 2400mg, mino 100mg bid, biaxin 500mg bid. cytomel, flagyl bid continuously.

Lee,

Would you please provide information to whom the author of this article or paper is and the date it was written? TIA Image removed.

3/08 NAC 2400 mg, 4/08 Iodoral 25 mg, 5/08 mino 100mg, 6/08 Zith 250mg 1/wk, myco+ CFIDS/FMS, Hashimoto's, Psoriasis, PA, IBS, Secondary Addison's

When I change what I believe I change what I do

NAC 2.4g, Zith 250mg/MWF, mino 200mg, Tini 5day/1g/5 pulses, Valcyte
Supplements, CFIDS/FMS, Hashimoto's, Psoriasis, PA, IBS, Sec Addisons

Don't believe everything you think!  

Can't tell you why this unknown author has a different protocol, but I can tell you that, without metronidazole or tinidazole, it's incomplete. And why cycle the meds and enhance your chances of the bacteria developing resistance?

The difference between what we do and what we are capable of doing would suffice to solve most of the world’s problems. Mohandas Gandhi

The difference between what we do and what we are capable of doing would suffice to solve most of the world’s problems. Mohandas Gandhi

This sounds like Garth Nicholson to me. The protocol he mentions seems to be geared towards mycoplasma not cpn. A CAP procotol should work for both Cpn and mycoplasma, where as as Mac says the above protocol is only likely to work for mycoplasma.

CFS. Started CAP 03-07. Currently: Roxi 600mg + Doxy 200mg . Tini pulses 1000mg. Sauna QOD. D 8000IU. Niacin 3 x 500mg. Mel 3mg.

Hunter: Don't think - experiment

Lee- You do understand that Cpn has to be treated with agents for each of the three phases the organism can survive in? Mycoplasma, while difficult to treat, does not seem to phase shift in this way and so is treated via monotherapy. Where the Cpn CAP can treat Mycoplasma, a Myco regime cannot fully treat Cpn. Dr. Nicholson does not seem to be aware of the multiple phase nature of Cpn and recommends monotherapy courses.

Lee, I don't wish to discourage your enthusiasm here in posting, but from my perspective it seems that you came onto the site doing a lot of posting of ancillary treatment information and questions like this make me think you've done too much output and not enough input, i.e. reading and absorbing the information about Cpn here. I appreciate your interest in being engaged with and contributing to the community, but I'd suggest you absorb a bit more information before rushing to post. 

CAP for Cpn 11/04. Dx: 25yrs CFS & FMS. Currently: 300mg BID Roxithromycin, Bactrim DS 2x/day, Tini 1000mg/day pulses; Vit D2000 units, T4 & T3

 

CAP for Cpn 11/04. Dx: 25+yrs CFS & FMS. Currently: 250 aithromycin mwf, doxycycline 100mg BID, restarted Tini pulses; Vit D2000 units, T4 & T3, 6mg Iodoral

Mac,

I agree, in that whether or not the D deprivation of the MP caused me to test positive for a mycoplasma infection now by weaking my immune system and making me susceptible to it (read that in an article about D deficiency) or I had it all along, something was incomplete or caused me to relapse.  IMO, it may have been a combo of factors one being I wasn't treating all phases/life cycles of what was infecting me, so to sum it up...

Even if one has a co-infection of myco or only tests positive for myco, one may (and the evidence points most likely) have CPn infection also and it would be best and most wise to use the CAP approach here to eradicate all life cycles of the bugs making one sick!  

Garcia,

That is what I thought too in that the info sounds like Garth and I believe it's quite old or at least not as current as what we have here on this site and in the journals about chronic Chlamydia Pneumoniae causing alot of these illnesses and how to treat it.  

Lee,

When one's own immune system is working properly again by eradicating the main cause of infection, the body will heal and deal with any other infections that may be secondary or less severe such as fighting off viruses (ie; EBV, HHV6, CMV) as is discussed on David Wheldon's and Dr Powell's sites.  Image removed.

3/08 NAC 2400 mg, 4/08 Iodoral 25 mg, 5/08 mino 100mg, 6/08 Zith 250mg 1/wk, myco+ CFIDS/FMS, Hashimoto's, Psoriasis, PA, IBS, Secondary Addison's

When I change what I believe I change what I do

NAC 2.4g, Zith 250mg/MWF, mino 200mg, Tini 5day/1g/5 pulses, Valcyte
Supplements, CFIDS/FMS, Hashimoto's, Psoriasis, PA, IBS, Sec Addisons

Don't believe everything you think!