My Adrenal Fatigue Cure

Submitted by biohazard on Tue, 2008-09-30 21:19

I have come up with a cure for Adrenal Fatigue that I've been very successful with. I have suffered from CFS/Adrenal Fatigue for 5 years. Saliva Test showed high morning cortisol (morning response) with low @ lunch, dinner and bedtime. Recent Thyroid bloodwork showed a very low-normal DHEA-S.

I have had symptoms of very low cortisol. I have tried Isocort which helps sometimes and sometimes doesn't. At times it has brought my low body temperature back to normal within 15 minutes. I also have ear drops with HydroCortisone. A few drops on the skin will transfer a decent shot of HC. This stuff has saved me when I was too wiped out to get out of bed. And I've tried with limited success the usual supplements like B5, Sea Salt, Vitamin C, Ashwagandha, Maca, Siberian Ginseng, Adrenal Cortex Glandular, Licorice. I think the Vitamin C has been the most helpful of that bunch and perhaps Licorice Tea.

I found my cure after taking one of Jarrow's B-Right B Complex capsules. I took about 1/5 of the capsule and felt very much improved within 10-15 minutes. I knew one or more of the ingredients in the capsule was helping me greatly. I was able to repeat this success over the next few days. Since I already had and was taking most of the separate B vitamins, and Folic Acid and Choline I focused on the two in the vitamin that "B-Right" contains that I didn't have: PABA and Pantethine.

I've researched these two extensively. The PABA especially is supposed to be able to potentiate cortisol, perhaps similar to what licorice does perhaps but much much better. The Pantethine provides some raw materials for hormones and is huge for production of Co-Enzyme A and seems to be synergistic with the PABA.

I start by taking 100mg of both per day at about 9 AM. The PABA is very caustic, I dump out about 1/5 of the cap under my tongue then wash down with water, then again (it will get stuck in your throat). You might try a PABA tablet if you prefer or buy empty caps and fill them. The Pantethine is an oil caplet. This one is easy. I puncture the cap with a push pin or "map tack" then squeeze out about 1/5 of the caplet onto my tongue (tastes fine). Then put the caplet away for the next day. The caplet will seal itself by the next day.

The first day I took these I was still going at 10pm and felt like I could go to the gym at that time. I was amazed. The next day I felt fine. No cortisol hangover. My body did not make less cortisol to compensate. I attribute that to taking a small dose. I would recommend you take the smallest dose of each that provides you just enough energy so when bedtime comes you are ready.

This has worked for myself and at least one other who had the beginnings of Adrenal fatigue after a viral episode and heavy stress. She had severe fatigue and would have a cortisol crash during the day, feel better after eating, etc. Most of the symptoms I've come to be very familiar with after 5 years. I put her immediately on the PABA/Pantethine and she recovered quickly enough to return to the gym after a week. 

Here are links to exactly what I've been taking:


Jarrow Pantethine

If you use then use the following referral code and get $5.00 off your first purchase: HAW103



Have you had your adrenal function remeasured showing normal limits?  If not, I would caution you stating you've found a "cure" and maybe have found a temporary quick fix to aid you.  I think it's important when sharing this information on an open forum especially since I'm sure no one here wants to make any false claims, including you.   

Thanks for sharing your info.  I would definitely like to know what your test results are now.  Image removed.

As I've previously stated, I was properly diagnosed and treated for Secondary Addison's disease which was triggered by stress and the use of steroids for allergies and psoriasis.  It took about a year of support using an rx non-steroidal type of cortisol replacement and careful weaning and monitoring by a reliable endocrinologist and rest but my adrenals fully recovered. This happened to me nearly 2 decades ago. 

The fact that this happened to me at all shows I have delicate adrenals but they do work properly now and I do use supplements which tend to support the adrenals like Vit C, B and I've recently started taking Drenamin again which I used last year. 

There are muscle tests one can do with someone trained in Applied Kinesiology (my chiropractor does this) and clues to sub clinical weakness such as pain or spasm in certain muscles which I have from time to time like in between meals when the adrenals are being stressed, so I think it wise to do all one can to aid the adrenals during CAP which causes stress on the system by fighting infection.  I think that's why it's so important to take the supplements recommended HERE.      

From what I read in Dr Powell's patent relating to human dormancy syndrome, it seems that excess cortisol also causes the thyroid to work less efficiently so I think it's prudent and wise for folks to be aware of what is happening to their thyroid during chronic illness and CAP as well as many folks on this site are doing.  

NAC 2.4g, Zith 250mg/MWF, mino 200mg, Tini 5day/1g/5 pulses, Valcyte
Supplements, CFIDS/FMS, Hashimoto's, Psoriasis, PA, IBS, Sec Addisons

Don't believe everything you think!  

Reenie - I understand your caution and skepticism.

I call it "My" cure because it works for me. It was truly a remarkable find for me. Now that I've seen it work just as well in someone else I have posted about it in a few places hoping others who have adrenal insufficiency might try it and hopefully benefit as much as I have.

I've been my own lab rat for 4+ years. I pray that all the pain and suffering I have gone through can help someone else avoid it.

I have had the 4x per day saliva cortisol test done and showed a high morning response then at the lowest point or below @ lunch, dinner and PM. I saw a thyroid doc last week and he has requested another test of the same.

I've read about many who take a year or more to restore the adrenals. I imagine it's inconceivable that something can work within a few days. The Paba/Pant combo seems to immediately correct the insufficiency and allow the adrenals to heal at the same time.

Perhaps I don't have the same type of adrenal fatigue. I respond to hydrocortisone when I feel my adrenals are fatigued. I respond to licorice if I don't take it every day but only a fraction of the help I get from the Paba/Pant.

I don't know if there is a down side yet. I haven't had to take this for more than 3-4 weeks at a time. I'd attempt mercury chelation with Chlorella or Pectasol and my adrenals get wiped out and I'm back on the Paba/Pant. I would get psychologically stressed, adrenals depleted, back on the Paba/Pant.

Many who chelate use HC when their adrenals get stressed.

I agree too much cortisol is a bad thing. I don't know if this is an adaptogenic response or it is a dose dependent response to the vitamins. Which is why I take and am recommending the smallest dose that produce the desired effect. (I recommend that with any medicine or supplement).

Again as someone who has tried most/all of the Adrenal supplements and only had marginal results (with perhaps the hit or miss response of Isocort) I was amazed at what this combination did for my adrenal fatigue.



Doxy 100mgx2, Azithromycin 250mg MWF, Probiotics: PB8, JarrowDophilus. CFS since 2003. Last 5+ years lots of the usual research (Depression, Adrenal Fatigue, HPA, Mercury, Candida, Thyroid, etc.). $5 coupon code: HAW103

Hi Bio,

what is the current status regarding your adrenal fatigue? does the combo still work?

I have a low cortisol in 8AM, only 11 and I guess I have adrenal fatigue but my french doctor does not want me to do saliva test as I am in the normal range and adrenal fatigue is not recognized in France :-(

My adrenals are in decent shape, I currently don't take the PABA/Pantethine combo (don't feel I need it) but I can make it to the gym most of the time I want to go. I can seriously deplete cortisol by weight training. I have to stop before I get too depleted. Sometimes taking a IsoCort or two helps me get through a tough workout.

Note: Pantethine is NOT the same as Pantothenic Acid. The latter must go through an enzymatic reaction to become the former. Much like P5P is not the same as B6.

Doxy 100mgx2, Azithromycin 250mg MWF, Probiotics: PB8, JarrowDophilus. CFS since 2003. Last 5+ years lots of the usual research (Depression, Adrenal Fatigue, HPA, Mercury, Candida, Thyroid, etc.). $5 coupon code: HAW103

Adrenals --  Since this popped back up it came to my attention.  Bio, your using Pantethine to treat adrenals isn't really new.  Many holistic doc's are aware of using Pantethine. 

I have treated my adrenals off and on since the year 2000 with a product given to me by my doc back then. It's called Adapt made by InterPlexus.  Have you tried it?  They also have a "counter" product called Seriphos to  balance out Corisol levels naturally in the body.  Both work quickly and help heal the adrenals.

Unfortunately, the fact I don't have a thyroid (causing my adrenals to exhaust) and the infiltration of CPN, pushed my body to the point of needing  to add Cortef.

Here are the ingredients of Adapt :

Vitamin B6 ...25mg
(as pyridoxine HCL)
Biotin ...1, 000mcg
Pantothenic Acid ...250mg *****
(as calcium pantothenate)
Zinc ...5mg
(as malate)
Copper ...500mcg
(as citrate)
Proprietary Blend ...320mg
Extracts of Rosemary, Ashwagandha, & Hesperidin Methyl Chalcone


I, too, am curious, how your adrenals are doing.... MacWanted you may wish to give Adapt a try as it is safe and proven.




JeanneRoz ~ DX'd w/ CPN 4/2007; 6/07 -"officially" dx'd w/CFIDS/FM; also: HHV6, EBV, IBS-C, 100 Doxy:BID; 500 mg Biaxin BID; Tindamax Pulses, B12 shots, ERFA Dessicated Thyroid,Cortef, Iodoral 25 mg, Vit D-6,000 uni