Minocycline

Is Minocycline just as good to use as Doxycycline for CPn?

 If so, what dose?

 

As good, but there are more side effects, in addition as those which you tend to get with doxycycline, which is why doxy is preferred for long term use.......................Sarah    
    
A Journey through Light and Shadow
Completed Stratton/Wheldon regime for aggressive secondary progressive MS in June 2007, after four years, three of which intermittent.   Still improving bit by bit and no relapses since finishing treatment.

I used doxy for 1 yr or 1 1/2 yrs and then switched to minocycline.   It took me full 6 weeks to ramp up to minocycline at 100mg twice a day. My porphoyria was very bad during the 6 weeks.  I'm not sure why though.  It was a rough 6 weeks, but 2 yrs later, i'm still on minocycline. 

Mphs, TN. CFS, hypoT (Hashi), adrenal fatigue, hormonal inbalance. right arm neuropathy-getting better. cpn, myco, EBV, CMV, HHV-6. Cap began in 6/07. NAC 2400mg, mino 100mg bid, biaxin 500mg bid. cytomel, flagyl bid continuously.

So dose for dose it seems that the Minocycline is more effective, or packs more of a punch.....is that right?

I just have a couple of bottles of Mincycline and don't want to waste them. 

I am thinking of starting Minocycline myself and am curious to the same questions mentioned.

Sharon, was their a reason you wanted to switch from Doxy. to Mino.?

I was reading of the anti inflammatory properties of Mino. and I read it works very well for lyme.

started Wheldon cap 4/21/08 for Cpn, CMV, EBV, CFS. Cap hold 4/09vascultis. Restart 9/09 with Dr.Powell, restore gut, 4000 D3, supplements,  Pos. Bartonella and Babesia, Rifampin 600 mgs and Biaxon 1 gram. 

I switched b/c I was no longer having any reaction from doxy and clarithromycin, and maybe even felt like I was back sliding a little bit. I wanted to switch things up a bit, so i stopped the doxy and started minocycline.  

 For me, minocycline fit easier into my schedule. I like to take my antibiotics on empty stomach and first thing in the morning.  I couldn't do that with doxycycline.   I get so nauseated from doxy that I had to take it after i ate. 

  Annelet.. I cant say for sure that mino is more powerful in general.. The doxy never caused me porphoyria and the mino did. trying to ramp up to mino at twice a day was like doing a 6 week flagyl pulse.  I can't explain why.   

 I also thought that i remember reading somewhere that mino has better BBB penetration  than doxy.. but i dont know for sure ..maybe medical minded person can shed some light on doxy vs. mino. 

Mphs, TN. CFS, hypoT (Hashi), adrenal fatigue, hormonal inbalance. right arm neuropathy-getting better. cpn, myco, EBV, CMV, HHV-6. Cap began in 6/07. NAC 2400mg, mino 100mg bid, biaxin 500mg bid. cytomel, flagyl bid continuously.