Metro pulse

i've finished pulse 2, it was more difficult than the last and I'm sure it'll get harder still, but I'm wondering if I should take pulse 3 sooner than 3 weeks? Does anyone know if it would be beneficial? I am noticing small improvement.

Please go slowly.  Pushing too hard means your body doesn't have the time or the ability to purge what you've killed off or to recover from the inflammationi the die-off causes.

The difference between what we do and what we are capable of doing would suffice to solve most of the world’s problems. Mohandas Gandhi

Jane, just keep in mind the fact that the first and only Vanderbilt trial including metronidazolei was stopped early because too many people dropped out:  taking  metro every day was too  much for them. That is why David decided to pulse..........Sarah 

Completed Stratton/Wheldon regime for aggressive secondary progressive MSi in June 2007, after four years, three of which intermittent.   Still improving bit by bit and no relapses since finishing treatment.

Yes – take it slowly. Metronidazolei and related agents work by causing single stranded breaks in the bacterial DNA. When a critical number of breaks occur, the bacterium dies, releasing endotoxini. You want to control the rate of release in order to avoid host damage.

 

There is no danger of the bacterium becoming resistant. Although bacteria can repair DNA breaks, they need numerous enzymes to do so. Doxycycline and macrolides prevent the bacterium from synthesizing these necessary enzymes. So the bacterium is doomed. But let its doom come slowly and steadily.

D W - [Myalgia and hypertension">i (typically 155/95.) Began (2003) taking doxycycline and macrolide and later adding metronidazolei. No medication now. Morning BP typically 110/75]

Thanks Mackintosh,

Good advice, my body is saying that last pulse knocked it around a bit and you're saying it knows best! 

Jane

MSi symptoms from 2001, DXi RRMSi in 2008, following, a change of hospital who sent me for an MRI, precipitated by some sight loss. Took Interferons, on and off. Prescribed  chemo infusions to slow pro

Thanks DW and Sarah, I am trying to go too fast, those small improvements don't really make me a Superwoman! That comes much later!

Jane

MSi symptoms from 2001, DXi RRMSi in 2008, following, a change of hospital who sent me for an MRI, precipitated by some sight loss. Took Interferons, on and off. Prescribed  chemo infusions to slow pro

But the main thing is - don't give up.  You are correct - it will knock you down and around.  You can outlast it.  I did, and every day I wake up happy and relieved that I did.  Also every day, I can do things a tiny bit better.   I am stronger, walk a little better, and think a little better.  Yes, it is hard, but so, so worth it

Rica

3/9 Symptoms returning. Began 5 abxi protocol 5/9 Rifampin 600, Amox 1000, Doxyi 200, MWF Azith 250, flagyli 1000 daily. Began Sept 04 PPMSi EDSSi 6.7 Now good days EDSS 1 Mind, like parachute, work only when open. Charlie Chan  In for the duration.&am

You inspire me Rica.

jane

MSi symptoms from 2001, DXi RRMSi in 2008, following, a change of hospital who sent me for an MRI, precipitated by some sight loss. Took Interferons, on and off. Prescribed  chemo infusions to slow pro

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