hdwhit 29 Apr 2011 12:45 am Do an internet search for Do an internet search for Rich Van Konynenburg and some part of the title of the article "...Glutathione Depletion - Meythylation Cycle Block Pathogenesis Hypothesis...". Rich is a PhD, not an M.D. and he's dealing with CFS, not MS, but if we believe CpN causes both, the treatments should have similar effects. I have not tried anything he suggests other than switching my vitamin B-12 supplement from cyanocobalmin to methylcobalamin. Some days it seems to make a difference, other days it doesn't, so I don't know if there's anything to it, but the paper is reasonably understandable by a layman. Whether anything it says is true is another matter. CAP for M.S. 8/2007 - 3/2009. Twentieth pulse metronidazole + INH completed 3/12/2009. Intermittent treatment thereafter until 11/20/2009.