Ketogenic diet that really helped for CFS
I have had chronic fatigue, which I believe to have been caused by Cpn (positive IgG test) - and recently re-tried a ketogenic diet because I was really sick and had no access to any other treatment at the time. I had tried (what I thought were) ketogenic diets before, but this time things were made much easier because I bought some test strips - which actually indicated wether I was in ketosis and ate lots of MCT oil (which forces the body to produce ketones). A proper ketogenic diet made a huge difference for me. I was seeing a counsellor at the time and he could not believe the difference that the change in diet made for me - it was pretty extrodinary. Of course diet alone cannot get rid of Cpn, antibiotics are needed to kill the pathogen, but I think diet + antibiotics might really help some people. PaulJ on this forum followed that approach (his perfect health diet site is linked below) and seems to be completely better from chronic fatigue. I am not sure whether the approach would help MS patients - but because it had such a profound effect on my neurological well being, I think it might.
I can't claim to know nearly as much about Cpn or biology as most of the people on this site, but I have read (in Paul Jaminet's -PaulJ on this site - Perfect health diet book) that brain cells can metabolize only glucose and ketones (not fats) so to me it seems like changing the fuel of the ATP generation in our cells to something different, might have a good shot at disrupting Cpn. Ketosis occurs naturally mostly during starvation, and it seems like it would be a bad idea for a bacteria like Cpn, which depends on a living host, to evolve to infect starving animals...
This very detailed blog series (by a former MD - unfortunately with a focus on physical performance rather than theraputic diets) discusses the chemistry of ketosis in detail:
Glucose is often actively transported into cells and Cpn seems to mess with cellular transport mechanisms a lot - diverting a lot of useful goodies to itself by taking over the golgi apparatus (the cell's equivalent of a distribution hub). I think (again from Paul Jaminet's book) that ketone transport occurs by diffusion alone. Ketogenic diets have been known to help some neurological conditions (particularly epilepsy) for a long time - and there are quite a few people with a range of conditions who have reported being helped by the ketogenic diets of various kinds (perfect health diet, GAPS diet, specific carbohydrate diet are some that I have come across - but note that many of the diets don't really explain how to properly implement a ketogenic diet).
OK so that is why a ketogenic diet might help - how to implement one? There are basically 2 ways to do it - to force the body to make ketones by eating an atypically high amount of medium chain fatty acids, or to restrict carbohydrates and add more protein to the diet to mimic starvation. Mimicing starvation seems like a bad idea if you are sick, so the extremely low carb ketogenic diets don't seem like a great idea to me - leaving the 2nd option. These 2 blog posts give some background on the 2 approaches:
What I do is restrict carbohydrates a little (I eat about a 1/3 of a plate of rice or 3/4 of a baked potatoe per day, with dinner) and then eat mostly meat and vegetables for my other foods (typically a British style cooked breakfast and a salad with protein of some kind for lunch and then carbs + meat + veg for dinner). I also cut out refined sugar (sucrose) as much as possible - and try to limit fructose consumption (I eat banans for fruit mostly - which have less fructose than many other fruits). But the key for me to get ketosis working properly (and actually be able to think) was consuming a lot of medium chain fatty acids, by taking a lot (around 9 tablespoons) of MCT oil a day. MCT oil is a health food product - derived mainly from coconut and palm oil (recently I found that getting stuff made from coconut oil exclusively helped me with some digestive discomfort). I only just started antibiotics (literally last night) so the combination of the two is not something I can really comment on. Taking this oil was the key for me getting a ketogenic diet to work - I tried eating less carbs previously but ended up feeling really ill - and had to stop. Apparently your body doesn't use medium chain fatty acids for much else other than making ketones - so flooding your liver with them results in a high level of ketones in your blood. MCT oil is a bit hard to take (not nearly as bad as consuming an equivalent quantity of coconut oil) but having it with coffee (decaf for me - called bulletproof coffee sometimes - after a paleo blogger) seemed to do the trick (I can take up to 3 tablespoons in one cup). When I started I regularly tested my blood ketone level using urine test strips - such as these which can be easily ordered online:
Using the test strips and being able to add more or less ketones easily by changing the MCT oil dose (note I am a 6 foot tall 160lb male) was a breakthrough for me in getting into ketosis.
OK I have shared what I know about this stuff now - which is rather incomplete but at least the links will give the more medically sophisticated folks an entry point. I am hugely grateful to this community for providing so much helpful info about Cpn - without which I would almost certainly have never been properly diagnosed (happened yesterday for me). I am very 'time-energy' limited (like most people I guess) so I will probably post infrequently on this site and hopefully read the new posts more often. I still have a lot to learn about Cpn - but you folks have provided me with some very helpful entry points and I am sure much more useful info in the future. I hope that this post is of interest/help to some.
If you want to read more about diet I recommend Paul Jaminet's book - 'The Perfect Health Diet'. and his blog http://perfecthealthdiet.com/. Please do feel free to contact me if you are interested in this diet approach - I am busy but I will take time to help anyone here that I can - I have really appreciated the help from others on this site.