I spent a couple of hours this evening trying to figure out what an intermittent protocol might look like - and finally found the details in Sarah's story on David's website. Thought I'd re-post to save others the trouble if they are using the search on this site.
"Sarah stopped the continuous antibiotics two months ago. Improvements continued after they were stopped. We have decided to give a discontinuous maintenance therapy of 14 days doxycycline 200mg daily and roxithromycin 300mg daily*. Metronidazole, 400mg three times a day, is given for the final five days. This maintenance schedule is to be repeated at two month intervals."
*If roxithromycin is unavailable, azithromycin may be used. Rifampicin is not suitable for intermittent use.
I have some questions with respect to intermittent therapy, as I'm unsure that my doctor will support antibiotics indefinately. I wonder if anyone can help.
Are there other standard CAP intermittent schedules?
Do people 'take a break' from continuous antibiotics with a period of intermittent therapy? Is this advisable?
On this site people have been on CAPs for fairly short (1 year or so) to much longer times e.g. 5 years or more. I still feel worse when pulsing - generally more tired, more easily upset and usually experience bad asthma (which is a side effect of tinidazole - the antibiotic I pulse - but I guess it's possible that the side effect is a result of killing CPn). Is there a way to tell if its time to go intermittent? Does it differ for MS or ME/CFS? I have heard it said that CFS sufferers often have a higher CPN load.
Is there a practicing expert that my doctor (a PCP/GP) could ask questions of? I know of Stratton (I heard it is hard to reach him now) and D W (now deservedly retired). The ME/CFS center at Stanford used to have information on CPn (https://web.archive.org/web/20170228000756/http://med.stanford.edu/chro…) but now does not - I am not sure if anyone has experience with them. Is there anyone else with specialist experience on CAP?
OK maybe that's enough questions for one post .