MediTest
27 Apr 2018
Author
Louise
Title

Protocols a listing of treatments from the Getting Started Tab Page

Body

Well at the time that this is being posted 4/2012,the page under the getting started tab has had a shift in format (during a upgrade of this website).  This make is impossible to read.  I have sorted out to the best of my ability that which was posted there and am referencing it to the Bookmarks Forum to be located in the future by those that want to look at this topic.P.S.

Comments

This is the webpage in question take a look.http://www.cpnhelp.org/treatment_protocolsHere is what it seems to say when I sort it out.Treatment Combined Antibiotic Protocols Below are a number of different protocols as recommended by Drs Stratton, Sriram of Vanderbilt University and Dr WheldonUKconsultant microbiologist. These protocols are constantly being adjusted and you might find that some patients are following a different one from you. To a certain extent the protocol you follow depends on your Cpn load, and because that is often an unknown in the beginning of treatment we recommend that you start with Dr Wheldon’s protocol (unless you or your physician have consulted a doctor familiar with the treatment of Cpn).Wheldon ProtocolDoxycycline 100mg Once a day Take this alone until well tolerated.Add either one or the other of these to the 100mg doxycycline you are already taking, Azithromycin 250mg  Mon, Wed, Fri or Roxithromycin 150mg, Twice a day, everyday. When both the above are well tolerated add another 100mg of doxycyclineThen after the increase to Doxycycline 100mg Twice a day, Add the Metronidazole pulse, 400mg or 500mg depending on dose available in your country Three times a day (also called Flagyl).  When the first two antibiotics are well tolerated start pulsing the third. For one day every three to four weeks initially.   Increase the number of days per pulse gradually to five days.  As an alternative to the metronidazole used in the pulses, Tinidazole 500mg,Twice a day may be substituted.When the protocol is well tolerated Doxycycline and Azithromycin (or Roxithromycin) are taken continuously as outlined above. They prevent Cpn from replicating as well as killing it slowly (these antibiotics are called bacteriostatic antibiotics). After three or four months of these two antibiotics you can start pulsing the third antibiotic Metronidazole or Tinidazole.Definition of a pulse: Think of a cycle of treatment as a period of time. How long that period is depends on how well you are coping with the Combined Antibiotic Protocol (CAPi), usually this cycle is three or four weeks long. Once during this period of time you take Metronidazole (or Tinidazole) for a period of up to 5 days at the full dose. In the beginning of your treatment the pulse may be only one day long, as you tolerate the CAP you can increase the number of days you take the Metronidazole. Well into the treatment you may want to increase the number of days you take Metronidazole (or Tinidazole) beyond the 5 days recommended.The reason behind a pulse is that Metronidazole or Tinidazole are the killer antibiotics (called bactericides) and when Cpn dies it releases toxins into your blood that your body has to process. This pulsing allows your body to recover and makes the treatment more bearable. Too much bacterial kill at one time is overwhelming to the body.  Dr Wheldon regularly revises his protocol and it is worth visiting his website for the latest information. Sriram ProtocolRifampin 150mg Twice a day Take this on its own for two weeks or as toleratedAdd Azithromycin 250mg Mon, Wed, FridayMetronidazole 400mg or 500mg Three times a day Start taking this a month into the treatment and take it for 15 days on 15 days off for the duration of the treatment.Sodium or Calcium Pyruvate 4 to 6g about an hour before antibiotics (twice a day) Start this 8 weeks into the treatment.Rifampin is a very effective killer of RBs (Reticulating Bodies) and therefore it may take a while to feel comfortable taking it. It may take longer than the two weeks suggested in the chart. It is also worth noting that Rifampin can affect the efficacy of other drugs you may be taking such as Thyroxine for example. It may also cause your liver enzymes to become elevated and for that reason you should be closely monitored by a doctor.In this protocol Metronidazole pulses are 15 days long.  This may well be very difficult to sustain and in that case patients have been advised to reduce the pulse to 7 days in 21.Stratton ProtocolThe Stratton protocol starts off in the same way as the Wheldon Protocol. However the aim is to build up to a point where you are taking all three antibiotics (ABXi) continuously. Once you have achieved that you add:Rifampin 150mg Twice a day Build up as tolerated  INH 300mg Once a day Pulsed with metronidazole, or taken daily. 

  • CAP(TiniOnly): 06/07-02/09 for CFS
  • MethylationProtocolSupplements: Started08/08
  • Intermtnt CAP: 02/09-02/10
  • Full MethylProtocol & LDN 02/09
  • Off CAP: 02/10, cont LDN & MethlyProtocol support

Good work, Louise.  I must admit to never looking at that page, but when I did, I must admit that it had become a total mess.......................SarahA Journey through Light and Shadow

Completed Stratton/Wheldon regime for aggressive secondary progressive MS in June 2007, after four years, three of which intermittent.   Still improving bit by bit and no relapses since finishing treatment.

It looks like columns have become 'stacked'.  I doubt it's a dfficult fix, but I can't access the template.  Maybe Red, or Kent, can retrieve it.As it is, it's understandable, especially if you print it out, but it's not what I would call simple for brain-fogged readers.

The difference between what we do and what we are capable of doing would suffice to solve most of the world’s problems. Mohandas Gandhi

Yes Mac, it is pretty evident that the columns have been extracted with the last website update.  I talked to the man and that is currently how it stands and many misreads of dosage and medication frequency can be a confusion caused by it.   Anyway for the time being my rewrite (or should I say sorting out because I changed very few words) just brought the specifics of substance and dosage together as they had been in the chart format that Michele so graciously prepared, but it is now in paragraph form. I am not sure what you mean by AS is, it is understandable.  Does that mean what I have have sorted out from the original page is now understandable or does it mean the original page did not need sorting out?   Funny how printed communication can run a muck.No matter really, none of this is simple for the brain-fogged readers but this forum topic addition to the archives is an improvement to that which is muddled on the website page in question.      Louise  April 2012

  • CAP(TiniOnly): 06/07-02/09 for CFS
  • MethylationProtocolSupplements: Started08/08
  • Intermtnt CAP: 02/09-02/10
  • Full MethylProtocol & LDN 02/09
  • Off CAP: 02/10, cont LDN & MethlyProtocol support

Thanks Sarah,  I know you saw other pages that had become disturbed with the upgrade.  If you would send the links to me via pmessage I will take a look at them over time and do the same as I have for this one.  Louise

  • CAP(TiniOnly): 06/07-02/09 for CFS
  • MethylationProtocolSupplements: Started08/08
  • Intermtnt CAP: 02/09-02/10
  • Full MethylProtocol & LDN 02/09
  • Off CAP: 02/10, cont LDN & MethlyProtocol support