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Hi Linda,Disappointed no- one answered your query as i was interested in the answer too, being an Asthma sufferer!Excerpt from the handbook might help...The NAC Test One indirect indicator of chronic infection with this organism is the N-acetyl cysteine test. This relies on the ability of NAC to rupture the extracellular Elementary Body by opening up surface disulphide bonds in the organism’s geodesic coat, as described above. The EB opens and perishes. The release of naked bacterial components causes local inflammatory symptoms. Because EBs are more numerous in primary respiratory infections, the acellular load of EBs is likely to be highest around respiratory structures. In a positive NAC test the daily administration of 2.4 G of NAC will cause, after a few days, sinusitis-like symptoms, with watery mucous; also a cough productive of a clear, moderately viscous sputum. Systemic symptoms — 'NAC flu' — may also occur. If symptoms are severe, the dose of NAC may be cut down to 600mg and slowly built up as may be tolerated. Symptoms wane, sometimes quickly, after a few days if the chlamydial load is small; if the load is large they may continue for a month or more as the EBs are destroyed and their remains removed by the immune system. As far as I am aware, NAC is unlikely to produce die-off reactions with any other genus. Ciao!n

We re pretty strong here, and you are one of us.  I take 2400  a day and have for years.  I seem to remember that I DID have "flu-like" reactions, but here I am still taking it.  My vote is to try it.  Maybe we will all learn something.  I think you will notice the beginning reactions within hours, but take it for at least a week to be certain.Rica

Thanks for the responses. Supaguy, I'm trying the NAC test as I'm still trying to find a GP who will prescibe the antibiotics for me and I'm hoping as the blood tests came back negative this might sway him. I'm not keen to just buy them online as customs can be pretty strict here (Australia) and I'm concerned as to what might happen if my parcel gets opened. They say they open 1 in 3 packages and I can't afford fines.I started taking NAC yesterday and so far I'm a bit more wheezy than normal but no other symptoms. Will see what happens...Thanks for the support

I have extreme 24 hour a day asthma when not on antibiotics. Nac never gave me a bad reaction but 1 years of combined ab nearly eliminated.my asthma fully. In my case nac did nothing to indicate infection,,

My asthma is gone... antibiotics seem to have reduced it to very minimal levels... If I have exposure to perfumes I can feel it though... but as I avoid them i have no asthma... which is much better than when i could not breath if i missed 1 inhaler dose for an hour and could not breath....I hope it stays away when i finish the antibiotics!