27 Apr 2018
Author
supaguy
Title

I''m going to be trying up to 350 mg capsules of biotin

Body

I had made up 50 size 1 capsules of biotin. They weighed out to about 230 mg. I say about, because each capsule varied quite a bit. Some might not even have weighed as much as 200 mg whilst others might have been more than 250 mg. It was all a matter of how compressed or how full the capsules were.A few weeks ago, I purchased a size 0 capsule filling capping gadget. A few hours ago, I filled another 50 capsules with pure biotin. This time they are size 0 caps rather than size 1. After filling, I weighed as few of them. They are all well over 300 mg.

Comments

MacKintosh

31 Jan 2016 12:08 am

LOL!!!!

The difference between what we do and what we are capable of doing would suffice to solve most of the world’s problems. Mohandas Gandhi

jam

31 Jan 2016 01:07 am

SG, I take 75 mg, x 4 a day -   just built up.  I just needed to get on to it!  Mine are from a guy who has done really well - once again, RRMS, but  he gained better balance, etc.  Has a lot of B supplements.Jam    ☺

Tommi C

31 Jan 2016 01:48 am

Supaguy,Rick started right off at 300mg - and has had no issues.  I recall there is no known toxic level for that stuff.  It is in things like brocolli.  My recollection is that the phase II trial was testing as much as 600mg a day.https://en.wikipedia.org/wiki/Biotin#ToxicityThat's part of this article:https://en.wikipedia.org/wiki/Biotin#ToxicityBest & Highest Regards,Tom C

Proud Parent of Rick - R started CAP in Nov. 13. Small measurable improvements as of 7/14, more by 10/14.  Holding Steady in early 2017.  "I will leave no stone unturned, no theory unexamined, to help my son." Tommi

Daka

31 Jan 2016 07:49 pm

I've been "absent" for a couple of mts, started capsule # 4 on Jan 24 approximately 400mg no issues. 300mg since August '15. Still no significant changes... yet. Any comments?

Tommi C

31 Jan 2016 10:31 pm

Hi Daka,That capsule size seems unlikely to hold 300 milligrams, though it's more than enough for 300 micrograms.  Rick uses size 0 or 00 - and they are 3/4ths full or thereabouts with 300 milligrams.There has been some confusion about micrograms vs. milligrams - a couple of times in this forum, and what doses were actually being tested in clinical trials in France (200mg to 600 mg - milligrams).So - you may want to check the actual amount you are putting in the capsules.The other thing is - while some 91% or more folks in the phase II clinical trial were said to benefit from being treated, there is a lag time between starting the treatment and seeing results that varied from 2 to 8 or 9 months.  Plus, some of the results were faily subtle - measurments of nerve conduction speed improvement for example being one.  Disability measurements being another - and one that was not seen as frequently during the length of the trial. If this stuff does help someone also on a CAP protocol, I speculate that the effects may be more lasting if they discontinue the trial vs. those who are not on a CAP protocol.This article might provide some insight:http://www.capsugel.com/media/library/answers-to-10-common-questions-ab… are other similar articles - search for "capsule size and capacity."We bought a fairly sensitive scale - with a resolution down to 10 milligrams if I recall correctly.  That's more than likely enough resolution when the range is 100 milligrams to 600 millgrams.  Not enough for 300 micrograms probably.Best & Highest Regards,Tom C

Proud Parent of Rick - R started CAP in Nov. 13. Small measurable improvements as of 7/14, more by 10/14.  Holding Steady in early 2017.  "I will leave no stone unturned, no theory unexamined, to help my son." Tommi

Daka

1 Feb 2016 02:41 pm

Correct Tom, I like your approach as a highly detail person ( like my self):-), each capsule holds approximately 95-100mg depends on how dense powder has been packed.I choose #4 (~100mg) as a referent size/ amount, easier to manipulate (I thought) and/or when decide to increase the biotin amount... Simply add/pop one more capsule. :-)))I would also like to thank Sarah who started/brought this info and everybody else decided to go to this journey...I hope I'm clear?Very Best Regards,

30 Jan 2016
supaguy