Submitted by Michèle on Mon, 2006-08-28 18:49

Antifungals and probiotics Caution: most of the information collected here originates from manufacturers so please consider your options carefully.   Some comments have come from users of these products, but as we know from our experiences with other medication each of us is different and may react differently to these products too.   Name Dosage Mode of Action Comments Acidophilus and other “good” intestinal flora See recommended dosage by manufacturer. Replaces intestinal flora killed by antibiotics and/or imbalanced by Cpn, Candida, etc. Helps prevents C. Difficile infection from antibiotics. Best is a multi-flora formulation. Enteric coated may help better survive stomach acids. Essential when using CAP’s Calendula oil Apply locally  Antifungal Cheap Candex 2 x 2 daily Fibre digesting enzymes eat candida cell walls Not cheap. Does not need refrigeration Caprylic acid Up to 1500mg daily Based on Coconut oil antifungal antiviral Can irritate sensitive GI mucous membranes Curcumin/ Turmeric 500 to 1500mg daily Anti-inflammatory antifungal Cheap Diflucan/ fluconazole 200mg 2-3 times per week by prescription  Antifungal Uses p450 liver enzymes for metabolism, so caution if liver is affected. Fungizone Administrated intravenously by prescription Antifungal interferes with candida cell walls For systemic life threatening infections. Grapefruit seed extract Between meals 125mg x 2 daily Antifungal Disrupts fungal cell membranes Reasonably priced Kolorex 1 cap x2 daily Herbal antifungal Not cheap Lamisil/ terbinafine 250mg daily or as directed prescription only Antifungal works by interfering with fungal cell walls Can affect liver function N-acetyl cysteine 2x600mg Possible Antifungal action N-acetyl cysteine may discourage colonization with Candida albicans Nystatin As prescribed by doctor Antymycotic, antifungal affecting fungal cell walls Allow lozenges to dissolve in the mouth. Olive leaf extract 1-2 caps twice a day Anti-viral, anti-candidal, antibacterial. Stimulates NK cell production, so is immune boosting Oregano oil  Also in capsules As directed 450mg x2 Antifungal, anticandidal, antiviral Can be used as preventative or treatment of intestinal candida.   Cheap Pangamin Bifi Plus 4tbl 2-3x daily bifidobacteria and lactobacilli, saccharomyces cerevisiae Cheap, available in Czech Republic or internet. Probiotic Defense." Now Foods 1x3 daily Probiotic Homeostatic Soil Organisms Not cheap Saccharomyces boulardii 150mg taken between meals Probiotic yeast survives antibiotics Do not take with Nystatin, Diflucan, sporonox or other antifungals. Not expensive Tanalbit 30 Mins before meals 2 caps 3x per day Tannin based antimycotic, attaches to fungal cells preventing colonisation Not cheap, casein based Threelac 1 or 2 sachets daily Probiotic, microencapsulated Very expensive Undecyclenic acid   450 – 750mg daily in 3 doses Antifungal 6 times more effective than caprylic acid Can irritate sensitive GI mucous membranes   Although the terms antifungals and probiotics are often used synonymously their actions are slightly different.   Antifungals work by using the differences between human and fungal cells to kill off the fungal organism without harming our own body cell.   However some antifungals can irritate the gut especially if it is particularly sensitive.  Probiotics work by supplying us with the necessary good bacteria or yeasts our GI tracts need for healthy operation.  Lactic acid bacteria (LAB) are the most common organisms used. Homeostatic Soil Organisms HSOs are probiotics comprising organisms that destroy fungus.   HSOs were originally found in soil and subsequently cultivated.


 Excellent, MichelleThis probably answers unasked  questions that brain-fogged people did not even know they had.  This is such an important part of the complete regimen since the abx will kill off many of the "good gut bugs" that are of great importance to all but especially those of us who labor just to keep a semblance of a real life.   Fortunately, it is very easy for us to just "pop another pill" of acidophilus a couple of hours AFTER our abx to ensure a numerous number - or eat yogurt  Actually, I just take 1 with my AM supps and another with PM.. Rica        EDSS 6.7 at beginning - now 2 Ignorance is voluntary bad luck.  Lauritz S.   A true Viking If you come to a fork in the road, take it. Yogi Berra

3/9 Symptoms returning. Began 5 abx protocol 5/9 Rifampin 600, Amox 1000, Doxy 200, MWF Azith 250, flagyl 1000 daily. Began Sept 04 PPMS EDSS 6.7 Now good days EDSS 1 Mind, like parachute, work only when open. Charlie Chan  In for the duration.&am

Michele,  Good work!  Rica's right...this is a vitally helpful addition to the site.  Never heard of some of those things which only demonstrates that the more you know, the more you can imagine how much you still don't know.  This will be a good reference for current and future decision-making.  Thanks,  Joyce~~~MS caregiver and advocate - Dallas

Joyce~caregiver-advocate in Dallas for Steve J (SPMS).  CAP since August 06, Cpn, Mpn, B. burgdorferi, systemic candidiasis, EBV, CMV & other herpes family viral infections, elevated heavy metals, gluten+casein sensitivity. 

Michele, this is great -- your career pays off for the rest of us. I've heard education described as "putting the cookies (biscuits?) on the lowest shelf;" this is a good example!Thank you! RonOn Stratton protocol for CFS starting 01/06 (NE Ohio, USA).

RonOn CAP for CFS starting 01/06 (NE Ohio, USA)Began rifampin trial 1/14/09Currently: on intermittent