26 Dec 2008 12:13 am
27 Apr 2018
Title
Bacterial Genomics Reveals MS Trigger
Body
Infection with a common bacteria could be the switch that turns on the autoimmune response in multiple sclerosis (MS) according to the findings of Wayne State University PhD graduate, Derek Lenz, now of the Scripps Research Institute in La Jolla, Calif. He described the work he carried out as part of Robert Swanborg’s team at Wayne State University School of Medicine. He said studies in rats show that an antigen found in the bacteria Chlamydia pneumoniae mimics part of a myelin protein in the animal’s central nervous system.
Comments
26 Dec 2008 03:31 am
Well of course we knew this
Well of course we knew this here, but isn't it great to have ones beliefs validated, yet again.
Michèle (UK) GFA: Wheldon CAP 1st May 2006. Daily Doxy, Azi MWF, metro pulse.
26 Dec 2008 09:01 am
Jeanneroz, could you cut
Jeanneroz, could you cut and past the full link out in view then add a space to it and it may work for me. I cannot access the article throught the link mechanism that you provided. Thanks for sharing. Louise
- CAP(TiniOnly): 06/07-02/09 for CFS
- MethylationProtocolSupplements: Started08/08
- Intermtnt CAP: 02/09-02/10
- Full MethylProtocol & LDN 02/09
- Off CAP: 02/10, cont LDN & MethlyProtocol support
26 Dec 2008 10:04 am
A doctor who does his
A doctor who does his homework, good deal. More doctors should be a little more curious about their profession and read up on stuff like this. We the patient shouldnt have to be the initiater.
Fibro, CFS, Myco, CPN, Stratton protocol, Zithro 500mg M/W/F/S, Doxy 100mg 2x day, NAC 1200mg 2x day, Flagyl and INH 2 week pulses 400 mg 3x day, Rifampin, 300mg 2x day, Still cant shake it but improving.
26 Dec 2008 12:15 pm
Yet, we are the initiators
Yet, we are the initiators and have been for a very long time.Thank goodness, we are not alone and have the brilliant questioning that makes this site so unique.
Educating neuros is a good idea if one can bear hearing the negativity aimed at all of us.
Everyone here, man or woman - YOU GO!!!!!!
Happy 2009. I am with all of you, in spirit, hopes and desires.
Loulou
diagnosed MS Jan.2000 , chronic neurological lyme disease Nov.2002.doxy 100 mg. 1BID. roxy.150 mg.? BID,adding rifampin soon, pulsed tini. every 3 weeks, as of oct.17/08, rifampin,naltrexone (LDN),NAC, nystatin, major wheldon supplemrnts daily,
26 Dec 2008 06:02 pm
Season's greetings
Season's greetings everyone, but has anyone noticed that this link from Wayne State University is six years old?.............Sarah
An Itinerary in Light and Shadow
Completed Stratton/Wheldon regime for aggressive secondary progressive MS in June 2007, after four years, three of which intermittent. Still improving bit by bit and no relapses since finishing treatment.
I didn't really think it
I didn't really think it mattered... but don't you find it interesting that 6 YEARS AGO they made the possible connection??
JeanneRoz ~ DX'd w/ CPN 4/2007; 6/07 -"officially" dx'd w/CFIDS/FM; also: HHV6, EBV, IBS-C, 100 Doxy:BID; 500 mg Biaxin BID; Tindamax Pulses, B12 shots, ERFA Dessicated Thyroid,Cortef, Iodoral 25 mg, Vit D-6,000 uni
26 Dec 2008 08:18 pm
Wayne State has been doing
Wayne State has been doing work of this sort for many years.Dr. Lida Mattman , recently deceased, virologist, etc. penned the medical book Stealth Pathogens in the 80s out of Wayne State. Originally professor emeritus from Yale - a brilliant woman and ahead of her time.
So we all should pay attention.
Loulou
diagnosed MS Jan.2000 , chronic neurological lyme disease Nov.2002.doxy 100 mg. 1BID. roxy.150 mg.? BID,adding rifampin soon, pulsed tini. every 3 weeks, as of oct.17/08, rifampin,naltrexone (LDN),NAC, nystatin, major wheldon supplemrnts daily,
26 Dec 2008 11:17 pm
Actually, as I read it,
Actually, as I read it, cpn is here considered a trigger for the AUTO-IMMUNE disease of ms. That's a possibility that we have not ruled out but, as I understand it, we do not generally consider MS an auto-immune disease. Am I wrong?
PPMS-misdiagnosed 2001-diagnosed 2006. Probably caught cpn in birth canal but it didn't pass BBB until my 40s. Minocycline 7 mos.- resulting bronchitis 5 months.Go to private m.d. out-of-plan. Wheldon CAP 3/2/07 Stopped 12/12; resumed 12/13
27 Dec 2008 09:34 am
Autoimmune or
Autoimmune or not?????????????That is the pervasive question..................Some neuros say yes autoimmune, others say no...
Dr. Wheldons protocol gives us some hope..The rest are merely names - I keep going.What else is there??
LOULOU
diagnosed MS Jan.2000 , chronic neurological lyme disease Nov.2002.doxy 100 mg. 1BID. roxy.150 mg.? BID,adding rifampin soon, pulsed tini. every 3 weeks, as of oct.17/08, rifampin,naltrexone (LDN),NAC, nystatin, major wheldon supplemrnts daily,
27 Dec 2008 07:18 pm
Sorry, everyone, but I
Sorry, everyone, but I didn't think anyone had noticed the date. This is old news and DW was corresponding with Hudson years ago. I thought it was sad that things had changed so little since then................Sarah
An Itinerary in Light and Shadow
Completed Stratton/Wheldon regime for aggressive secondary progressive MS in June 2007, after four years, three of which intermittent. Still improving bit by bit and no relapses since finishing treatment.
27 Dec 2008 07:45 pm
It is definitely sad. Thank
It is definitely sad. Thank you DW .
Things in medicine are profoundly slow.Sarah, I'm sure you know more about the inner circles of the med. system than most?
This, so to speak, hierarchy makes us so aware that pharmaceutical companies appear to unfortunately govern medicine and the "practice" of it.eg. no cause, no cure, bacterial, viral, and the list goes on and on.....
Forget the politics as much as possible. Do what you can . Exercise, go outside (weather permitting), stay on CPN.....................
Loulou
I'm starting to sound political. Must be the times we're living in.
Happy 2009
diagnosed MS Jan.2000 , chronic neurological lyme disease Nov.2002.doxy 100 mg. 1BID. roxy.150 mg.? BID,adding rifampin soon, pulsed tini. every 3 weeks, as of oct.17/08, rifampin,naltrexone (LDN),NAC, nystatin, major wheldon supplemrnts daily,
loulou - "Stay on
loulou - "Stay on cpn"???????? You are hereby banished from the punchbowl. Cpn=bad. ABX=good. 
The difference between what we do and what we are capable of doing would suffice to solve most of the world’s problems. Mohandas Gandhi
27 Dec 2008 08:50 pm
It is possible it is
It is possible it is autoimmune and directly attacks tissue, HSP 60 maybe, and very likely genetic and environmental. That is maybe why it has taken so long to tie everything together, many variables.
The body is very complex, it is very hard to experiment with people much less track them. Medicine is very political. All things to slow finding the cure. Many very fine doctors now are on the germs trail, it will get a lot harder for it to do damage as before.
Cpn, Mycoplasma, Chronic EBV, M.S.(MRI, Spinal Tap-greater than 5 oligoclonal bands and VEP), PANDAS(OCD). Wheldon CAP (started 12/08), Azithromycin/Clarithromycin(12/09), Lithium, Lamictal, NAC(2.4g/day), D3(15,000IU/day)
28 Dec 2008 07:58 pm
Whoops! Confused for a
Whoops! Confused for a change.....................not cpn YES cap, YES antis.
Thanks Mac for pointing that out- I missed it.
Loulou
diagnosed MS Jan.2000 , chronic neurological lyme disease Nov.2002.doxy 100 mg. 1BID. roxy.150 mg.? BID,adding rifampin soon, pulsed tini. every 3 weeks, as of oct.17/08, rifampin,naltrexone (LDN),NAC, nystatin, major wheldon supplemrnts daily,
28 Dec 2008 08:09 pm
If Dr. Lida Mattman wrote
If Dr. Lida Mattman wrote the medical book "Stealth Pathogens" in the 80's, and was a Nobel Prize candidate because of it, then why in the world are so many having so much trouble finding doctors who will go along with this protocol, and why is there such a battle within the medical community? I honestly and truly don't understand.
Kelly
Diagnosed FMS Feb '07. 2x/day: 600 mg NAC, 100 mg Doxy, 500 mg Amoxicillin, 2000 iu Vit. D. 450 mg Valcyte. 250 mg Azi M/W/F. 500 mg 375 mg Flagyl pulses every 3-4 weeks. Started CAP June '07.
Good point Kelly, it really
Good point Kelly, it really is baffling.
speedbird
29 Dec 2008 08:42 am
I wish I knew a solid
I wish I knew a solid unbiased answer to your valid questions.
Get involved with ILADS. mORE INFO THat ,as me, will make you more aware, however, add to your confusion. Hoping this baffling info will stop, once and for all BUT I bet it doesn't!!
Happy 2009
Loulou
ps Let it suffice to inform you that Dr. Mattman was hidden, literally, for her beliefs, almost thrown in jail, etc.etc. I stayed with her close to the end of her proud,informative life. I learned a lot from her.
diagnosed MS Jan.2000 , chronic neurological lyme disease Nov.2002.doxy 100 mg. 1BID. roxy.150 mg.? BID,adding rifampin soon, pulsed tini. every 3 weeks, as of oct.17/08, rifampin,naltrexone (LDN),NAC, nystatin, major wheldon supplemrnts daily,
Wow, LouLou - where was
Wow, LouLou - where was Erin Brockovich during all of this?! Dr. Mattman's story sounds fascinating - it would be great to see a book written about her life! She really was the pioneer, wasn't she? So sad that she was also a pioneer for those persecuted for daring to have evidence that contradicts those who hold the power.
Kelly
Diagnosed FMS Feb '07. 2x/day: 600 mg NAC, 100 mg Doxy, 500 mg Amoxicillin, 2000 iu Vit. D. 450 mg Valcyte. 250 mg Azi M/W/F. 500 mg 375 mg Flagyl pulses every 3-4 weeks. Started CAP June '07.
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25 Dec 2008
You GO, Derek Lenz! Thanks
You GO, Derek Lenz! Thanks for finding this Jeanneroz. I am SO going to enjoy re-educating that young neuro I fired three years ago!
The difference between what we do and what we are capable of doing would suffice to solve most of the world’s problems. Mohandas Gandhi