Antifungals and probiotics Caution: most of the information collected here originates from manufacturers so please consider your options carefully. Some comments have come from users of these products, but as we know from our experiences with other medication each of us is different and may react differently to these products too. Name Dosage Mode of Action Comments Acidophilus and other “good” intestinal flora See recommended dosage by manufacturer. Replaces intestinal flora killed by antibiotics and/or imbalanced by Cpn, Candida, etc. Helps prevents C. Difficile infection from antibiotics. Best is a multi-flora formulation. Enteric coated may help better survive stomach acids. Essential when using CAP’s Calendula oil Apply locally Antifungal Cheap Candex 2 x 2 daily Fibre digesting enzymes eat candida cell walls Not cheap. Does not need refrigeration Caprylic acid Up to 1500mg daily Based on Coconut oil antifungal antiviral Can irritate sensitive GI mucous membranes Curcumin/ Turmeric 500 to 1500mg daily Anti-inflammatory antifungal Cheap Diflucan/ fluconazole 200mg 2-3 times per week by prescription Antifungal Uses p450 liver enzymes for metabolism, so caution if liver is affected. Fungizone Administrated intravenously by prescription Antifungal interferes with candida cell walls For systemic life threatening infections. Grapefruit seed extract Between meals 125mg x 2 daily Antifungal Disrupts fungal cell membranes Reasonably priced Kolorex 1 cap x2 daily Herbal antifungal Not cheap Lamisil/ terbinafine 250mg daily or as directed prescription only Antifungal works by interfering with fungal cell walls Can affect liver function N-acetyl cysteine 2x600mg Possible Antifungal action N-acetyl cysteine may discourage colonization with Candida albicans Nystatin As prescribed by doctor Antymycotic, antifungal affecting fungal cell walls Allow lozenges to dissolve in the mouth. Olive leaf extract 1-2 caps twice a day Anti-viral, anti-candidal, antibacterial. Stimulates NK cell production, so is immune boosting Oregano oil Also in capsules As directed 450mg x2 Antifungal, anticandidal, antiviral Can be used as preventative or treatment of intestinal candida. Cheap Pangamin Bifi Plus 4tbl 2-3x daily bifidobacteria and lactobacilli, saccharomyces cerevisiae Cheap, available in Czech Republic or internet. Probiotic Defense." Now Foods 1x3 daily Probiotic Homeostatic Soil Organisms Not cheap Saccharomyces boulardii 150mg taken between meals Probiotic yeast survives antibiotics Do not take with Nystatin, Diflucan, sporonox or other antifungals. Not expensive Tanalbit 30 Mins before meals 2 caps 3x per day Tannin based antimycotic, attaches to fungal cells preventing colonisation Not cheap, casein based Threelac 1 or 2 sachets daily Probiotic, microencapsulated Very expensive Undecyclenic acid 450 – 750mg daily in 3 doses Antifungal 6 times more effective than caprylic acid Can irritate sensitive GI mucous membranes Although the terms antifungals and probiotics are often used synonymously their actions are slightly different. Antifungals work by using the differences between human and fungal cells to kill off the fungal organism without harming our own body cell. However some antifungals can irritate the gut especially if it is particularly sensitive. Probiotics work by supplying us with the necessary good bacteria or yeasts our GI tracts need for healthy operation. Lactic acid bacteria (LAB) are the most common organisms used. Homeostatic Soil Organisms HSOs are probiotics comprising organisms that destroy fungus. HSOs were originally found in soil and subsequently cultivated.