27 Apr 2018

fungal sinusitis and related issues


Daisy and Michele have brought up a subject of general interest which I thought deserved its own thread.


That makes sense to me.   Cpn infects my sinus and aggravates fungi... So unless you eliminate either or both you are going to have a chronic infection.

Michele (UK) GFA: Wheldon CAP1st May 2006 . Daily Doxy, Azi MWF, Flagyl at 400mg for 7 days prior to 5 day pulses at 1200mg three weeks cycle. Spokesperson for Ella, RRMS Wheldon CAP 16th March 2006

Michèle (UK) GFA: Wheldon CAP 1st May 2006. Daily Doxy, Azi MWF, metro pulse.


Thanks for the further explanation, DW. This makes perfect sense to me too, and it seems to explain well my sinus related issues that also seemed to clear up with treatment.

Also, I've battled frequent recurrent tinea infections for over 20 years, but haven't had any recurrence since very early on in CAP. And while I didn't keep very good notes on my mostly scalp related seb derm (and from what I understand, most would generally consider malessizia yeasts to be implicated in this condition), as I remember, it seemed to start clearing up in early CAP, and disappeared completely when I added in the Vit D3. I haven't had any real signs of it in months.

One odd sinus-related issue I have noticed while now on Vit D3 + NAC + Fir sauna is that when I hit it too hard, by taking a larger dose of Vit D3 or staying in the sauna too long (or turning up the heat setting too high), I get a really awful night's sleep with lots of night sweats and tossing and turning combined with a day or so (if I cut back) of stuffy sinuses and popping ears, generaly lung congestion etc. I got this same result yesterday / last night by adding in a 2 mile run in the heat to my normal regimine.

Again, now for me this is very apparent because normally my sinuses / ears and lungs are completely clear at this point. Could some of this congestion / stuffiness be related to an allergic type response to the endotoxins released in a Cpn die-off as well?


On Combined Antibiotic Protocol for Cpn in Rosacea 01/06 - 07/07, On Vit D3 + NAC since 07/07 and daily FIR Sauna since 08/07

Treatment for Rosacea

  • CAP:  01/06-07/07
  • High-Dose Vit D3, NAC:  07/07-11/08
  • Intermtnt CAP, HDose Vit D3:  11/08-01/09
  • HDose Vit D3, Mg, Zn: 01/09-

Thanks for the insight...

The past few weeks my sinuses have been more active & as well, I have been having problems with my voice box, crackly & have not been able to sing my usual range.  Having to do lots of throat clearing.  In my 20's I had laringitis a few times for a week at a time?  Yes, it was very quiet!!Image removed.

My husband has had a recurring cough for many years, as soon as he gets run down it takes hold & quickly moves into his chest.  He doesn't take good care of himself which totally ticks me off as I have to do overkill on the complete opposite of that spectrum!  MEN!!!

Anyway, he is going to be on the NAC soon as his cough settles a bit again.  I will take that as a window of opportunity to start & hope my hubby takes his vitamins!



CFIDS/ME 25yrs, FMS, IBS, EBV, Cpn, (insomnia - melatonin, GABA, tarazadone, temazepam, novocyclopine, allergy formula, 2 gm tryptophan), Natural HRT peri-M, NAC 2.5 gm, 6-07 Doxy 200 mg day pm, Azith 375 mg M/W/Fday, 8-21-07 1st pulse 1 X 250 mg Metro

CFIDS/ME, FMS, MCS, IBS, EBV, CMV, Cpn, H1, chronic insomnia, Chronic Lyme, HME, Babesia, Natural HRT-menopause, NAC 2.4 gm,Full CAP 6-2-07, all supplements+Iodorol, Inositol-depression, ultra Chitosan, L lysine Pulse#27 04-19-10 1gm Flagyl/day-5 days<

 Since starting CAP about 10 weeks ago, I have noticed an increase in smell. Before hand (since I was a teenager), I have poor olfactory senses.  I never knew how bad  Lantana's (garden plant) smelt until now.  

Mphs, TN. adrenal fatigue and CFS. 6/26/07- CPN Titer 1:256 (normal 1:16); 6/27/07-started NAC; 7/2/07-started doxycycline 100 mg twice daily; 7/19/07 started Biaxin 250mg per day. 9/7/07-stopped Biaxin and started on Azithromycin 500 mg every other

Mphs, TN. CFS, hypoT (Hashi), adrenal fatigue, hormonal inbalance. right arm neuropathy-getting better. cpn, myco, EBV, CMV, HHV-6. Cap began in 6/07. NAC 2400mg, mino 100mg bid, biaxin 500mg bid. cytomel, flagyl bid continuously.

Nice, Sharon! I call them "whispers" and you are listening. And, next spring, you can see the lantana from a distance and go straight to the gardenias and roses - what a treat!


Rica PPMS EDSS 6.7 at beginning - now 2. Began CAP Sept, 2004 with Rifampin 150 mg 2xd, Doxy 100 mg 2xd, added regular pulses Jan 2005. Jan 2006 switched to Doxy, Azith, cont. flagyl total 44 pulses NC USA

3/9 Symptoms returning. Began 5 abx protocol 5/9 Rifampin 600, Amox 1000, Doxy 200, MWF Azith 250, flagyl 1000 daily. Began Sept 04 PPMS EDSS 6.7 Now good days EDSS 1 Mind, like parachute, work only when open. Charlie Chan  In for the duration.&am

David -

Excellent reasoning as usual!  CPN or mold to me is a chicken or egg situation?  Or I guess to be more precise, is CPN predominantly the "cause" or the "catalyst" of all the various ills we discuss on this site?  

Here and Here are two quick bits of information on the original Mayo study and patent on fungal and bacterial sinusitis. 

I especially love this quote  - "However, patients diagnosed with Chronic RhinoSinusitis (CRS) have an immunologic response to the fungi causing activated white blood cells (eosinophils) to enter their mucus. The activated eosinophils release a major basic protein -- a toxic protein -- into the mucus, which attacks and kills the fungi but damages the nose and sinus membranes. The major basic protein also injures the epithelium, which allows bacteria to infect the tissues." 

So in theory if you are already CPN infected, your infected immune system will travel to the site of the fungal infection and set up permanent house keeping...  Otherwise, you in theory are a sitting duck with a fungal infection for picking up all sorts of other bacterium which are also implicated in chronic sinusitis.

The plot thickens... or should I say the mucus thickens...

htmDaisy-Caregiver- Balo's Concentric Sclerosis. Began CAP 5/10/07. Doxy 200 mg, Mino 100 BID 9/1/07, AZI 250mg QD 9/10/07, NAC 1800 mg QD, HD Flagyl Pulses, Novantrone, Prednisone & daily lb of supplements.

Daisy - Husband on CAP 5/07.  Husband died from Acute Myelogenous Leukemia Secondary to the Infusion of Novantrone.  Ie - the treatment with the conventional MS drugs killed him. Daisy on her own CAP 11/2012. 

 Oh Daisy, I'm afraid my predilection for horrid puns may be infectious given your "thickening" comment. Or perhaps the disease has already been well rooted in you. I've not found it curable. In fact it's quite clear that flagyl, or any attempts at treatment make it worse.

David- You've given us a very useful reference point here, which I think will help many with diverse diseases but common overlapping co-conditions. In my recent attempts to collate last years survey, the most common diagnosis along with the main complaint has been sinusitus. Those of us with "immune deficiency" such as CFS often assume this is just one more burden brought about by our central condition, that we don't fight these things off, whereas others may never connect their main diagnosed disease with their sinus complaints. Why should MS and sinusitis have anything in common? Even more so for something like hypertension. At least on the surface.

CAP for Chlamydia pneumonia since 11/04. 25yrs CFS & FMS- Currently: 300mg INH, 200 Doxycycline, 500mg MWF Azithromycin, 1000mg Tini daily (Taking a break from continuous protocol)

Here is an interesting series of abstracts that trace the recent history of research into CRS.   Reading about all the research being done you wonder how these are being funded.   Is there a lot of money to be made from curing sinusitis?  

The second abstract postulates that CRS is the result of a combination of pathogens, which may vary from region to region and from patient to patient.   Fungus is one of them, but they think not the only one. 

Michele (UK) GFA: Wheldon CAP1st May 2006 . Daily Doxy, Azi MWF, Flagyl at 400mg for 7 days prior to 5 day pulses at 1200mg three weeks cycle. Spokesperson for Ella, RRMS Wheldon CAP 16th March 2006

Michèle (UK) GFA: Wheldon CAP 1st May 2006. Daily Doxy, Azi MWF, metro pulse.