Doxycycline vs rifampicin

Can anyone enlighten me about the differences and advantages (or not) of using rifampicin instead of doxycycline, please?

Basically, if you are doing it yourself, steer clear of Rifampicin, unless  you want liver damage.  I took it for six months back when David was unsure aout allowing anyone to take abx for longer than six months, so he changed my doxycycline for rifampicin.  It made my walking worse for a while, plus if you forget to flush the loo, the colour will make your wife very worried...........Sarah

A Journey through Light and Shadow

Completed Stratton/Wheldon regime for aggressive secondary progressive MS in June 2007, after four years, three of which intermittent.   Still improving bit by bit and no relapses since finishing treatment.

Hi & thanks for the reply.

I am mulling over whether I want liver damage or not  ....  I'll come back to you on that one (lol).

As for the colour of what one deposits in the loo  ...  my woman's cooking dinner right now  ...  I'll run the possibilities past her as  we're munching our melon, do think?

Nah, ... think I'll stick to the doxy.

Oh, and thanks again.

“Don't believe everything you read on the internet.”

―    Abraham Lincoln

supaguy,  NAC is liver-protective, so rifampin isn't such a scary alternative.  Many people here self-treat, but they are ALSO monitored by their non-prescribing doctors.  In other words, you can still have the tests done and keep tabs on your numbers and liver function and vitamin levels, even though your physician declines to actually prescribe.

The difference between what we do and what we are capable of doing would suffice to solve most of the world’s problems. Mohandas Gandhi

Rifampin was my first abx, followed a week later with Doxy.  I was on it with Avonex for 77 weeks.  My numbers for my liver were so high that my doctor had me stop all abx for one month.  I stopped Avonex also and my numbers were normal after that - for another seven and a half years - and never rose again.  But...it IS a committment.  You must not eat for two hours before and one hour after taking it.    This is very serious thing for me - we are very fortunate to have this opportunity and, I believe, should take the resposibility also seriously.  I also drank lots of water, ate very well, and took all my supps.  I missed very few doses of any abx.

The People's Pharmacy is a program that we hear frequently.  This past Saturday was on Borrellia - and Rifampin is very important in treating that.  I was told by a doctor here that you should treat Borrellia or our protocol may well not be very effective.  I was bitten by many, many ticks as a kid riding through the Indiana forests and probably had something that they gave me.

Rica

3/9 Symptoms returning. Began 5 abx protocol 5/9 Rifampin 600, Amox 1000, Doxy 200, MWF Azith 250, flagyl 1000 daily. Began Sept 04 PPMS EDSS 6.7 Now good days EDSS 1 Mind, like parachute, work only when open. Charlie Chan  In for the duration.&am

It does sometimes make me wonder whether I'll ever be able to get properly well, if I'm not able to use rifampicin at some point, as I may well have co-infections. But no point in worrying about it for the moment.

Neuro symptoms & many health problems from 1989. NAC+all supps(04/11) CAP(05/11)

Boadicea, since doxycycline and roxithromycin, are like rifampicin, both broad based antibiotics. They will treat virtually any bacterial pathogen, so since you are taking them for longer than just the normal five day treatment, there is no reason why you should not recover unless you have something untreatable with antibiotics.

I was given Rifampicin because, in those early days, David was worried about giving any antibiotic for longer than six months.  My major neurological improvements had already been set in place before I started rifampicin, which I never liked.  I feel confident in saying that I didn’t need it to ensure recovery....................Sarah

A Journey through Light and Shadow

Completed Stratton/Wheldon regime for aggressive secondary progressive MS in June 2007, after four years, three of which intermittent.   Still improving bit by bit and no relapses since finishing treatment.

Many thanks, Sarah.  Much appreciated. I've not missed a day of doxy and roxi in over two years! Lots of reaction to abx, and occasional good glimmers, so still hopeful.

Neuro symptoms & many health problems from 1989. NAC+all supps(04/11) CAP(05/11)

I've been on over a week of doxy+tinidazole+rox and don't have any lasting improvements it seems.  I'm switching over to rifampacin soon hopefully

I had a really terrible experience with azithromycin I was on it weekly for 6 weeks and then about 2 months later I couldn't exhale with resistance.  Later my CT confirmed asthma

I can't access my other account.  I am about to switch over from tinidazole+doxy+roxy to rifampacin+INH for a few weeks. 

Can rifampacin damage the liver even when taking NAC?  High AST ALT numbers clearly seem to indicate liver damage

I am having unexplained terrible blurry vision, loss of hearing, hearing humming sounds/tinnitus, inability to speak or understand people.  I'm also having balance problems, problems walking from dizziness.  I didn't have this on flagyl so I doubt it's from tinidazole. 

I'm on an asv ventilator for severe sleep apnea, hypoxia at night.  so maybe I could have a demyelination disease? 

I've read Sam-E could possibly help with myelin or maybe methylation supplements?