Do I need to worry ?

I had borreliosis last winter and treated it with doxycyclin for 5 weeks 100mg / d.

Last year in summer i had ch. trachomatis which i also treated with a tetracyclin, i don't remember which one exactly. Now to confirm I am no longer infected with borrelia I took a blood test, and tested for borrelia:

IgG pos but IgM neg. And for chlamydia, and this shows CPn values:

IgA-AK 45 U/ml

IgG-AK 135 U/ml

IgM-AK 1,1 S/CO

 

Method was an EIA. I have dry coughs sometime, that have been bothering me, so I wondered: Do I have to worry? What treatments are available? From reading some posts in this forum, I know that I'm a really light case, but still any help will be greatly appreciated.

 

Thanks

Many of us have not been tested but there will be a few members who will be able to tell you what these results mean.

The trouble with Cpn is that test don't always show the real problem.   Many of us have used the NAC test as a way to satisfy themselve that they had a Cpn infection.   NAC (N-acetyl cysteine), is a supplement sold in health food shops, that kills Cpn in one of its reproductive stages.   If you have a reaction to taking this supplement (sneezes, flu like symptoms) then you know that you have a Cpn infection that should be treated.

This treatment is long term and can be unpleasant.   It might be an idea for you to read the handbook, to get an overview of what it consists of and you will also learn more about Cpn and how it affects your body.

Michele:  on Wheldon protocol since 1st May 2006 for a variety of long standing ailments including IBS, sinusitis, alopecia, asthma, peripheral neuropathy, also spokesperson for Ella started Wheldon CAP 16th March 2006 for RRMS

Michèle (UK) GFA: Wheldon CAP 1st May 2006. Daily Doxy, Azi MWF, metro pulse.

D W

The laboratory which did the test should provide a comment. We always do, even if it's to say 'I don't know what this means.' 

One EIA test we have used in determining the levels and classes of antibodies against C. pneumoniae is the SeroCP Quant kit test; it is made by Savyon Diagnostics in Israel. It is a very nice test to use. Here is a link to Savyon's page on SeroCP Quant. (Link) From this page you can download a pdf instruction manual; it's worth reading because it gives you the essentials of the various classes of antibody in acute and persistent infections as well as the principle of the test. The results are given in 'Binding Units' which are determined by constructing a graph of the results obtained from calibration sera of known Binding Unit value; the results from test and control sera are measured against this line. Binding Units are not absolute, and the values obtained have to be set against the cutoff. The cutoff is defined as the value below which the results are nonspecific and above which the results are specific. In the case of this test the cutoff is 10 BU/mL. Test sera which have a value below this are negative and above this are positive. You will see that the cutoff is the key to reading the result, and must be given with the result.

We have found this test very useful. Results accord with the clinical picture, and, in positives are usually way above the cutoff, and, in negatives, are usually very low(one criterion of a good test.) Because the organism is intracellular, IgA results in chronic disease may initially be negative; however, they may rise during antibiotic treatment as bacterial antigens are released. Such a rise gives very strong evidence of chronic C. pneumoniae infection. I liked this test.

D W - [Myalgia and hypertension (typically 155/95.) Began (2003) taking doxycycline and macrolide and later adding metronidazole. Improved; normotensive.]

D W - [Myalgia and hypertension (typically 155/95.) Began (2003) taking doxycycline and macrolide and later adding metronidazole. No medication now. Morning BP typically 110/75]

Thanks for the help! I tried to talk to the guys at the lab, but had no luck reaching them yet, but i will try the nac, just to see.

I though another good idea, is to make another test in about half a year and see if the values are increasing.

I heard that approx 50-70% of the population are infected with CPn but like herpes only few actually have problems.

Still, thanks everybody, ir was certainly helpfull

50-70% are seropositive I assume you mean...seropositivity means that the person has been exposed to Cpn at some point, not necessarily that they are currently infected. I dont believe anyone actually knows how many people are infected at any one time, since this would require a large sample of the population and also a means to determine whether they are currently carrying cpn (probably by culturing it-which is notoriously difficult). Just thought I would clarify that...

Image removed.

MBioChem, currently studying medicine, research project on Cpn and atherosclerosis

Dan- You are correct. By age 60, about 60% show antigens for having been exposed to Cpn, not that they show demonstrable current infection.

However, it's worth noting that 25% of "healthy young blood donors" show indicators of viable Cpn, ie are culture positive (discussed here: http://www.cpnhelp.org/?q=recentobservations). How about unhealthy young? Unhealthy middle aged? Etc. 

CAP for Chlamydia pneumonia since 11/04. 25yrs CFS & FMS- Currently: 150mg INH, 300mg Rifampin, 200 Doxycycline, 500mg mwf Azithromycin, plus 500mg Tinidazole 2x/day pulses every two weeks. Whew! That's a lot! about 60% recovery. Ohio,

 

CAP for Cpn 11/04. Dx: 25+yrs CFS & FMS. Currently: 250 aithromycin mwf, doxycycline 100mg BID, restarted Tini pulses; Vit D2000 units, T4 & T3, 6mg Iodoral