Cytochrome P450, Drug Interactions, & Secondary Porphyria
I’ve read a good deal of discussion about these issues since starting on CAP. Perhaps I’ve overlooked something in the archives, but I’ve read some recent sources that have given me new information about this complex topic. Cytochrome P450 (CYP) is an isoenzyme, so called because it is closely related to other variants by homologous genes. They are named by a root (CYP), family (a number), a subfamily (a letter), and then the gene (another number). So, for example, one isoenzyme goes by the name of CYP2D6. CYP isoenzymes in the same family and subfamilies share structural similarities.