These links present this topic best:
*The pdf of Charles Stratton's review of Cpn in Chronic Disease : http://www.cpnhelp.org/pdfs/ChronicDisease.pdf
A detailed review of Cpn in chronic diseases at: http://www.chlamydiae.com/Chlamydophila_pneumoniae_introbk.asp
Crossing the Barriers http://www.cpnhelp.org/?q=node/35
We will have separate pages eventually which discuss specific Cpn in diseases eventually. For now you can find these reference links as starter points.
David Wheldon't site http://www.davidwheldon.co.uk/ms-treatment.html
and the following links from Marie's excellent compilation on our Research page:
CPn and Cardiovascular Issues
We have so many links to cardiovascular issues that these are now found on their own page here. Please do read this material even if you are here for something other than cardiovascular problems! While you may be on this site for MS, CFS or FMS, it is the cardiovascular research that has all the depth and impressive volume about CPn and how it causes human disease that makes the picture truly clear. Don't make the mistake of thinking this is some new idea or that it has only a few studies just because it is relatively unknown in one field. This is as significant to human disease as understanding staphylococcus, only we are talking in this case about chlamydia pneumoniae. Information about the germ applies and transfers from one field to the next: the important thing is to understand the pathogen.
CPn and Arthritis:
-Antibiotic treatment of arthritis Osteoarthritis when treated with doxycycline has significantly reduced joint space narrowing 40% better than controls.
Persisitant CPn and Arthritis Great paper overviews the concept of CPn and C. trachomatis as causitive agents in arthritis.
CPn and Respiratory disease:
Mechanisms of chlamydiophilia mediated GM-CSF release in HUman Bronchial cellsHow does CPn tirgger inflammatoin in lung tissue? this attempts to pinpoint the answer
Serum IgG and IgA antibodies to CPn in EmphysemaThis article indicates that serology is positive in emphysema and that clinical course and worsening is tied to CPn status
Asthma and CPn. Explains interaction of patient immune system with the CPn. Technical.
-Cpn in recurrent respiratory infections This work with children with recurrent respiratory infections indicates that treating for cryptic bacteria improves outcomes. Treatment was prolonged due to the nature of cryptic, or "atypical" bacteria.
Chlamydia Pneumoniae and COPD This reserach indicates that acute exacerbations of COPD re associated with CPn.
-Cpn in asthma This research indicates that cryptic bacteria play a role in asthma. Outcomes were improved by adding abx.
CPn and other diseases:
Behcets may be CPn related. A disease traditionally thought to be autoimmune is found to have significant titers of CPn.
-Cpn in prostate pathology This research found CPn in prostates with pathology. It even offers the theory that patholgy from hypertrophy to cancer represents different stages of infection. -Chlamydia Pneumoniae in Interstitial Cystitis Is IC a mystery disease or is it a bacteria? This paper outlines the results of research investigating this.
Interstitial cystitis and CPn Link out to paper on this subject.
-Chlamydia pneumoniae in the Alzheimer's brain varies with APOE genotype The APOE genotype apparently interacts with CPn in alzheimers patients carrying that genotype. This suggests an interesting theory: that a bacteria is not the same in every person in terms of effects but rather an interaction between genes and bugs results in the pathology an individual experiences. This is a whole new understanding of how we interact with our environment.