Cpn confirmed in molecular mimicry and MS
The developer of EAE as a research tool for MS treatment research speaks out about it's reliability as a test for humans.
example 1/. Molecular mimicry is a possible explanation for autoimmune side effects of microorganism infectionsi.
example 2/. The relevance of any of these sequences to human disease, and particularly to MS, is questionable. The only way to determine whether any of these sequences are encephalitogenic in humans is to inject humans. This, of course, is not feasible. Many of the encephalitogenic regions are capable of reacting with activated lymphocytes from MS patients. However, this is no proof that they can induce disease in humans. Without reviewing this topic, five pertinent papers can be cited.
see table 2
Cpn is a bacteria able to mimic