Cpn and Hyperparathyreodism ?

Does anyone know if Cpn (or other chronic infections) can cause hyperparathyreodism ? My blood levels of calcium are usually borderline high, phosphate borderline low or too low. Last week I tested parathyroid hormone, this was also elevated. I do have kidney stones and frequent urination. So it seems that I have hyperparathyreodism, although not confirmed through a MD yet.

Are you taking vitam D supplements? If yes, vitamin D overdose would be one probable cause

But in chronic infections the whole vitamin D metabolism (and thus calcium, phosphate, PTH) are dysregulated via the vitamin D receptor (VDR). There is some controversy, if vitamin D should be supplemented or not in chronic infections. The paper that I linked argues for the use of olmesartan (VDR agonist) to correct for this dysregulation

Jacck, the second link you give here is written by Meg Mangin, who is or was a moderator on the Marshall Protocol site, well known for disparaging the supplementation of vitamin D and not a favourite of people on this site.  Also, the overdose talked about in the first paper is 50,000 a day taken for several months, and even then it was not found to be common.  That is way beyond what is recommended here.....................Sarah

Completed Stratton/Wheldon regime for aggressive secondary progressive MS in June 2007, after four years, three of which intermittent.   Still improving bit by bit and no relapses since finishing treatment.

@ Jacck: I don't supplement Vit D. It is in a good range, even in winter, probably because PTH does also increase Vit D concentration. Next week I'll see my doctor and probably she'll send me to an endocrinologist/radiologist to see if my parathyroids are increased.

I still think that my hyperparathyreodism is a result of my overall poor health. I am male and 32 years old, HPT is uncommon in young males. So I think it must have something to do with my chronic infections which I have for at least 20 years now. This is important, because normal therapy would be a surgery and I really would skip that ...

Yes, it is not vitamin D overdose. In that case, PTH would be lower than normal and not higher.

It should be ruled out that you do not have a parathyroid adenoma or something like that (primary hyperparathyreodism). A simple ultrasound should rule that out.

But the more probably explanation is that you have a secondary hyperparathyreodism caused by vitamin D deficiency. Higher PTH means, that your vitamin D levels are low and PTH tries to compensate. That also releases calcium from the bones. That is to be expected in chronic diseases. If it lasts 20 years, you could also have osteoporosis.


I would check vitamin D levels in blood and do a ultrasound of the parathyroid glands. You should probably start supplementing vitamin D, if the primary hyperparathyreodism is ruled out