13 Mar 2020
Author
Cesare
Title

Can NAC cause harm and protect cancer cells?

Body

Hi to all! I was worrying about the following posts.

Does NAC not only protect good cells, but also protect cancer cells?

So could it be dangerous to take NAC?

Anybody else worying about this topic?

Any input and knowledge is much appreciated.

https://blogs.sciencemag.org/pipeline/archives/2019/10/04/n-acetyl-cyst…

 

Comments

One thing about mice is that they get cancer really easily.  Mice are short-lived animals that lack many of our defenses against cancer.  So causing cancer in mice isn't great cause for alarm.  And inflammation, such as is caused by a Cpn infection, is itself something that contributes to cancer.  So this really shouldn't stop anyone from using NAC to augment an antibiotic protocol.

Taking NAC for the rest of your life prophylactically, however, is another matter.  Besides the cancer possibility, there was a study recently that found that NAC actually helps EBs infect cells.  (That must be a timing and concentration thing: if the EB is exposed to enough NAC for long enough it'll destroy the EB, but if it's just exposed a little, it will just loosen the outer shell a bit and help with infection.  Not a problem when antibiotics are given at the same time, but possibly a problem when taking NAC on its own.)

Also, NAC is an agent that breaks disulfide bonds, and the body itself uses disulfide bonds for all sorts of purposes; they're one of the main things that give proteins their shape.  Going around breaking them willy-nilly doesn't seem like the greatest idea.

I really appreciate your thoughtful reply to Cesare's query about the article he linked to.

It certainly helps me re-think how/if I will be taking NAC after I'm done with the CAP.  

Jan

56 y.o. with possible dual diagnoses that I am working to confirm this year: Ankylosing Spondylitis and Scleroderma, and minor Psoriasis.

Hmm... presuming you're referring to the JCI Insight study under discussion here, the only figure they seem to give is "NAC 40mM added to the drinking water".  I know how to get from moles to grams, but not how to figure out how much water their mice drank.

In any case, thanks for the reminder to always check the doses, since they're so often unrealistic yet with their unrealism being completely ignored.

D W

Norman is right. Mice ain't men. Look up the Mouse Bittner Factor. There isn't a human parallel.

D W - [Myalgia and hypertension (typically 155/95.) Began (2003) taking doxycycline and macrolide and later adding metronidazole. No medication now. Morning BP typically 110/75]

Hi everyone,

Sorry I have been away for a while. There has been a lot going on in my life! But now I’m back… I haven’t looked at the site for some time, and I’m obviously out of date.

I hope you’re all well? Neena, how’s Sonal? Kiki? Jan? Sarah?  I’m fine, trying  very to get back to NZ to see my elderly parents. It’s hard. 

To let you know what’s been happening – I had a sudden work offer and started a busy new contract for a new client, so  I was working from early in the morning until late at night. iPhone off during the day . 

Before I had started taking amino acids which apparently would make a difference to my recovery. At first, they seemed to. I get so damned impatient.

But last week, on the same day that my fab contract was suddenly stopped (coronavirus), I recognised that my walking had deteriorated quite a bit. I managed to fall over twice in public (so embarrassing). I stopped amino acids.  I can feel the improvements but I’ve gone back 2 months. I could kick myself (with my left leg, not right...). 

All is well, back at home. 
😊

Bye bye everyone! 
Best wishes,

Lizzie xxx

Elizabeth Anne

Thanks for giving us all a catch-up!

I'm sorry the AA didn't work out as planned.   

Right now we are all staying at home... husband working from home (this is usual), daughter (home from Iceland, doing college work online, visiting friends online...), and me, doing a bit of gardening and working the protocol.

I've been experimenting more with Agmatine... many autistic people have low levels.  It seems to be helping in reducing overall inflammation. It is definitely helping with Psoriasis (on elbows)  For everyone with MS, there is some indication it might be useful:  https://www.ncbi.nlm.nih.gov/pubmed/?term=agmatine+and+multiple+sclerosis  and

http://oaji.net/articles/2017/1330-1532592516.pdf

 

Cheers,

Jan

 

 

56 y.o. with possible dual diagnoses that I am working to confirm this year: Ankylosing Spondylitis and Scleroderma, and minor Psoriasis.

Hi Jan,

Yes - we’re locked in here as well. It’s surprising how occupied I can make myself with planning meals and listening to radio dramas. Small mind!
 

Thanks for the link. Following the AA debacle I’m sticking to the usual vitamin supplements for now. I am trying to walk a mile each day and will try for a longer walk in the weekend. I’m holding to weekday and weekend practice for now, so that when (if) life gets back to normal it will be easier. 😉

Best wishes,

Lizzie

 

 

Elizabeth Anne

Hi Lizzie

where are you in Britain or Spain? good to hear you can do a mile walk easily. Has restarting the protocol worked or working for you? Sonal is much the same. No deterioration but not much improvement either. I n between she had shingles/ herpes and that put her back. She just finished her tenth pulse, quite nicely. Not too much fatigue and nausea.

Keep in touch

Neena

I am 76 years old. My daughter-in-law was diagnosed with MS and we are all very keen for her to start this new antibiotic treatment. We hope to be able to do this in the next couple of weeks by finding a doctor willing to deal with any issues like reactions that may crop up. My daughter-in-law is 43 years old.

I have been an active poilitical journalist most of my life and have felt for a long time that there must be a cure out there for MS which the medical community has largely ignored. I am very excited by the Wheldon protocol.

Hi Neena,

It’s good to hear from you. We’re still in the UK. Our flat didn’t sell and now I don’t think it will for ages. Spain’s a bit of a disaster zone anyway! Things are improving again, but it was a proper relapse . I put it down to Amino Acids but who knows? I’ve stopped taking them and I'm on the first day of a pulse. 

How are you doing in the lockdown in India? I seem to spend a lot of time reading. I can  recommend “On the Trail of Genghis Khan” - outstandingly goodAnd reading blogs! James Howard Kunstler is brilliant. Not to forget BBC Sounds back catalogue.

Best wishes to everyone. Keep safe!

xx

Lizzie

Elizabeth Anne

Hi Liz

Yes good to hear you are still in UK which is currently much better placed than Spain, where the virus seems to be everywhere. Keep safe and keep well. Your relapse should get under control. You must think of doing the protocol for another year maybe and then back off gradually, doing a pulse every second month, then every third month and so on. I think this is what Sarah and David have recommended anyway.

I am still hoping that with the first year gone in steadying the arresting decline, Sonal's second protocol year will see some improvements. Currently with the lockdown she may start running out of supplements as Amazon supply chain is broken despite government promise that e commerce will be allowed to carry on. Keeping fingers crossed. But she has her antibiotics, so that is taken care of. What about your meds?

Take care

Neena

I am 76 years old. My daughter-in-law was diagnosed with MS and we are all very keen for her to start this new antibiotic treatment. We hope to be able to do this in the next couple of weeks by finding a doctor willing to deal with any issues like reactions that may crop up. My daughter-in-law is 43 years old.

I have been an active poilitical journalist most of my life and have felt for a long time that there must be a cure out there for MS which the medical community has largely ignored. I am very excited by the Wheldon protocol.

Hello everyone,

Thanks for your kind words Neena.

I’ve noticed improvements are back on track again. I’m in the middle of a pulse. With the CV restrictions I’m only walking short distances during the week, but it’s definitely better. I’ve still got some way to go, but it’s in the right direction. Thank goodness. 

Bye for now,

Lizzie

Elizabeth Anne

Hey Lizzie.... glad things are on the upswing with the protocol.  I need to start walking again like you!

Cheers,

Jan

56 y.o. with possible dual diagnoses that I am working to confirm this year: Ankylosing Spondylitis and Scleroderma, and minor Psoriasis.

good to hear Lizzie. But dont stop too soon, phase it out gradually when you are ready as the protocol itself suggests and one year not good enough for all, although it was for Sarah.

Just the other day Batgirl said she did abx more on than off for 13 years or something like that.

I am hoping that Sonal will be better but will take a year or two longer. Take care

Neena

I am 76 years old. My daughter-in-law was diagnosed with MS and we are all very keen for her to start this new antibiotic treatment. We hope to be able to do this in the next couple of weeks by finding a doctor willing to deal with any issues like reactions that may crop up. My daughter-in-law is 43 years old.

I have been an active poilitical journalist most of my life and have felt for a long time that there must be a cure out there for MS which the medical community has largely ignored. I am very excited by the Wheldon protocol.

Dear Kiki

how are you doing in the lockdown time? Are you able to cope with the children home and schools closed. But I suppose your husband must also be working from home as most people are here.

Drop a line if you can. Sonal braves on not any significant improvement in mobility, but generally she feels fine.

Neena

I am 76 years old. My daughter-in-law was diagnosed with MS and we are all very keen for her to start this new antibiotic treatment. We hope to be able to do this in the next couple of weeks by finding a doctor willing to deal with any issues like reactions that may crop up. My daughter-in-law is 43 years old.

I have been an active poilitical journalist most of my life and have felt for a long time that there must be a cure out there for MS which the medical community has largely ignored. I am very excited by the Wheldon protocol.

Hi Neena!

Yes we're all safe and well together at home. Minimum of outings bar dog walk and food shop. Weather is turning lighter, sunnier and warmer so more days in the garden . Lucky us as ours is fairly large and away from neighbours. I planned ahead and got 6 months worth of meds shipped before it went too crazy so fingers crossed I'm sorted for most of all our lockdowns!

I'm still no better as far as much improved physically but I also realise I've let go of much physical activity since Sept last year which hasn't helped so I've worked out a mini workout for myself that I do twice a day to improve my body plus doing the chores of laundry, hanging it, washing dishes and making beds up etc. It really has helped me and I can now do more of the sets and more repertitions so slowly slowly catch a monkey..

See if Sonal can start doing tinsy muscle strengthening moves in bed for ex. I do mine when I wake up and later on in the afternoon before dinner. 

If no MS physio around then maybe even look ar exersises and programs for re building muscles and moves that stroke patients get. Often they get given tiny moves programs in order to gain larger movements (so to rebuild previous things they could do before a stroke). Also smaller Pilates moves as that was created for ballet dancers recoveries after injuries. 

I just figured the longer I dont encourage muscles the worse I get.

Much love

Kiki🙂

 

You sound great and well-prepared for the lockdowns.   I'm glad you're moving more and that it is helping. 

I am jealous of your large garden (it's largeness and distance from neighbors).... I live in a very tight neighborhood with five neighbors over all my garden walls.   No grass of course, just gravel, but I do have quite a few plants and my composting is going well.

I have been thinking about Pilates for several years now to rehab all my muscles.... have you done this long?  I hear that it is very effective in re-building the body.

We will be in the 80s (F) today... not much spring these days.  We seem to leap from our mild winters straight into the furnace.

Cheers,

Jan

56 y.o. with possible dual diagnoses that I am working to confirm this year: Ankylosing Spondylitis and Scleroderma, and minor Psoriasis.

Hi Jan!

Ive always known Pilates was invented for pro ballet dancers to recover from injuries. Theres all sorts of programs but Ive only evrr done restorative ones when I needed due to back injury( slipped discs) and knee surgery ( ACL  reconstruction). Its lots of tiny small exercises to build up core, strength and suppleness. So tinsy and controlled movements where one would be a fool thinking it wont make a difference but it DOES!! Id say much gentler and appropriate for older body than yoga. All depends too on a great teacher. Its deffo the way I feel for me and Ive done much more yoga in the past. Yoga is a young persons game unless youve always done it.

Theres much more of finer calculated moves within pilates for me.

Google some restorative due to injuries sessions maybe. I also find Kundalini yoga brilliant for mentally fortifying and building me up emotionally. Its more an uppimg and releasing energy thing for me than pure physical aerobics.

Love 

Kiki

 

 

Yes Kiki

good to hear all well as fas as this dreadful pandemic is concerned. I do keep telling Sonal that she must exercise her muscles even while in bed, legs and hands can be effectively done while in bed.

Here the lockdown quite complete. In last 15 days i stepped out just once yesterday to buy some cheese and other odds bits.

More later. Keep well,

Neena

I am 76 years old. My daughter-in-law was diagnosed with MS and we are all very keen for her to start this new antibiotic treatment. We hope to be able to do this in the next couple of weeks by finding a doctor willing to deal with any issues like reactions that may crop up. My daughter-in-law is 43 years old.

I have been an active poilitical journalist most of my life and have felt for a long time that there must be a cure out there for MS which the medical community has largely ignored. I am very excited by the Wheldon protocol.