13 Dec 2019
Author
tuftyone
Title

Veins and blood circulation

Body

It’s becoming clear to me that my main problem is blood circulation. This is causing my disability; my left leg and left side effected more than anything else. I’m wondering if anyone knows how CPN affects veins and arteries, or if you could point me towards other articles and information. I’m wondering if treating with antibiotics will actually reduce these problems or whether the subsequent damage to the veins is actually irreversible. Any thoughts or comments would be very useful 

 Hope you’re all well! 

Comments

Some articles about Chlamydia pneumoniae and fibrosis:

 

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3156096/

 

https://tinyurl.com/ug3bpdk

 

In addition to the CAP, I use proteolytic enzymes to reduce fibrosis in my body:  Nattokinase, Serrapeptase, and Lumbrokinase.

 

  1.  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372539/
  2. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372539/
  3. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3879341/

 

  1.  https://www.ncbi.nlm.nih.gov/pubmed/31482506

 

  1.  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3876685/

Cheers,

Jan

56 y.o. with possible dual diagnoses that I am working to confirm this year: Ankylosing Spondylitis and Scleroderma, and minor Psoriasis.

Hi Jan - Which brand of these proteolytic enzymes are you using?  These enzymes are poorly absorbed in the intestines due to their large molecular weight (45 - 60 kDa).  So, formulation can make a big difference, and different brands use different formulations.

Hi!  Sorry I didn't see the responses to the links I posted until today.

I use Doctor's Best for all three enzymes:  Nattokinase, High-Potency Serrapeptase and Lumbrokinase.

I use a lot of brands of supplements, but have found Doctor's Best to be good, even with excipients.

I started with Nattokinase:  taking one capsule a day on an empty stomach.  I made the mistake of having some food first (contrary to the directions) and was pretty nauseous for about a 1/2 a day.  So be careful.

When I have time, I think I will experiment with taking them sublingually. 

I am still working on increasing doses for all three.  

 

Jan

 

56 y.o. with possible dual diagnoses that I am working to confirm this year: Ankylosing Spondylitis and Scleroderma, and minor Psoriasis.

Hi Jan,

What are these enzymes for? I dont think Sonal takes any. She has stuck to the supplements recommended on Wheldon Protocol. Nothing much else. So please enlighten me. Who recomme nded and what are these expected to do for you?

Good to hear you are progressing slowly but surely. Belated Merry Xmas and i raise a toast for a healthful new year.

Neena

I am 76 years old. My daughter-in-law was diagnosed with MS and we are all very keen for her to start this new antibiotic treatment. We hope to be able to do this in the next couple of weeks by finding a doctor willing to deal with any issues like reactions that may crop up. My daughter-in-law is 43 years old.

I have been an active poilitical journalist most of my life and have felt for a long time that there must be a cure out there for MS which the medical community has largely ignored. I am very excited by the Wheldon protocol.

Hi Jan!  I did some experimentation with 2 brands of Serrapetase enzyme: Doctor's Best (120,000 SPU) and Ericsson's (80,000 SPU).  I had never taken an enzyme supplement before and did not know what to expect.  All I know is that these enzymes are very poorly absorbed.  I first took a capsule of the Doctor's Best when I first woke in the morning on an empty stomach and washed it down with 2 x 8 oz. glasses of water.  I did not feel anything, and did not expect to feel anything.  On the next morning, I took a capsule of Ericsson's and washed it down with 2 x 8 oz. of water.  This time, I felt a very slight pain narrowly running along the left side of my neck in the location of the carotid artery.  Was this from Serrapeptase working its magic?  I don't know.

So, I repeated the experiment again: first with Doctor's Best and then with Ericsson's.  It did repeat!  No feeling with Doctor's Best, but very slight pain again with Ericsson's.  It is possible that the Doctor's Best is absorbed too slowly to feel anything due to the Serrateric formulation.  The Ericssson's is not specially formulated and is probably absorbed quickly.  With any formulation of these enzymes, if 5% is absorbed, then that is probably as good as it gets.

I tried a third experiment.  When I woke, I took 4 Doctor's Best capsules (4 x 120,000 SPU).  The only thing that I felt was a slight headache!  On the next morning, I took 2 Ericsson's, and again get the same slight pain running along the left side of my neck close just below the skin.

I then did some research on both of these companies.  I really should have done the research before I bought.  I find out that Doctor's Best is a Chinese company!  That was a surprise to me.  Serrapeptase was the first Doctor's Best product that I had ever purchased and it will be my last.  I occasionally outsourced work to Chinese companies when I was Director of Medicinal Chemistry in the pharmaceutical industry.  They are not trustworthy.  A 'Certificate of Analysis' from them means nothing. Ericsson's is a Swedish company, but they are not much better.  They are a small company, not very transparent, and seems that the Serrapeptase product is being phased out because it is no longer listed on their website.

So, I will continue the quest and try some other brands.

Hey Scott--

Thanks for sharing your experiments/trials with Serrapeptase/trying different brands.  

I appreciate the update about the buyout of Dr.'s Best by a Chinese company.  But unless I send a sample of each proteolytic enzyme I take to an independent US lab for quality assurance (more money), I'll just have to trust (ha!) the product.

While taking them, I have noticed a significant improvement in my chronic sinusitis problems since starting taking it.  Whether or not it is truly helping with any fibrosis I have, I don't know.   

I will probably continue with Dr.'s Best Nattokinase, Serrapeptase, and Lumbrokinase while I am on the CAP.   It might help.... maybe quite a lot, and I have had not had any noticeable/intolerable side-effects. 

Also, I would urge caution if you notice any pain while taking the enzymes.  An article I came across might interest you:  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5028551/

If you do decide to continue with your experiments, have a look at Bulk Supplements' Nattokinase:

https://www.bulksupplements.com/products/nattokinase-powder?_pos=1&_sid=5111fc7a8&_ss=r

I'm not sure, but they might do an independent quality analysis of all the supplements they import from China.

 

Cheers,

Jan

 

 

 

 

 

 

56 y.o. with possible dual diagnoses that I am working to confirm this year: Ankylosing Spondylitis and Scleroderma, and minor Psoriasis.

Tufty, I have just seen this as well. I presume you know that with MS, one side of your body is likely to be affected more than the other? With me it was my right side, and even now my right leg and arm are slightly weaker than my left.  This is because most people have lesions more on one side than the other.  However much the enzymes may work you are still likely to end up with more weakness on your left side.  Hopefully, as with my right side, not enough to really hinder you  too much from doing most things.

Proteolytic enzymes do sound as if they might be well worth a try.  I already take serrapeptase as an aid to menopause symptoms sometimes, so I think I will look into it more.

Completed Stratton/Wheldon regime for aggressive secondary progressive MS in June 2007, after four years, three of which intermittent.   Still improving bit by bit and no relapses since finishing treatment.

Tufty - I'm not at all sure why you are suspecting your problems are caused by circulation problems.  My left side is more affected than right - with weakness and loss of sensation - but mine is all neurological and abx help resolve this.

Neuro symptoms & many health problems from 1989. NAC+all supps(04/11) CAP(05/11-10/17)

Sarah

Sonal has quite a major problem with spasticity in her legs. This more than anything else makes it sifficult for her to walk. Her legs sometimes become very stiff and she is unable to bend at the knees when trying to sit after walking with a walker a short distance.

She has mush reduced the dose of meds she was taking for spasticty recommended by her neuro years before the protocol was started. Now she takes a quarter of the dose she was taking earlier. She has reduced it slowly -- first halved then quarter.

Neena

I am 76 years old. My daughter-in-law was diagnosed with MS and we are all very keen for her to start this new antibiotic treatment. We hope to be able to do this in the next couple of weeks by finding a doctor willing to deal with any issues like reactions that may crop up. My daughter-in-law is 43 years old.

I have been an active poilitical journalist most of my life and have felt for a long time that there must be a cure out there for MS which the medical community has largely ignored. I am very excited by the Wheldon protocol.

I remember that Sonal had begun to fall over when walking. Since I knew she was on baclofen, which is taken to aid spasticity and I knew of other people who were on it and this had happened when taking the treatment, I suggested that she lower the dose. Her walking improved.

I was somewhat spastic when I started the treatment, though not on baclofen.  The spasticity gradually disappeared.

Sarah

Completed Stratton/Wheldon regime for aggressive secondary progressive MS in June 2007, after four years, three of which intermittent.   Still improving bit by bit and no relapses since finishing treatment.