MediTest
Submitted by Jan Figtree2019 on Sat, 2019-08-03 13:54

I finished 6 Pulse yesterday (Friday, August 3rd).  This pulse was five (5) days of Tinidazole. I kept it to five days because I was experimenting with taking Serrapeptase along with it.  

 

Serrapeptase is a proteolytic enzyme.  It is useful in many areas of medicine.  I am trialling it to see if it helps reduce inflammation.  I also think it might be useful in helping the antibiotics penetrate more deeply into my tissues …. With Scleroderma the thickening of all my tissues has been a concern for me ... The excess collagen might prevent some?/most? of the nutrients + meds + vitamins + minerals being thoroughly absorbed in my gut.  

 

I started Serrapeptase slowly about a week before this last pulse.  I am at 80,000 SPU. I did not have any interactions with the antibiotics that I could observe.   I am going to continue to increase the dose to at least 120,000 SPU. Additionally, I want to add Nattokinase and Lumbrokinase to the group.

 

Back to the Tinidazole:   I had some extra fatigue this Pulse, but largely felt OK.  One day I simply had to go to bed very early (6 pm) as I couldn’t hold my head up any more.  Psychologically, I only had one day when I felt low, and told my husband it was the Tini…. And that was it.  Luckily I did not have to interact with anyone that day.

 

I exercise indoors with my cheap rower which has actually been brilliant for working out.  I vary the length of the workouts. I really like how it keeps me out of the desert heat and dust.  I sew to keep my mind occupied.

 

I continue to take all supplementary vitamins + minerals + supps. I did not increase my N-A-C before starting this pulse because I chose to trial the Serrapeptase instead.   Hopefully, I will be able to add this last dose in the next month or so.

 

Gut health:   I take plain yogurt everyday with a handful of various probiotics everyday well away from antibiotics.

 

Ketogenic diet:  I continue with this of course, and I think this is a key player in returning to robust good health…. It certainly is helping with inflammation and gut health.

 

Scleroderma:  I continue to see reduction in skin thickness all over my body as well as softening and increased elasticity.   The reductions are tiny, but that is OK … it is progress. I continue to see a lightening of my skin in places where the scleroderma had darkened it.  I see more veins in my hands where the excess collagen has been thick and noticeable.  Torso stiffness/rigidity is still an issue, but slowly improving... the rowing I do helps exercise some of the muscles in torso.

 

Ankylosing Spondylitis:  Curiously, this pulse I had two incidents of sharp, intermittent pain in buttocks area… right near base of spine.  It surprised me, but thankfully it went away quickly. It also reminded me of why I am doing all this…. Pain is shit.   

 

Psoriasis:  (only on elbows):  Still healing. The affected areas are diminishing in size and scaliness.  Slow but good.

 

Activated Charcoal to mop up all the debris:  I try to take it at night away from everything else, but since my sleep has been improving I am not getting up as frequently….. So I let it slide.  Sleep is paramount!

 

That’s it for now,

Jan

Blog comments

Jan, it is fascinating reading your posts and I am so glad that what you are trying seems to be working for you.

You are right about sleep being paramount though, so if you are managing to get more sleep, activated charcoal is bound to suffer.

One thig to remember about NAC though: David only brought it into his protocol to kill any elementary bodies, so while you are on abx full-time, you could do without taking it.  It will come into its own when you move on to intermittent protocol.

Completed Stratton/Wheldon regime for aggressive secondary progressive MS in June 2007, after four years, three of which intermittent.   Still improving bit by bit and no relapses since finishing treatment.

Hey Sarah!

Thanks for your comments.  It's good to know I could stop the N-A-C until I am done with the CAP.  I also take N-A-C for my autism.... it reduces my irritability... :-) bonus for my family.

N-A-C also works to break down biofilms ... something I've been working on for a while:

Just an example:  https://www.ncbi.nlm.nih.gov/pubmed/25339490

 

Cheers,

Jan

 

 

56 y.o. with possible dual diagnoses that I am working to confirm this year: Ankylosing Spondylitis and Scleroderma, and minor Psoriasis.

Ps. Sarah

What do you mean activated charcoal suffers if you have longer/ more sleep? And also what "wasteage" is NAC  doing whilst on full time ABX ie does it serve no purpose then/ or poss disadvantages of taking it then?

Kiki

Kiki, what I meant was that if Jan is getting more sleep now, her taking of activated charcoal is bound to suffer since she took it mainly at night when she woke up.

 As for NAC, people take it for many reasons other than killing elementary bodies and should continue to do so!

Completed Stratton/Wheldon regime for aggressive secondary progressive MS in June 2007, after four years, three of which intermittent.   Still improving bit by bit and no relapses since finishing treatment.

Hi Sarah

I was just wondering as I always take it ( charcoal)before going to bed having thought it can do its thing whilst Im asleep and resting. So thought now maybe not a good idea anymore thats all.

Kiki💖

Dear Lizzie

wanted to ask you how much biotin do you take and when in your treatment did you increase dosage? Sonal, I think, is currently taking 5 mg ((beware of confusion between mg and mcg) three times a day. I think this is the dosage recommended on the Wheldon protocol. 

But are you taking much more like 100 mg which I think Sarah is taking more recently long after her Abx protocol ended.

are you already in Spain or in the process of moving? Keep in touch.

 

Neena

I am 76 years old. My daughter-in-law was diagnosed with MS and we are all very keen for her to start this new antibiotic treatment. We hope to be able to do this in the next couple of weeks by finding a doctor willing to deal with any issues like reactions that may crop up. My daughter-in-law is 43 years old.

I have been an active poilitical journalist most of my life and have felt for a long time that there must be a cure out there for MS which the medical community has largely ignored. I am very excited by the Wheldon protocol.

Neena, I had a look at David's site and he mentions the Sedel, Papeix and Bellanger trial where doses of 100 -300 micrograms were given. I am taking roughly 200 micrograms a day but some people on the original trial took up to 500 micrograms a day.

Completed Stratton/Wheldon regime for aggressive secondary progressive MS in June 2007, after four years, three of which intermittent.   Still improving bit by bit and no relapses since finishing treatment.

Sarah

i thought the high dose trial talked about 100 to 300 mg with I suppose 1000mcg equal to 1 mg. I  am totally confused. Sonal is currently taking a total of 15 mg a day, a 5 mg tablet x 3 times a day. Sarah should she up the dose at this stage or later? She is now on her third day of the second pulse and doing fine in terms of no serious adverse reactions. 

100 mg would mean 20 tablets of 5 mg a day!

neena

I am 76 years old. My daughter-in-law was diagnosed with MS and we are all very keen for her to start this new antibiotic treatment. We hope to be able to do this in the next couple of weeks by finding a doctor willing to deal with any issues like reactions that may crop up. My daughter-in-law is 43 years old.

I have been an active poilitical journalist most of my life and have felt for a long time that there must be a cure out there for MS which the medical community has largely ignored. I am very excited by the Wheldon protocol.

Neena, I take about 20 tablets a day, but they are very small, otherwise I would buy the powder and put it in capsules!

Completed Stratton/Wheldon regime for aggressive secondary progressive MS in June 2007, after four years, three of which intermittent.   Still improving bit by bit and no relapses since finishing treatment.

thanks Sarah

I looked up David's list of supplements again. This may have been before the biotin trials. He mentions 5 mg twice a day that is equal to  5000 mcg twice a day, which Sonal is taking. If she were to increase to 100mg a day it would mean taking 20 of those 5 mg tablets a day. Sorry to keep at this. But is this correct? And should she up the dose now or later after she has done several pulses. Right now about to end the second pulse, which has so far been ok.

Neena

I am 76 years old. My daughter-in-law was diagnosed with MS and we are all very keen for her to start this new antibiotic treatment. We hope to be able to do this in the next couple of weeks by finding a doctor willing to deal with any issues like reactions that may crop up. My daughter-in-law is 43 years old.

I have been an active poilitical journalist most of my life and have felt for a long time that there must be a cure out there for MS which the medical community has largely ignored. I am very excited by the Wheldon protocol.

Neena, I'm afraid you have got things a bit wrong. I think you are mixing up paragraphs two and four. The following is copied from David's MS site and is dated 2017:

Biotin

Biotin is a water-soluble vitamin. It is thought to be a cofactor in the synthesis of fatty acids, including myelin. A 2015 pilot study of high-dose supplementation in persons with progressive MS showed a surprising improvement in function in those with cord lesions. The authors comment: "Sixteen patients out of 18 (89%) with prominent spinal cord involvement were considered as improved as confirmed by blinded review of videotaped clinical examination in 9 cases." They note that improvement took some time (2 - 8 months) to become manifest. [Sedel F, Papeix C, Bellanger A, et al. High doses of biotin in chronic progressive multiple sclerosis: A pilot study. Mult Scler Relat Disord 2015; 4: 159-169]

The dose used was 100 - 300 milligrams daily. Larger trials are in progress.

Given that biotin is harmless, it would seem prudent to act on these preliminary findings. Pure high grade biotin in 10mg tablets is available. The tablets are small and easily swallowed. Only the pure form, unmixed with other supplements, should be taken.

Here is a comprehensive review: [Sedel F, Bernard D, Mock DM, Tourbah A. Targeting demyelination and virtual hypoxia with high-dose biotin as a treatment for progressive multiple sclerosis. Neuropharmacology. 2016 Nov;110(Pt B):644-653]

Added 25th Jan 2017

Completed Stratton/Wheldon regime for aggressive secondary progressive MS in June 2007, after four years, three of which intermittent.   Still improving bit by bit and no relapses since finishing treatment.

Thanks Sarah,

will persuade Sonal to act on this aight away. I was reading the list of supplements recommended by David where it said 5 mg twice a day. 

I did read about the trials. But I also thought that later somebody else tried to say something different or sort of pooh pooh the trials.

Sonal is today finishing her second five day pulse with metro. So far no major adverse reactions. 

Has anything been resolved for those who need to but antibiotics? Take care

neena

I am 76 years old. My daughter-in-law was diagnosed with MS and we are all very keen for her to start this new antibiotic treatment. We hope to be able to do this in the next couple of weeks by finding a doctor willing to deal with any issues like reactions that may crop up. My daughter-in-law is 43 years old.

I have been an active poilitical journalist most of my life and have felt for a long time that there must be a cure out there for MS which the medical community has largely ignored. I am very excited by the Wheldon protocol.

Neena, when talking about MS, there are always plenty of people willing to pooh pooh anything that talks about anything remotely plausible. After all, it was only a few years ago that I was ripped apart on the British MS Society's site along with Mackintosh on an American site.

Sarah

Completed Stratton/Wheldon regime for aggressive secondary progressive MS in June 2007, after four years, three of which intermittent.   Still improving bit by bit and no relapses since finishing treatment.

Yes Sarah

I all too aware of this having gone down the path of several "natural" remedies and intially the weekly Avonex injections then techfidera etc in Sonal's case and her walking continued to deteriorate. She never had a noticeable attack as it were.

Yes I know I had seen the biotin trials paper and was quite excited. I was only wondering whether she should start on it after most of her infection has been killed, say after six or seven pulses, or alongside abx. That was the confusion. And by the way which BIOTIN do you buy. Here I am able to find 5 mg tablets. Others with 10 mg strength are mixed with calcium, vitamin C or something else. Which ones are good as PURE BIOTIN? Please help

Neena

I am 76 years old. My daughter-in-law was diagnosed with MS and we are all very keen for her to start this new antibiotic treatment. We hope to be able to do this in the next couple of weeks by finding a doctor willing to deal with any issues like reactions that may crop up. My daughter-in-law is 43 years old.

I have been an active poilitical journalist most of my life and have felt for a long time that there must be a cure out there for MS which the medical community has largely ignored. I am very excited by the Wheldon protocol.

Neena, best to buy pure biotin, not mixed with any other supplements, because Sonal doesn't want to end up overdosing with anything. The tablets are mostly taken for other reasons, in only small amounts!

Completed Stratton/Wheldon regime for aggressive secondary progressive MS in June 2007, after four years, three of which intermittent.   Still improving bit by bit and no relapses since finishing treatment.

Jan

with the sixth pulse under your belt as it were, you must be feeling good, at least better. Wow, that is more than one-third the way into full treatment schedule.

carry on the better days may be just around the corner.

Neena

I am 76 years old. My daughter-in-law was diagnosed with MS and we are all very keen for her to start this new antibiotic treatment. We hope to be able to do this in the next couple of weeks by finding a doctor willing to deal with any issues like reactions that may crop up. My daughter-in-law is 43 years old.

I have been an active poilitical journalist most of my life and have felt for a long time that there must be a cure out there for MS which the medical community has largely ignored. I am very excited by the Wheldon protocol.

Every day just a little bit closer!

Cheers, Jan

56 y.o. with possible dual diagnoses that I am working to confirm this year: Ankylosing Spondylitis and Scleroderma, and minor Psoriasis.

by the way there is a site Skipspharmacy in the US that has 100 mg pure biotin tablets quite reasonably priced for those who may be interested.

neena

I am 76 years old. My daughter-in-law was diagnosed with MS and we are all very keen for her to start this new antibiotic treatment. We hope to be able to do this in the next couple of weeks by finding a doctor willing to deal with any issues like reactions that may crop up. My daughter-in-law is 43 years old.

I have been an active poilitical journalist most of my life and have felt for a long time that there must be a cure out there for MS which the medical community has largely ignored. I am very excited by the Wheldon protocol.

Dear Sarah

wanted to inform you Sonal has increased Biotin dose to 50mg a day . She will increase gradually to 100 mg. She is taking three 5 mg tablets three to four times a day. So far so good. Hope she is able to take the high dose without ill effects.

neena

I am 76 years old. My daughter-in-law was diagnosed with MS and we are all very keen for her to start this new antibiotic treatment. We hope to be able to do this in the next couple of weeks by finding a doctor willing to deal with any issues like reactions that may crop up. My daughter-in-law is 43 years old.

I have been an active poilitical journalist most of my life and have felt for a long time that there must be a cure out there for MS which the medical community has largely ignored. I am very excited by the Wheldon protocol.

That's good Neena!

The advantage of taking the little tablets is that you can take a few whenever you feel like it. 

Completed Stratton/Wheldon regime for aggressive secondary progressive MS in June 2007, after four years, three of which intermittent.   Still improving bit by bit and no relapses since finishing treatment.