Day 3 of pulse 25 is well underway. Over the weekend, I had two days of taking the higher dose of Metronidazolei and it continues today with 3 x 500mg, this time in pill form as opposed to the capsule form. I can now say from first hand experience, there is a major difference between taking the capsule form and taking the pill form. The pill form is NASTY. Horrid, horrid taste!
I've started attempting to toss the pill back in my mouth to my throat in hopes of missing my tongue entirely and washing the bugger down. Uggh!! I had it easy with the capsule form! Unfortunately, when my doc increased my dosage, he also increased the amount of pill prescribed so that I get a 4 month supply at a time. Now, all in pill form....yuck!
Needless to say, I'll be sure and ask for the capsule form when I next refill the prescription!
Now that I've whined about metronidazole and its horrid taste, I can also report a difference that I'm unsure whether is due to the higher dose or what exactly. My visible symptoms have been sorely invisible up until recently. With the higher dose, I noticed my urine is much darker then before, quite noticeably darker. This should be a good thing and I hope that it is.
I am a bit more tired lately then I usually am. I don't know if it's from lack of sleeping enough lately, or from the higher dose of Flagyl, or both. Probably the latter. I will endeavor to get more sleep as I really need it.
The heat lately has been troublesome. Heat still affects me negatively. I wonder whether that will ever change. I hope so. When I was a kid, I ran around all summer in heat, no problem. I want to be able to again. So, onward towards that.
Before this pulse, I had been thinking about pulsing INHi with Flagyl. No thank you, this is enough. I think until the Flagyl has little impact, I will keep things simple.
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all my best
John
RRMSii/EDSSii was 4.5, 5, now 6 on Wheldon Protocol (naci, doxycycline, azithromycin, metronidazolei) since 04/12/2006. Added Rifampin 2x150mg/daily 08/19/2007. Added INHi 300mg/daily 03/17/2008 stopped 05/08
I too take the tablet form
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2004 ME/CFSi after undiag/untreated pneumonia. 2007 lyme/babesia. April 08 finally a diagnosis CPN, lyme, babesia, c. pulmoni.
Rifampicin 150mg day, Azith 250mg M/W/F, NACi 1200mg day, Metronidazolei 400mg 2 x day every 4th week.
John- Go directly to
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CAPi for Cpni 11/04. Dx: 25yrs CFSi & FMSi. Currently: 150mg BID Roxithromycin, Doxycycline 100mg BID, Tinii 1000mg/day pulses; Vit D2000 units, T4 & T3
Metroi tastes disgusting!
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SPMSi< Supplementsi & NACi, Doxyi 200 mg, Azith 250 mg 3X/wk, most suppliments, currently Flagyli 1500 mg x 3 days once per month
Thanks Jim, I had not
Thanks Jim, I had not thought about doing that. A friend of mine buys powerdered supplementsi and empty capsules, stuffing them herself. Not a bad idea to do with Flagyli, we're only talking 15 pills a month. Not sure whether there is an inexpensive kit that I could go that would assist in that process. My friend has one. Don't think she has to break pills in half but I'm not sure.
On another note, Flagyl at 500 mg is definitely harder to take then Flagyl at 375 mg. Perhaps part of that is that it's in pill form and doesn't take as long to be absorbed. However, I physically feel much worse on it then on the capsules which I barely notice most of the time. Today, my legs are heavy and have been all day. It's like dragging around concrete trousers and/or boots.
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all my best
John
RRMSi/EDSSi was 4.5, 5, now 6 on Wheldon Protocol (naci, doxycycline, azithromycin, metronidazolei) since 04/12/2006. Added Rifampin 2x150mg/daily 08/19/2007.
Added INHi 300mg/daily 03/17/2008stopped 05/08In lieu of having the
In lieu of having the capsules to wrap around each pill as Jim suggests, I have come up with a method of taking Flagyli that prevents or minimizes tongue contact. I open wide, tilt my head way back, and carefully insert the pills at the back of my mouth, behind my tongue, quickly washing them away! It's worked a couple of times but is a pain.
I have called around to local shops and found one that carries the 000 capsules Jim mentioned. I probably won't have time to get any before the end of my pulse on Wednesday but I surely will get them for pulse 26 and beyond. No sense in doing anything I don't have to (the awkward swallowing method).
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all my best
John
RRMSi/EDSSi was 4.5, 5, now 6 on Wheldon Protocol (naci, doxycycline, azithromycin, metronidazolei) since 04/12/2006. Added Rifampin 2x150mg/daily 08/19/2007.
Added INHi 300mg/daily 03/17/2008stopped 05/08John, I used to smear jam
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The difference between what we do and what we are capable of doing would suffice to solve most of the world’s problems. Mohandas Gandhi
How to self-compound
How to self-compound flagyli capsules:
http://www.cpnhelp.org/node/4747#comment-36114
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Hunter: Don't think - experiment
Hi Mac I
Hi Mac
I remember reading your suggestion some time in the past but had forgotten about it. The jelly/jam approach might work but then I worry about the consequences of ingesting a strong sugar while on a strong abxi, meaning, what happens with candida and other stuff when doing that. I would be inclined to take the gel capi approach instead, but thanks for the reminder.
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all my best
John
RRMSi/EDSSi was 4.5, 5, now 6 on Wheldon Protocol (naci, doxycycline, azithromycin, metronidazolei) since 04/12/2006. Added Rifampin 2x150mg/daily 08/19/2007.
Added INHi 300mg/daily 03/17/2008stopped 05/08The last day of pulse 25.
The last day of pulse 25. Thank God! There has been a marked difference with this pulse versus the 24 that came before it.
When taking Flagyli, I immediately feel my legs burning and/or heaviness. I had some of that before but it's much more discernible now and lasts all day. It doesn't go away.
Consequently, I think that's a good thing. I don't know the full pharmokoenetics of Flagyl but I would expect that if there wasn't infection, I wouldn't feel much of anything. Burn baby burn, lol!
I can't imagine someone going on continuous Flagyl. Holy crap! Go you! I think several people here have done that. Given the reaction I have now, no way.
When I did continuous INHi, it was imperceptible. I had little if any reaction to it that I could discern so given the reaction I have to the 1500 mg dose of flagyl I've been doing, that's like touching a hot stove element and not expecting to be burned. No thanks, I'll take my time.
I'm hopeful that in the intermission between pulse 25 and pulse 26, I'll see some improvements, given the distinct reaction I'm having this time. Ra, ra! Go team, clean those suckers out!
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all my best
John
RRMSi/EDSSi was 4.5, 5, now 6 on Wheldon Protocol (naci, doxycycline, azithromycin, metronidazolei) since 04/12/2006. Added Rifampin 2x150mg/daily 08/19/2007.
Added INHi 300mg/daily 03/17/2008stopped 05/08John- I think you are quite
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CAPi for Cpni 11/04. Dx: 25yrs CFSi & FMSi. Currently: 150mg BID Roxithromycin, Doxycycline 100mg BID, Tinii 1000mg/day pulses; Vit D2000 units, T4 & T3
John - Perhaps INHi
John - Perhaps INHi addition drove some recalcitrant CPNi into cryptic state and now the Flagyli is doing them in. I hope so !
Also - hope you do see some real and measurable improvement soon !
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Daisy - Husband on CAPi 5/07. "When Going Thru Hell, Just Keep Going", Winston Churchill
Daisy
Daisy
Thanks for the well wishes. I have no idea whether INHi was responsible for what you propose but that would be nice. My understanding is INH is a bacteriocidal not bacteriostatic, so I'm thinking it wouldn't generally be expected to do that, it would be expected to kill off Cpni. It's more of an additional axe to swing at Cpn rather then the threat of one, from what I understand. Maybe that's wrong and you or someone else will correct that understanding.
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all my best
John
RRMSi/EDSSi was 4.5, 5, now 6 on Wheldon Protocol (naci, doxycycline, azithromycin, metronidazolei) since 04/12/2006. Added Rifampin 2x150mg/daily 08/19/2007.
Added INHi 300mg/daily 03/17/2008stopped 05/08