NAC

N-Acetyl-Cysteine.Amino acid used as thiol reducer to burst EB phase of Cpn, and supports liver as glutathione precursor.

Dr. Stratton Answers Some Questions:

Submitted by Jim K on Mon, 2006-01-30 22:13

In some recent correspondance with Dr. Stratton at Vanderbilt University, he kindly answered some of the questions which had formed as I've understood more about the combination antibiotic protocol and about Cpn. From the patient's perspective I wanted to correlate some observations about treatment reactions with his deeper understanding about the biology of the Cpn. I'll list the questions I put to him, and then his generous response below.

1.  In an earlier correspondance you had mentioned pulsing the INH band metronidazole together.
        * Why do that rather than take it continuously?
        * My understanding is that INH is one of the anti-replicatives, and the point is to use these continuously to drive the bug into the cryptic phase where it will be obliterated by the flagyl/tini. Does INH act differently than the other antireplicatives?
        * I also understood that we use a dual abx to prevent developing resistance. Why can we use INH alone without developing resistance?