Well so far on this pulse I feel better. I also got my period and am getting relief of stiffness with it. I used to notice  huge release of stiffness sometimes when menstruating now I realize it is only a great relief when I ovulate. Meaning I guess I get the relief in swelling/inflammationi stiffness when I get a surge in progesterone which you get after ovulation. Again I am using transdermal bioidentical progest now at 200mg 3x daily . Progesterone is supposed to help with remylination so lets see what happens. I am trying everything to switch my body from T1 (inflammatory) to T2 (antinflammatory) . So I have added estriol transdermal along woth the progesterone. I am also supplementing thyroid and adrenal.

well i am feeling really sorry for myself in the mobility department cold hands feet and stiff wall walking. My doc has me tweaking my hormones with bioidentical transdermal creams estriol/ progesterone to rebuild myelini and promote t2 anti inflammationi. I am also trying amoural and adrnenal though I have not gotten the correct emounts yet.  Interestingly enough I am not getting heavy die off symptoms as before from abxi. I am taking all my supplementsi. Wow I think it about time for me to see some constant improvements at least in glimpses. It is imposible to exercise when you'rethis stiff and swollen footed and that of couse is what I REALLY WANT AND NEED TO DO. oh well i try everything when do i get to feel better?

Please respond to this . My doctor recommended a thinning of the blood to help the bacteria/viruses be killed more easily also the antibiotic supposedly will work bette and inflammationi decrease circulation increase. I notice this is suggested in lyme protocol anyone familar with this or any comments? barbara

http://renegadeneurologist.com/  correct link dr perlutter discusses abxi vanderbilt protocoli

www.rengadeneurologist.com    a very well known neurologist Dr. David Perlmutter mentions protocol he doesn't quite get the whole thing but woth checking out! Barbara   His website is interesting  his suggested supplementsi have always been similar to ours

I  am scary tight now at pulse 13. Takings lots of vitaminsi oral and iv as well as gltathione and pc. Got so disgusted with tightness that I am back at the hyperbaric again. I have a great hyperbaric in the house it unqestionably  helps with stifness so I back at it 11/2 hours 1-2 times aday until some relief kicks in. Also Taking 20gm of pharmaceutical fish oil to reduce inflammationi. Man it sucks being so stiff I follow the  regime but no relief recently in mobility brain working great though.

oh well barbara

Ok as atightnesss complainer of msi I have made comments on hormones effecting symptoms. Ie change in tighhness during menstrual cycle. Changd in symptoms during pregnancy(improvement) Improvement after orgams.

Sept 2 8 days or  so after pulse.I started to get really tight again 3 days ago. Hmm is this  inflammationi from puslse kill off or just the tightness from raising estrogen levels in later cycle. I know there are deffinately things  could take to reduce tightness from inflamation as it changes with hormones , times of day, heat, etc.I wish I could figure out exactly what to take and have the magic pill to stay loose and mobile. I can't really say that of all the supps and pills I take from this site anything dramatically effects the tightness. Oh I actually felt more limber and energetic during the last pulse which was a real first. I am hoping the looser times will increase. I am going to get mri again later this month. Check on the neck cervical.

Guess this would be pulse 11. Surprisingly I feel pretty good. I am in mid pulse and really quite energetic. i stopped the ldni to see if my spasticity/ tightness would improve. I think it has somewhat. Don't get me wrong I think ldn is great stuff bt with people like me with tightness tendency it sems to increase it. Surprisinly my energy level is up and I am waking earlier. I had some relief in tightness for a couple days over my period. I am tight but not horrible. I am also not sleeping constantly. Roxu 150x2 , doxyi 100x2, flagyli 500x3. Upped the fish oil. Oh deffinately since I started munching the nystatin any urge to urinate issues have disappeared. I hope this is the beginning of an upward trend.barbara

Well the combination of the heat and abxi induced inflammationi has really left me waddling. I just read far and wide , wiggy and minai and I wonder why some of us msi'ers have more mobility issues than others. Why are some improving why some not? I used to get breaks of feeling realitively looser and able to move pretty well but those improved times have stopped as i've continued with abxi. Hmm I take a lot of probiotics, and for the first time I have started to feel like I am starting to get a pre-yeast so I added nystatin. So i upped my magnesium and I can't say I am any loosy goosier though I deffinately go to the bathroom more.  So I reread sarah and katman and they seem to say that tightness does fade. Well when ?

ok finally was getting over the tenth pulse starting to take the thiamine shots which are the only thing that works for spastisity. took rifampin yesterday then doxyi ran out of doxy for my second dose. Therefore I took a bactrim ds. Wow the clarith always has a super strong effect on me. hot and tight ast night. But the weirdest thing is I woke up today bright red all over. I was not in the sun yesterday. I think i walked to the car outside and I walked to cottage behind my house . Maybe outside two min. But my body is red in placs the sun wouldn't even get to. My head does feel hotand I am tighter than yesterday as the thiamin was starting to kick in. What is happening? I don't want to knock myself off.  I am in the ac. Barbara

I just broke a 104 F fFever. I finished flagyl2 days ago. TIred but ok' But whamo took doxyi today almost died. Huge head and neck pain high fevr. Couldn't walk at all. Peed on way to bathroom. Kids got me upstairs. Horriblle. Only up to  break fever. Now back to bed. uggh Could tell this was coming so cld in feet legs., Pleas let this pass Barbara

Well here I am in the 10th pulse of flagyli. I am tighter than ever and my right hand is somewhat constantly tight. (I can stil type my writing is pretty sloppy off and on but still functional. It gets worse in the couple hours after taking doxyi) my left hand is a little tight on outer perimeter. Walking pretty stiffy and short distances but still getting about . Not using cane particularly except keeping in car for extreme heat and balance. The heat does not help. I still get a feverish feeling after taking 200mg of doxy. I still get fevr and exhausted after flagyl. Mt urine is dark brown with flagyl still.

have decided that I get much more response with rifamp and azith than the bactrim ds doxyi I am using. Also with the 44ap I found that though it made me less tight initially it made me several times tighter as it wore off and before taking it it in am. In fact so tight my feet and calves were painful. I also think it was making me nauseous or maybe combination. Question can I use rifamp and doxy or bactrim until I get more azith. Also I have been geting herper breakouts and am thinking of trying valcyte. perhaps will up d from 4000. Spasticity/gait still biggest issues. Looking for suggestions look all I know I am not progressing but mobility not greatly improving barbara

9th pulse My walking still drunken. I have not had the neck pain this last month but I have the stiff hand I did not have when starting. My tightness is helped by 4ap but still waddling. I am going to start bactrim next week. I need to walk more on treadmill but soo hot.  Again the mind is doing great. This is my eigth month I keep looking for vast mobility improvements. It comes to the point with businesses that you ask yourself how much better am I going to get or should I scale down or keep my expansion plans with the idea being as I improve I will be able to handle more. Hmm at least I am definately not progressing. This is going to be a super hot summer in nj. Barbara