27 Apr 2018

Biofilm and Cpn (also drug resistant Cpn)


Hi!I have started to read up on the role biofilm has on infections, and found this article about biofilm and Cpn.http://www.ijper.org/sites/default/files/10.5530ijper.50.2.22.pdfBacter…, viruses, fungus and parasites may all produce biofilm which they use to reproduse and grow in number, and also to communicate with each other. If biofilm is redused they will have more struggel reproducing and communicating.


Your paper is about Klebsiella pneumoniae which is an extracellular pathogen and has nothing to do with cpn.If you want to see how a borrelia biofilm looks like, here. It is a like a city for bacteria where they are protected. Intracellular pathogens like cpn probably do not make biofilms.Neem can destroy biofilms, here, here


The study you quote involves Klebsiella pneumoniae, not Chlamydia pneumoniae. The former is a free-living member of the enterobacteriacea. It is usually non-pathogenic, but it can cause serious illness, particularly in immunocompromised people. It can cause hospital-acquired infection. It is non-motile. It is easy to grow and is readily identifiable using simple tests. One characteristic which makes it unusual is that it often produces enormous amounts of extracellular slime. This helps it avoid host defences and makes a very efficient matrix for biofilms. Here is a link: http://www.bacteriainphotos.com/Klebsiella%20pneumoniae%20on%20MacConkey.html Chlamydia pneumoniae, conversely,  is only active intracellularly. Slime would probably actually prevent its approach to susceptible host cells. C. pneumoniae is very difficult to grow and few laboratories attempt to do so. This is why it is rarely considered clinically, even though it is a very common pathogen.

D W - [Myalgia and hypertension (typically 155/95.) Began (2003) taking doxycycline and macrolide and later adding metronidazole. No medication now. Morning BP typically 110/75]

I used to take natto kinase with my CAP, by discontinued as you can't take it within a month of consuming aspirin. I take aspirin to relieve migraines, which I've started getting on a regula basis

---------------------------------------------------------------------------------------------------------------Doing Thibault protocol (NAC/mino/roxi/tini/nattokinase)...but considering morphing to Stratton protocol

Hi everyone, I need a little help on this subject...I'm Cpn positive and in the process of organising my protocol and CAP for the infection, but my stool microbiology just came back positive for klebisiella pneumonia eat 4+ out of 1-4 scale. This is leaving me somewhat confused to how to go about my cpn protocol, combine and target both of these issues. I'm a little concerned about possibility of biofilm problem and do not know what to do now, help would be much appreciated thank you.