Bacterial Genomics Reveals MS Trigger
Infection with a common bacteria could be the switch that turns on the autoimmune response in multiple sclerosis (MSi) according to the findings of Wayne State University PhD graduate, Derek Lenz, now of the Scripps Research Institute in La Jolla, Calif. He described the work he carried out as part of Robert Swanborg’s team at Wayne State University School of Medicine. He said studies in rats show that an antigeni found in the bacteria Chlamydia pneumoniae mimics part of a myelini protein in the animal’s central nervous system. When injected into the animal, it provokes the immune response that causes the rodent version of MS, experimental allergic encephalitisi.
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The difference between what we do and what we are capable of doing would suffice to solve most of the world’s problems. Mohandas Gandhi
Michèle (UK) GFAi: Wheldon CAPi 1st May 2006. Daily Doxyi, Azi MWF, metroi pulse.
Fibro, CFSi, Myco, CPNi, Stratton protocol, Zithro 500mg M/W/F/S, Doxyi 100mg 2x day, NACi 1200mg 2x day, Flagyli and INHi 2 week pulses 400 mg 3x day, Rifampin, 300mg 2x day, Still cant shake it but improving.
Yet, we are the initiators and have been for a very long time.Thank goodness, we are not alone and have the brilliant questioning that makes this site so unique.
Educating neuros is a good idea if one can bear hearing the negativity aimed at all of us.
Everyone here, man or woman - YOU GO!!!!!!
Happy 2009. I am with all of you, in spirit, hopes and desires.
Loulou
diagnosed MSi Jan.2000 , chronic neurological lyme disease Nov.2002.
doxyi 100 mg. 1BID. roxyi.150 mg.? BIDi,adding rifampin soon, pulsed tinii. every 3 weeks, as of oct.17/08, rifampin,naltrexone (LDNi),NACi, nystatin, major wheldon supplemrnts daily,
Season's greetings everyone, but has anyone noticed that this link from Wayne State University is six years old?.............Sarah
An Itinerary in Light and Shadow
Wayne State has been doing work of this sort for many years.Dr. Lida Mattman , recently deceased, virologist, etc. penned the medical book Stealth Pathogens in the 80s out of Wayne State. Originally professor emeritus from Yale - a brilliant woman and ahead of her time.
So we all should pay attention.
Loulou
diagnosed MSi Jan.2000 , chronic neurological lyme disease Nov.2002.
doxyi 100 mg. 1BID. roxyi.150 mg.? BIDi,adding rifampin soon, pulsed tinii. every 3 weeks, as of oct.17/08, rifampin,naltrexone (LDNi),NACi, nystatin, major wheldon supplemrnts daily,
I didn't really think it mattered... but don't you find it interesting that 6 YEARS AGO they made the possible connection??
JeanneRoz ~ DXi'd w/ CPNi 4/2007; 6/07 -"officially" dx'd w/CFIDSi/FM; also: HHV6, EBVi, IBSi-C, 100 Doxyi:BIDi; 500 mg Biaxin BIDi; Tindamax Pulses, B12 shots, ERFA Dessicated Thyroid,Cortef, Iodoral 25 mg, Vit D-6,000 uni
PPMSi-misdiagnosed 2001-diagnosed 2006. Also maybe Lyme. Minocycline 7 mos.- resulting bronchitis 5 months.Go to private m.d. out-of-plan. Wheldon CAPi 3/2/07 - Now doing 100 doxyi; 125mg. azith; substituting acupuncture for pulsing.
Autoimmune or not?????????????That is the pervasive question..................Some neuros say yes autoimmune, others say no...
Dr. Wheldons protocol gives us some hope..The rest are merely names - I keep going.What else is there??
LOULOU
diagnosed MSi Jan.2000 , chronic neurological lyme disease Nov.2002.
doxyi 100 mg. 1BID. roxyi.150 mg.? BIDi,adding rifampin soon, pulsed tinii. every 3 weeks, as of oct.17/08, rifampin,naltrexone (LDNi),NACi, nystatin, major wheldon supplemrnts daily,
Sorry, everyone, but I didn't think anyone had noticed the date. This is old news and DW was corresponding with Hudson years ago. I thought it was sad that things had changed so little since then................Sarah
An Itinerary in Light and Shadow
It is definitely sad. Thank you DW .
Things in medicine are profoundly slow.Sarah, I'm sure you know more about the inner circles of the med. system than most?
This, so to speak, hierarchy makes us so aware that pharmaceutical companies appear to unfortunately govern medicine and the "practice" of it.eg. no cause, no cure, bacterial, viral, and the list goes on and on.....
Forget the politics as much as possible. Do what you can . Exercise, go outside (weather permitting), stay on CPNi.....................
Loulou
I'm starting to sound political. Must be the times we're living in.
Happy 2009
diagnosed MSi Jan.2000 , chronic neurological lyme disease Nov.2002.
doxyi 100 mg. 1BID. roxyi.150 mg.? BIDi,adding rifampin soon, pulsed tinii. every 3 weeks, as of oct.17/08, rifampin,naltrexone (LDNi),NACi, nystatin, major wheldon supplemrnts daily,
The difference between what we do and what we are capable of doing would suffice to solve most of the world’s problems. Mohandas Gandhi
It is possible it is autoimmune and directly attacks tissue, HSPi 60 maybe, and very likely genetic and environmental. That is maybe why it has taken so long to tie everything together, many variables.
The body is very complex, it is very hard to experiment with people much less track them. Medicine is very political. All things to slow finding the cure. Many very fine doctors now are on the germs trail, it will get a lot harder for it to do damage as before.
Cpni, Mycoplasma, Chronic EBVi, M.S.(MRI, Spinal Tap-greater than 5 oligoclonal bands and VEP), PANDAS(OCD). Wheldon CAPi (started 12/08), Azithromycin/Clarithromycin(12/09), Lithium, Lamictal, NACi(2.4g/day), D3(15,000IU/day)
Whoops! Confused for a change.....................not cpn YES capi, YES antis.
Thanks Mac for pointing that out- I missed it.
Loulou
diagnosed MSi Jan.2000 , chronic neurological lyme disease Nov.2002.
doxyi 100 mg. 1BID. roxyi.150 mg.? BIDi,adding rifampin soon, pulsed tinii. every 3 weeks, as of oct.17/08, rifampin,naltrexone (LDNi),NACi, nystatin, major wheldon supplemrnts daily,
If Dr. Lida Mattman wrote the medical book "Stealth Pathogens" in the 80's, and was a Nobel Prize candidate because of it, then why in the world are so many having so much trouble finding doctors who will go along with this protocol, and why is there such a battle within the medical community? I honestly and truly don't understand.
Kelly
Diagnosed FMSi Feb '07. 2x/day: 600 mg NACi, 100 mg Doxyi, 500 mg Amoxicillini, 2000 iu Vit. D. 450 mg Valcyte. 250 mg Azi M/W/F. 500 mg 375 mg Flagyli pulses every 3-4 weeks. Started CAPi June '07.
Progressive MSi dx2006. LDNi & CAPi: Wheldon version. All supps. Doxyi 200mg. Zithi 250mg. Metroi 400mg.Water kefir. Pulses- a lot!...I can because I think I can.
I wish I knew a solid unbiased answer to your valid questions.
Get involved with ILADS. mORE INFO THat ,as me, will make you more aware, however, add to your confusion. Hoping this baffling info will stop, once and for all BUT I bet it doesn't!!
Happy 2009
Loulou
ps Let it suffice to inform you that Dr. Mattman was hidden, literally, for her beliefs, almost thrown in jail, etc.etc. I stayed with her close to the end of her proud,informative life. I learned a lot from her.
diagnosed MSi Jan.2000 , chronic neurological lyme disease Nov.2002.
doxyi 100 mg. 1BID. roxyi.150 mg.? BIDi,adding rifampin soon, pulsed tinii. every 3 weeks, as of oct.17/08, rifampin,naltrexone (LDNi),NACi, nystatin, major wheldon supplemrnts daily,
Wow, LouLou - where was Erin Brockovich during all of this?! Dr. Mattman's story sounds fascinating - it would be great to see a book written about her life! She really was the pioneer, wasn't she? So sad that she was also a pioneer for those persecuted for daring to have evidence that contradicts those who hold the power.
Kelly
Diagnosed FMSi Feb '07. 2x/day: 600 mg NACi, 100 mg Doxyi, 500 mg Amoxicillini, 2000 iu Vit. D. 450 mg Valcyte. 250 mg Azi M/W/F. 500 mg 375 mg Flagyli pulses every 3-4 weeks. Started CAPi June '07.