Bacterial Genomics Reveals MS Trigger
Infection with a common bacteria could be the switch that turns on the autoimmune response in multiple sclerosis (MSi) according to the findings of Wayne State University PhD graduate, Derek Lenz, now of the Scripps Research Institute in La Jolla, Calif. He described the work he carried out as part of Robert Swanborg’s team at Wayne State University School of Medicine. He said studies in rats show that an antigeni found in the bacteria Chlamydia pneumoniae mimics part of a myelini protein in the animal’s central nervous system. When injected into the animal, it provokes the immune response that causes the rodent version of MS, experimental allergic encephalitisi.