Azoles Antimicrobials

Azoles Antimicrobials. Fasigyn   (Tinidazole),  some other brand names, Tindamax (Tinidazole)Other azoles include Flagyl (metonidazole) and others. Tinidazole,  How does it work?

Tinidazole belongs to a group of antimicrobials called the azoles. It works by entering the cell and binding to genetic material (DNA). This prevents the formation of further genetic material and therefore stops the bacteria from reproducing. Tinidazole is an antibiotic specifically used to stop the spread of infections which do not require oxygen to grow. These sorts of microorganisms commonly infect the gut, bones, brain and lungs.
 What is it used for?·  Amoebic infection of the liver ·  Bacteria of the gut that can cause ulcers ·  Infection that is caused by bacteria that grow without                      the need for oxygen (anaerobic bacteria) ·  Inflamation of the vagina resulting from genital trichomoniasis ·  Painful inflammation and ulcers of the gums (ulcerative gingivitis) ·  Parasitic gut infection caused by the protozoa Giardia lamblia ·  Prevention of infection (usually after surgery) ·  Sudden severe diarrhoea due to infection caused by the amoeba Entamoeba histolytica     (acute   amoebic dysentry) ·  Type of infection of the kidney, bladder and urethra (urogenital trichomoniasis) 


·  Do not drink alcohol whilst taking this medicine. ·  Clinical and laboratory monitoring is required if treatment is greater than 7 days. Use with caution in;·  Impairment of brain function caused by liver disease ·  Liver disease  Pregnancy and Breastfeeding
Certain medicines should not be used during pregnancy or breastfeeding. However, other medicines may be safely used in pregnancy or breastfeeding providing the benefits to the mother outweigh the risks to the unborn baby. Always inform your doctor if you are pregnant or planning a pregnancy, before using any medicine.
·  Pregnant women should consult their doctor before using this medication. The suitability of this medication depends on the stage of pregnancy. ·  This medicine passes into breast milk. It is recommended that mothers should avoid using this medicine while breastfeeding. Seek medical advice from your doctor.  

Label warnings

·  Avoid alcoholic drink whilst taking this medication. ·  Take at regular intervals. Complete the prescribed course unless otherwise directed. ·  Take this medication with or after food. ·  This medication is to be swallowed whole, not chewed. Side effects

Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with this medicine. Because a side effect is stated here, it does not mean that all people using this medicine will experience that or any side effect.
·  Abdominal pain ·  Fits (convulsions) ·  Disorder of the peripheral nerves causing weakness and numbness (peripheral neuropathy) ·  Nausea and vomiting ·  Bitter or metallic taste ·  Sensation of a furry tongue ·  Darkens the colour of the urine ·  Headache ·  Skin rashes ·  Allergic reaction to active ingredient ·  Dizziness The side effects listed above may not include all of the side effects reported by the drug's manufacturer. For more information about any other possible risks associated with this medicine, please read the information provided with the medicine or consult your doctor or pharmacist. How can this medicine affect other medicines?

Tinidazole should not be taken with alcohol as it may cause flushing, abdominal cramps, vomiting and an increased heart rate. This medication may reduce the effectiveness of the combined oral contraceptive pill.