27 Apr 2018
liz n

Azithromycin dosage


My doctor says that using 500mg of Azithromycin once a week will be as effective as using it at 250 mg three times a week (due to its long action in the body). Does anyone recommend this?I took 500mg two days ago and have had swollen glands, a sore throat, fatigue and slight nausea since. Would 250mg three times a week be easier in terms of side effects?ThanksLiz n


Well, I'm no expert, but I would have to agree with you.   Ella found the Azithromycin particularly difficult to get used to and a smaller dose meant that we could control the timing better.   If she still was not feeling well enough to take the next one, we could delay it for a day or two.   It took about 6 to 8 weeks for her to tolerated the 750mg a week the Wheldon protocol recommends.

Unless they are very familiar with the difficulties of treating Cpn doctors may not always realised the effect that Azi can have on CPn in terms of die-off reactions.

Michele (UK) GFA: Wheldon CAP1st May 2006 . 26th March 2007 continuous Flagyl at 400mg with 5 day pulses at 1200mg every three weeks. Spokesperson for Ella, RRMS Wheldon CAP 16th March 2006

Michèle (UK) GFA: Wheldon CAP 1st May 2006. Daily Doxy, Azi MWF, metro pulse.

 Your doc may be right as to the pharmacokinetics, but it is harder to control the initial reactions to the first blood concentrations of a dose. Your reactions are proof of that. It may be that initially one 250mg dose a week is what you can tolerate to start with, then waiting until reactions subside before adding a second dose, etc. The smaller dosing allows you to work up more gradually and pay attention to your own cycle of reactions.

CAP for Chlamydia pneumonia since 11/04. 25yrs CFS & FMS- Currently: 150mg INH, 200 Doxycycline, 500mg MWF Azithromycin, 500mg Tini daily (Continuous protocol)

Not a doctor; I don't even play one on tv.  It just seems to me the whole purpose of Wheldon's 750/week is to strike a certain level that is always present in your body. Taking 500 at once seems counterproductive to that idea. Why not print out Wheldon's protocol and present it to your doctor? He explains his rationale for the choices of meds and adjuncts very clearly therein.

The difference between what we do and what we are capable of doing would suffice to solve most of the world’s problems.  Mohandas Gandhi

The difference between what we do and what we are capable of doing would suffice to solve most of the world’s problems. Mohandas Gandhi