I took Lyrica and gained 20 pounds so I stopped it. Lately I have had a lot of pain so thinking about Savella. My doc gave me some samples. Some of the side effects include nausea (which most of us have anyway), insomnia (which I have real bad), constipation (again, IBS-c), etc. I also take Wellbutrin and Lamictal. Should I try it? I also read the mfg website that says FMS is caused by spinal cord injury I think it said. I had back surgery and got FMS a few months after but not everyone has back (spine) problems so I don't understand how they can say that. Apparently they don't get it either. I guess Savella and Lyrica, just blunt the pain but they don't get to the cause of course.