Antibiotics and antimicrobials; tablets vs capsules when available and generic vs brand names
My question primarily is from a user perspective, regarding the cost/vs side effects of purchasing brand name capsules vs tablet forms when there is a choice.
Cost seems to often be in favor of the tablet form.
For those with no stomach distress with the capsules, seems either might be fine.
For those with stomach respsonse to the capsules (such as myself) I have now realized that I do have a choice of the tablet form,
as well as a higher priced choice of another brand name Doryx that is reported to have less stomach response symptoms. Reported to be newer and more costly than either the tablet generic or the capsule generic.
Early on my response to Doxy without food and even with food if not a full protein/fat containing meal was extreme pain and nausea ( the type that you might wish to vomit but never did fortunately). Through a process of trial and error, the solution for me was the well timed ingestion of the capsule halfway into the meal. One the meal had moved into the small intestines the symptoms very quickly faded away.
Over the course of the past 15 weeks, I have had a few slips in this approach, taking the Doxy at the beginning of the meal or forgetting and taking it at the end of the meal. Seems that perhaps my stomach lining or muscles may be clearing some of the C.Pn.
I have read that abdomenal pain can be one of the many subjective presentations of porphoria. Given my high starting dose of Doxy and my High IgG (past infection) 1:512, and IgM ( active infection) also 1:152 a high titers as well as ever increasing brain fog prior to any treatment, my supposition is that I may have been having die-off earlier than some as a result of some active infection somewhere in my system other than my lungs. Regardless of the reason it was a writhing pain and nausea.
It amazes me that I find myself seemingly in such a minority situation amongst folks here on this site. From what I read, most folks seem to be guzzlng down the Doxy with a big glass of water and being so OK with that at least from the immediate stomach response perspective.
Also of note is my extreme sun sensitivity to the Doxy. I was careful, used lots of sun block the few times I went out in the sun, wide brimmed hat etc.
However one day I took a 2 hour drive on the interstate. Never thought that I could get a burn through the auto tined glass. Painful to touch on my hands that were on the steering wheel the entire time. Took several weeks to heal. Bridge of my nose was red and sore too.. The most interesting manifestation was the very bright red spots that appeared on my arm, particularly the left towards the drivers side window and the direction of the mid-afternoon sun for the entire trip.
Two doctors and a pharmacist saw it. Family Practitioner (GP) said it was a Doxy reaction and that no way would I be able to keep taking it. FFC doctor said sure we could substitute and wrote an RX for Cipro. I decided that since Cipro info had the same cautions might as well stay with the doxy. I reported my action of staying on the doxy and doubled my efforts to shield my skin from the sun.
After several weeks the bright red, ever so slightly palpable spots darkened and eventually flaked off.
My hypothesis it that it was porhporia related. I am glad for the cool autumn weather and the several wide brim hat and cotton workgloves that I wear as necessary for driving extended periods in the bright sunlight.
So I am looking for feedback from those that can make a comparison regarding the tablet form of Doxy vs Capsule and the brand vs generic varieties from the perspective of having similar responses to it as mine and what worked for you. As well as those who have photosensitive experiences could be helpful.