MediTest
27 Apr 2018
Author
Red
Title

A couple funny stories about Vitamin D3

Body

On the lighter side:

You know, since my brother was dx'd with his brain tumor last June, I've become a fanatic about Vitamin D3 and the studies that suggest it likely has some major health benefits (including several cancer fighting effects). So, I've started launching into a whole series of unsolicited lectures on the anti-cancer and anti-microbial effects of Vitamin D3 with just about anyone at a cocktail party I can bore to tears with this information.

Comments

Oh Red, I too have been a shameless proselytizer for vitamin D.I think my friends are sick of hearing about it and several have gone out and bought some just to keep me from yammering at them. My husband is now taking it and getting some sun exposure too. He had a brief brush with a virus this Fall but got over it in a day. He says he has never felt so healthy.

BTW, You can subscribe to the Vit. D newsletter from the Vit. D Council. Here's one of the latest newsletters:
http://www.vitamindcouncil.com/

The links didn't paste but you can get a good idea of what Dr. Cannell is saying. He is so right!

Raven

The Vitamin D Newsletter

December, 2007

Does vitamin D prevent cancer? If it does, will doctors who ignore the research end up with blood on their hands? The press makes it easy for doctors to believe what they want to believe. Below are six stories about the same scientific study; read the six different headlines. According to your a priori beliefs, you can choose the story you want to believe and read that one. Don't feel bad, we all do it. As Walter Lippman once said, "We do not see and then believe, we believe and then we see."

Vitamin D cuts colon cancer death risk

Study Finds No Connection Between Vitamin D And Overall Cancer Deaths

Vitamin D protects against colorectal cancer

Vitamin D May Not Cut Cancer Deaths

Vitamin D protects against colorectal cancer

Scientists advise a vitamin D downgrade as there is no real proof ...

Another option is to read the study yourself.

Freedman DM, et al. Prospective Study of Serum Vitamin D and Cancer Mortality in the United States. J Natl Cancer Inst. 2007 Oct 30; [Epub ahead of print]

What Dr. Freedman actually discovered is that when you take a very large group of people (16,818), some as young as seventeen, measure their vitamin D levels, and then wait about ten years to see who dies from cancer, you find 536 die and that a vitamin D level from ten years earlier is not a good predictor of who will die from cancer. However, even a level drawn ten years earlier predicted that those with the lowest level were four times more likely to die from colon cancer, suggesting, as Ed Giovannucci has, that colon cancer may be exquisitely sensitive to vitamin D. Furthermore, 28 women got breast cancer, 20 in the group with the lowest vitamin D level but only 8 in the highest. The breast cancer findings were not statistically significant - even during a very long breast cancer awareness month - but can you imagine what critics at the American Cancer Society would be telling women if the numbers were reversed, if the 20 women who got breast cancer were in the high vitamin D group?

Another large epidemiological study appeared about breast cancer the very next day. This time, the press passed on the story and the American Cancer Society was mum, no editorials by Dr. Lichtenfeld, their spokesman, in spite of breast cancer awareness month.

Abbas S, et al. Serum 25-hydroxyvitamin D and risk of postmenopausal breast cancer - results of a large case-control study. Carcinogenesis. 2007 Oct 31; [Epub ahead of print]

In the above study, 1,394 women with breast cancer were case-controlled with a similar number of women without breast cancer. The women with breast cancer were three times more likely to have low vitamin D levels. That is a lot of women who may be dying during next year's breast cancer awareness month.

Both of the above studies were epidemiological, not randomized controlled trials. Of course a randomized controlled trial has already shown a 60% reduction in internal cancers in women taking even a modest 1,100 IU per day of vitamin D.

Lappe JM, et al. Vitamin D and calcium supplementation reduces cancer risk: results of a randomized trial. Am J Clin Nutr. 2007 Jun;85(6):1586-91.

What is interesting is the difference in the response of the Canadian Cancer Society and the American Cancer Society. The Canadian Cancer Society has advised all Canadians to take 1,000 IU per day - not enough but a good first step - and for immediate additional large scale clinical trials. The Canadians simply performed a risk/benefit analysis. What is the risk of treating vitamin D deficiency versus what are the potential benefits? They quote the American Food and Nutrition Board, which says 2,000 IU/day is safe for anyone over the age on one to take, on their own, without being under the care of a physician. If there is little or no risk, then the next question is what are the potential benefits of treating vitamin D deficiency? This is not quantum mechanics.

Cancer society calls for major vitamin D trial

The Canadians acted because the Canadian government knows it could save billions of dollars by treating vitamin D deficiency.

Vitamin D Deficiency Drains $9 billion From Canadian Health Care ...

If wide spread treatment of vitamin D deficiency became the rule, ask yourself, "Who would be helped and who would be hurt." First ask yourself that question about Canada and then about the USA. Remember, in Canada, the government directly pays for its citizen's health insurance; in the USA, private insurance is the norm. In Canada, the government is realizing they could save billions if vitamin D deficiencies were treated. In the USA, a large segment of the medical industry would be hurt, some anti-cancer drug manufacturers would have to close their doors, thousands of patents would become worthless, lucrative consulting contracts between industry and cancer researchers would dry up.

Both Canadians and Americans are shocked to think their doctors care about money, are in the illness business. In some ways people think of their doctors like they do their local public schools. They know medicine is a business and know doctors do things for money but they don't think their own doctors do. Likewise they think public schools are in bad shape but think their local schools are above average. They think their doctor is above average, like their "Lake Woebegone" kids.

Lake Woebegone Effect

The fact is that doctors, hospitals, regional cancer centers, and the cancer drug manufacturers are all in business to make money and all of these businesses make money off the sick, not off the well. Just a fact, but, as Aldous Huxley once observed, "Facts do not cease to exist because they are ignored."

Vitamin D will save the Canadian government enormous amounts of money but will cause widespread economic disruption in the USA. Do the physicians leading the American Cancer Society have strong economic ties to the cancer industry in the form of patents, stock options, and consulting fees? If so, what do you expect them to do? What would you do? It's simple. You would believe what you have to believe, what you need to believe, that is, anything with the word "vitamin" in it is simply the latest Laetrile. Look to Canada, not the USA, to lead the way.

Vitamin D may fight cancer

What about American physicians? They are apparently waiting for the American trial lawyers to smell a tort. After all, the case is quite simple. Doctor, did you advise Mrs. Jones to avoid the sun? Doctor, did you tell her the sun is the source of 90% of circulating stores of vitamin D? Doctor, did you prescribe vitamin D to make up for what the sun would not be making? Doctor, did you measure her vitamin D levels? So you had no way of knowing if your sun-avoidance advice resulted in vitamin D deficiency? Doctor, do you know our expert tested her vitamin D level and it was less than 20? Doctor, did you tell her about any of the studies indicating vitamin D deficiency causes cancer? Doctor, did you know Mrs. Jones has terminal breast cancer and will be leaving behind a loving husband and two young children?

And what about the American Cancer Society? Dr. Lichtenfeld, their spokesman, quickly gave his opinion; from what I can tell the first time he ever commented on a vitamin D study. That is, he has ignored the hundreds of positive epidemiological studies, ignored the incredible randomized controlled trial, but he jumped on this one:

Maybe Vitamin D Isn't The Answer After All

Dr. Lichtenfeld, implied the Canadian Cancer Society has acted precipitously in recommending that all Canadians take 1,000 IU of vitamin D daily. He implied that Americans should placidly wait until more randomized controlled trials, such as Lappe JM, et al (above), accumulate before they address their vitamin D deficiency. That is, nothing should be done until more randomized controlled trials prove vitamin D prevents cancer, one randomized controlled trial is not enough; epidemiological studies are not enough, animal studies are not enough, multiple anti-cancer mechanisms of action are not enough? If that is his position, I challenge him to point to one human randomized controlled trial that proves smoking is dangerous?

If he cannot, then he must admit that the American Cancer Society's position on smoking is entirely derived from epidemiological studies, animal studies, and a demonstrable mechanism of action, not on human randomized controlled trials? Vitamin D not only has hundreds of epidemiological studies, thousand of animal studies, and at least four anti-cancer mechanisms of action, vitamin D deficiency has something smoking does not have, it has a high quality randomized controlled trial. If future randomized controlled trials fail to show vitamin D prevents cancer - and Dr. Lichtenfeld better hope they do - he can have the satisfaction of saying "I told you so." If future randomized controlled trials confirm vitamin D prevents cancer, then he needs to look at his hands, the red he sees is the blood of needless cancer deaths.

John Cannell, MD

The Vitamin D Council

9100 San Gregorio Road

Atascadero, CA 93422

This is a periodic newsletter from the Vitamin D Council, a non-profit trying to end the epidemic of vitamin D deficiency. If you don't want to get the newsletter, please hit reply and let us know.

This newsletter is not copyrighted. Please reproduce it and post it on Internet sites.

Remember, we are a non-profit and rely on donations to publish our newsletter and maintain our website. Send your tax-deductible contributions to:

The Vitamin D Council
9100 San Gregorio Road
Atascadero, CA 93422

Feeling 98% well-going for 100. Very low test for Cpn. CAP since 8-05 for Cpn/Mycoplasma P.,Lyme, Bartonella, Mold exposure,NAC,BHRT, MethyB12 FIR Sauna. 1-18-11 begin new treatment plan with naturopath

Red

Hi Raven,

Too funny that you are "a shameless proselytizer for vitamin D" too. I love the Vit D Council site, and I am encouraged that Google News returns a new article on Vit D almost every day now.

FYI, there was an interesting study on Vit D3 and the Intestinal Mucosal Barrier recently. I don' think I saw it here on the site, and I thought those with IBS issues might like to read it:

Novel Role of the Vitamin D Receptor in Maintaining the Integrity of the Intestinal Mucosal Barrier.

 

Keep on shamelessly spreading the news... 

On Combined Antibiotic Protocol for Cpn in Rosacea 01/06 - 07/07, On Vit D3 + NAC since 07/07 and daily FIR Sauna since 08/07

Treatment for Rosacea

  • CAP:  01/06-07/07
  • High-Dose Vit D3, NAC:  07/07-11/08
  • Intermtnt CAP, HDose Vit D3:  11/08-01/09
  • HDose Vit D3, Mg, Zn: 01/09-

For some reason, and maybe  someone can enlighten me, when I add Vit D to my regimen, I get severely depressed. It usually about the 3rd when the depression hits me.  I've tried to add Vit D on 3 different occasions and get the same response.  Then it takes about another 2 days after stopping the Vit D for my depression to lift.  Lord knows, I sure could use the Vit D for weight loss. I have about 20 that I need to loose.  

Mphs, TN. CFS, hypoT, weak adrenals, 37 w/hormones of 80 yo. right arm neuropathy. 6/26/07- CPN Titer 1:256 (normal 1:16); 6/27/07- NAC; 7/2/07- doxy 100, 2xday; 7/19/07-9/7/07- Biaxin. 9/8/07-azith 250 mg m/w/f. 10/18/07-1st flagyl pulse

Mphs, TN. CFS, hypoT (Hashi), adrenal fatigue, hormonal inbalance. right arm neuropathy-getting better. cpn, myco, EBV, CMV, HHV-6. Cap began in 6/07. NAC 2400mg, mino 100mg bid, biaxin 500mg bid. cytomel, flagyl bid continuously.

Red

Hi Sharon,

When I talked with him, Dr S suggested that the addition of Vit D3 would likely cause me a great deal of increased die-off due to its ability to interfere with Cpn's ability to parasitize cells via Cpn's mechanism of preventing apoptosis or normal cell death (through the NF-KappaB pathway). He said Vit D3 would likely help kill off the intracellular forms of Cpn (the RB and Cryptic forms) and thus cause increased die-off effects and spilled porphyrins (and their effects). He was certainly right in my case as I too felt increased die-off and porphyrin effects, including the increased depression you mention.

Remember the rule to go only as fast as you can.     Give yourself time to get better with the antibiotics, and once you do start feeling much better (and are able to tolerate flagyl pulses well - YOU'LL GET THERE, TRUST ME), don't be afraid to try adding Vit D3 back in again very slowly...

Hang in there...

On Combined Antibiotic Protocol for Cpn in Rosacea 01/06 - 07/07, On Vit D3 + NAC since 07/07 and daily FIR Sauna since 08/07

Treatment for Rosacea

  • CAP:  01/06-07/07
  • High-Dose Vit D3, NAC:  07/07-11/08
  • Intermtnt CAP, HDose Vit D3:  11/08-01/09
  • HDose Vit D3, Mg, Zn: 01/09-

I have mentioned before that my breast thermography results last year were 40 & 50% up the risk scale last year.  The news the doc said we need to watch out.  The girls were on full watch alert.

This year my thermography results for both my girls had me down at the 0% end of the risk scale.  I hypothesize it is due to the 5000 iu of Vitamin D & the Curcumin.  I wish people would listen to me about these things, but I am all too familiar with the "being blown off" syndrome.  Oh well!

You can only lead a horse to water, up to them if they drink

CFIDS/ME 25yrs, FMS, IBS, EBV, Cpn, (insomnia - melatonin, GABA, tarazadone, temazepam, novocyclopine, allergy formula, 2 gm tryptophan), Natural HRT peri-M, NAC 2.5 gm, 6-07 Doxy 200 mg day pm, Azith 375 mg M/W/Fday, 10-30-07 3rd pulse 2 X 250 mg 2day

CFIDS/ME, FMS, MCS, IBS, EBV, CMV, Cpn, H1, chronic insomnia, Chronic Lyme, HME, Babesia, Natural HRT-menopause, NAC 2.4 gm,Full CAP 6-2-07, all supplements+Iodorol, Inositol-depression, ultra Chitosan, L lysine Pulse#27 04-19-10 1gm Flagyl/day-5 days<

Thank you Red for the explanation.  makes sense the way you explained it.   

Mphs, TN. CFS, hypoT, weak adrenals, 37 w/hormones of 80 yo. right arm neuropathy. 6/26/07- CPN Titer 1:256 (normal 1:16); 6/27/07- NAC; 7/2/07- doxy 100, 2xday; 7/19/07-9/7/07- Biaxin. 9/8/07-azith 250 mg m/w/f. 10/18/07-1st flagyl pulse

Mphs, TN. CFS, hypoT (Hashi), adrenal fatigue, hormonal inbalance. right arm neuropathy-getting better. cpn, myco, EBV, CMV, HHV-6. Cap began in 6/07. NAC 2400mg, mino 100mg bid, biaxin 500mg bid. cytomel, flagyl bid continuously.

Red

Glad it makes sense, Sharon. And glad to hear you're now at the 0% end of the risk scale, Ruthless1. That's really great news!

On Combined Antibiotic Protocol for Cpn in Rosacea 01/06 - 07/07, On Vit D3 + NAC since 07/07 and daily FIR Sauna since 08/07

Treatment for Rosacea

  • CAP:  01/06-07/07
  • High-Dose Vit D3, NAC:  07/07-11/08
  • Intermtnt CAP, HDose Vit D3:  11/08-01/09
  • HDose Vit D3, Mg, Zn: 01/09-

Another two proselytizers on this side of the pond, but guess who the worst cynics tend to be?  Hospital doctors and GPs and therefore those people who won't do anything unless they have their doctor's full approval...........Sarah    An Itinerary in Light and Shadow   Completed Stratton/Wheldon regime for aggressive secondary progressive MS in June 2007, after four years, three of which intermittent.   Still slowly improving and no exacerbation since starting. EDSS was 7, now 2, less on a good day.

Completed Stratton/Wheldon regime for aggressive secondary progressive MS in June 2007, after four years, three of which intermittent.   Still improving bit by bit and no relapses since finishing treatment.

So this guy walks into a bar in So Cal and asks for 5000 units of Vitamin D. The bartender asks, "You want that with or without the catelecidin inducing properties?" LOLImage removed.

Yes, we are really koo-koo, but who else gets it? I love the idea of a Vit D craze hitting So Cal, and being able to say, "Yup, that was my buddy Red!" Hey, they elected the Terminator, so anything can happen.

I think that's really cool, particularly the weight loss. If anything will get them, that will. By the way, the kind of inflammatory action your mo is suffering from is not yet amenable to Vitamin D, although a Prozac atomizer might be useful. "Oh no, Mom, it's just an air freshener."

Yours in humor,

Jim 

CAP for Chlamydia pneumonia since 11/04. 25yrs CFS & FMS- Currently: 200 Doxycycline, 500mg MWF Azithromycin, Tini pulses.

A motto, not an aspiration: "Anything worth doing is worth overdoing."

Red

Warning, never read a post that starts with the line "So this guy walks into a bar" while drinking hot coffee! Too funny, Jim! But I'm hoping Vit D3 might now help with 3rd degree burns...Image removed.

And Sarah, glad to hear you all are shamelessly working the other side of the pond. You know, I started out very conservatively, telling everyone to run 2000iu by their doctors before trying it (this was before the Canadian pediatric society started urging pregnant and nursing mothers to ask their docs about taking 2000iu). Now I figure if the CPS thinks its safe for pregnant Canadiennes, then it's probably safe for the average bear or bearess...

My dad asked his dermatologist (I know, I know, he might as well have asked his banker, but it was his first doctor visitImage removed.), and his derm said that he thought taking 2000iu was a great idea and evidently he and his wife had been quietly doing 2000iu themselves for some time, likely behind closed doors so as not to get become labelled a "Kook" with the rest of us. My dad then asked about eventually going to 4000iu, but the doc said he wasn't so sure about this. Now, with the stiff neck a thing of the past, my dad seems to be more sure of it himself. Anyway, I'd give the derm one very big antimicrobial thumb up for being fairly well informed.

My sister on the other hand just a couple of weeks ago asked her son's surgeon (my nephew had a benign parotid salivary gland tumor last year) about my nephew starting on 2000iu. She said it was followed by a lot of eye avoidance, mumbling and head-shaking which she couldn't really decipher. She then asked her kids' pediatrician, who my sister said was nice enough to say she'd never read anything on it (Hello! Does the woman read anything other than People Magazine?). She asked my sister to fax in the articles that I had sent and said she'd give them a good look over (I'm betting in between reading all about Brad Pitt and Angelina Jolie). Image removed.

If the doc's fax machine doesn't become jammed with the stacks of articles we're sending (including the Canadian pediatric society's recent recommendations), I'm hoping for a slow celebrity week where the doc actually reads some of them and ok's the use of 2000iu for the kids...

On Combined Antibiotic Protocol for Cpn in Rosacea 01/06 - 07/07, On Vit D3 + NAC since 07/07 and daily FIR Sauna since 08/07

Treatment for Rosacea

  • CAP:  01/06-07/07
  • High-Dose Vit D3, NAC:  07/07-11/08
  • Intermtnt CAP, HDose Vit D3:  11/08-01/09
  • HDose Vit D3, Mg, Zn: 01/09-

Hi Red, David's big thing is that probably most elderly people here are deficient in vit D.  Especially older people in rest homes or nursing homes.  Some of these never see a beam of sunlight from one month to the next.  They are more prone to various infections because of this and it becomes a vicious circle.   The hospital has very high rates of clostridium difficile in the older patients, probably for this reason, so he suggests to various clinicians that it would be a good idea to supplement their diet with vit D.  Shock, horror, what a strange idea!     Then I suggest to my mother, recently shown to have mild osteoporosis, that she would benefit from buying some vit D.  However, she prefers to take the giant thing she has to take once a week on an absolutely empty stomach, whilst standing up for half an hour.  I suppose the discomfort makes her feel that she is being more proactive, plus her GP said this was the thing to take and all her neighbours are on it.  Perhaps in summer, they could all go out onto the communal lawn and take it together, whilst enjoying the sunshine.     I do have quite  few friends of my own age who are converts, though..........Sarah    An Itinerary in Light and Shadow   Completed Stratton/Wheldon regime for aggressive secondary progressive MS in June 2007, after four years, three of which intermittent.   Still slowly improving and no exacerbation since starting. EDSS was 7, now 2, less on a good day.

Completed Stratton/Wheldon regime for aggressive secondary progressive MS in June 2007, after four years, three of which intermittent.   Still improving bit by bit and no relapses since finishing treatment.

Red